Innovations in Fermentation and Phytopharmaceutical Technologies

1st Edition - June 14, 2022
Editors: Hrudayanath Thatoi, Sonali Mohapatra, Swagat Kumar Das
Language: English
Paperback ISBN:
9 7 8 - 0 - 1 2 - 8 2 1 8 7 7 - 8
eBook ISBN:
9 7 8 - 0 - 1 2 - 8 2 1 8 9 2 - 1

Innovations in Fermentation and Phytopharmaceutical Technologies discusses recent advancements in the field of different bioprocessing aspects for the development of differ… Read more

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Innovations in Fermentation and Phytopharmaceutical Technologies discusses recent advancements in the field of different bioprocessing aspects for the development of different reactors, fermented products and phytopharmaceuticals. Written by leading experts in the field, the book presents the basic principles of upstream processing techniques, advanced downstream process technologies, and recycling of by-products during formation/production of various fermented and phytopharmaceutical products. The informative chapters in the book outline an application-oriented path for academicians, researchers and scientists in the field of industrial fermentation technology and phytopharmaceutical production.

Cover image
Title page
Table of Contents
Copyright
Contributors
Part A: Concepts of reactor designing
Chapter 1: Photo bioreactors for production of biodiesel from algae: A short review
Abstract
1.1: Introduction
1.2: Methods of biodiesel production from algae using PBR
1.3: Conclusion
References
Chapter 2: Mixing and agitation in photobioreactors
Abstract
2.1: Introduction
2.2: Mixing and agitation—Basic concepts
2.3: Mechanical agitation and mixing
2.4: Pneumatic agitation and mixing
2.5: Shear sensitivity of microalgal cells
2.6: Conclusion
References
Chapter 3: Membrane reactors for mammalian cell culture
Abstract
3.1: Introduction
3.2: Membrane bioreactor taxonomy
3.3: Differential aspects of membrane bioreactors over other reactors used in cell culture
3.4: Membrane bioreactors offer varying operations and modalities
3.5: Membrane bioreactors: Presenting numerous opportunities in mammalian cell product manufacturing
3.6: Conclusion
References
Chapter 4: Advances in fermentative systems for the production of ethanol from lignocellulosic biomass
Abstract
4.1: Lignocellulosic ethanol production process
4.2: Fermentation systems
4.3: Factors that affect alcoholic fermentation
4.4: Innovative strategies to improve ethanol productivity
4.5: Modeling, instrumentation, and process control strategies
4.6: Ethanol production at commercial scale
4.7: Conclusions
References
Chapter 5: Liquid extraction with immobilized liquids for product recovery from fermentation broths
Abstract
5.1: Introduction
5.2: Considerations for liquid extraction techniques to recover products from fermentation broths
5.3: Liquid membranes in microchannels
5.4: Membrane-assisted extraction
5.5: Conclusions and outlook
References
Part B: Upstream processes in bioprocessing of food, phytopharmaceuticals, and biofuels
Chapter 6: Recent advancements in the extraction of phytoconstituents from herbal sources
Abstract
6.1: Introduction
6.2: Recent advances in extraction techniques
6.3: Conclusion
References
Chapter 7: Emerging biosensor technology and its potential application in food
Abstract
7.1: Introduction
7.2: Potential application in food industry
7.3: Major industrial challenges and suggestions for food analysis
7.4: Future outlooks: Research development and further directions
7.5: Concluding remarks
References
Chapter 8: Current trends in green processing: Improvements of food product
Abstract
8.1: Introduction
8.2: Concepts and strategies of green physical processing
8.3: Green physical techniques and their applications in food improvement
8.4: Conclusion
References
Chapter 9: Phytochemicals and their nanoformulation in sustained drug delivery and therapy
Abstract
9.1: Lifestyle, metabolism, and disease link
9.2: Conventional therapeutic intervention and limitations
9.3: Phytochemicals as drug adjuvants and natural sources for therapeutic intervention
9.4: Types of phytochemicals and their use
9.5: Bioavailability of phytochemicals
9.6: Targeted therapy: The importance and requisites
9.7: Carriers for drug targeting
9.8: Diseases and nanodrug delivery of phytochemicals
9.9: SWOT analysis of phytochemical conjugated NPs
9.10: Conclusion
References
Chapter 10: Biohydrogen evolution in microbial electrolysis cell, a novel electrofermentation technology: Influence of reactor design
Abstract
10.1: Introduction
10.2: Microbial electrolysis cell
10.3: Challenges of EF at the industrial level
10.4: Future outlook
10.5: Conclusion
References
Part C: Downstream processes in bioprocessing of food, phytopharmaceuticals, and biofuels
Chapter 11: Mechanism, regulation, and inhibition of alkaloids in cancer therapy targeting JAK/STAT pathway
Abstract
11.1: Introduction
11.2: Structure of JAKs and STATs
11.3: Mechanisms of action of JAK/STAT signaling pathway
11.4: Role in development of cell division
11.5: Coordination between JAK and STAT
11.6: Regulations
11.7: Alkaloids targeting JAK/STAT pathway inhibition
11.8: Concluding remarks
References
Chapter 12: Biological production of xylitol: A process development approach
Abstract
12.1: Introduction
12.2: Xylitol and its potential application
12.3: Chemical route of xylitol production
12.4: Biological formation of xylitol
12.5: Microorganism used for xylitol production
12.6: Strain engineering strategy for xylitol production
12.7: Factors affecting xylitol production
12.8: Bioreactor operation and cell recycling
12.9: Downstream processing of xylitol
12.10: Conclusion
Competing interests
References
Chapter 13: Production of methyl ethyl ketone applying process intensification strategies
Abstract
13.1: Introduction
13.2: Cases of study
13.3: Methodology to design the intensified alternatives
13.4: Performance evaluation indices
13.5: Results
13.6: Conclusions
References
Chapter 14: Microbial xylanases, their structural characteristics, and industrial applications: A biotechnological advancement
Abstract
14.1: Introduction
14.2: Lignocellulolytic enzymes
14.3: Lignocellulolytic microorganisms
14.4: Xylanase
14.5: Application of xylanase
14.6: Isolation and screening of xylanolytic bacteria
14.7: Growth profile analysis
14.8: Biochemical identification
14.9: Enzyme assay for determination of xylanase activity
14.10: Optimization strategy for production of bacterial xylanase enzyme
14.11: In silico study
14.12: Conclusion
References
Chapter 15: Advances in fermented foods and therapeutics
Abstract
15.1: Introduction
15.2: Human evolution and nutrition
15.3: Fermented foods on society perspective
15.4: Health benefits of fermented foods and beverages
15.5: Potential benefits and risks of fermentation
15.6: The role of gut microbiota
15.7: Gut microbiota, fermented foods, and beverages
15.8: Conclusions
References
Part D: By-product utilization for production of value-added products
Chapter 16: Wine waste as a potential source of bioactive compounds
Abstract
Acknowledgments
16.1: Introduction
16.2: Grape composition
16.3: Grape waste
16.4: Common uses of grape waste
16.5: Bioactive compounds in wine waste
16.6: Solid and submerged fermentation
16.7: Concluding remarks
References
Chapter 17: Agro-industrial wastes for production of single-cell protein (SCP)
Abstract
Acknowledgments
17.1: Introduction
17.2: Single-cell protein
17.3: SCP production from agro-industrial wastes
17.4: Factors affecting the SCP process
17.5: Advantages and disadvantages of SCP
17.6: Concluding remarks
References
Chapter 18: β-Glucan production through bioconversion of sugarcane bagasse by Saccharomyces cerevisiae and Aspergillus niger
Abstract
18.1: Introduction
18.2: Materials and methods
18.3: Results and discussion
18.4: Conclusion
References
Chapter 19: Value-added product development from food scraps
Abstract
19.1: Introduction
19.2: Food waste as a renewable sourced material
19.3: Application of waste materials in the development of value-added product lines
19.4: Some of the other value-added products from food waste
19.5: Conclusions
References
Further reading
Chapter 20: Evaluation of various possibilities of underutilized fish processing biomass as a value-added product: A waste-to-wealth approach
Abstract
20.1: Introduction
20.2: Fish processing biomass
20.3: Bioactive compounds present in fish biomass and their utilization
20.4: Bioactive compounds from fish
20.5: Conclusion
References
Further reading
Chapter 21: Value-added products from industrial wastes of phytopharmaceutical industries
Abstract
21.1: Introduction
21.2: Drug and medicine in modern phytopharmaceutical approaches
21.3: Phytopharmaceutical wastes
21.4: Value-added products from phytopharmaceuticals
21.5: Biomass
21.6: Bioethanol
21.7: Enzyme production
21.8: Composting
21.9: Organic fertilizer
21.10: Fish and poultry feed
21.11: Microbial conversion
21.12: Conclusion
References
Index

Hrudayanath Thatoi

Hrudayanath Thatoi is a Professor and Head of the Department of Biotechnology, Maharaja Sriram Chandra Bhanja Deo University, Odisha, India. He is also Director of the Centre for Similipal Studies and Director, HRDC, Maharaja Sriram Chandra BhanjaDeo University. Prof. Thatoi obtained his M.Sc., M.Phil., and Ph.D. from Utkal University, Odisha, and has more than 17 years of teaching and 27 years of research experience. He is a fellow recipient of the Society of Applied Biotechnology (FSAB), India. He has contributed immensely to the field of microbiology and biotechnology throughout his research and teaching career. His research activities are based on exploration microbial diversity, bioremediation, biofuel production, mangrove biology, bioactivity studies in medicinal plants and mushrooms, ethnopharmacology and in silico drug design and modeling etc. Prof. Thatoi has handled many research projects funded by the State and Central Government including DST, Govt. of Odisha, UGC-DAE, Govt. of India, Department of Forest, Govt. of Odisha amongst others. So far, 17 students have obtained their Ph.D. under his guidance and supervision, and some 7 students are still continuing. As well as this, several M.Sc., M.Tech., and B.Tech.students have received his guidance for their dissertation works. Prof. Thatoi has published more than 250 research papers in various nationally and internationally reputed journals with total citations of above 5802 with an h-index of 40 and i10-index of 81, and more than 30 book chapters in National and International publications. Dr. Thatoi has also filed two patents (one India another abroad) to his credit. Prof. Thatoi has also authored 18 reference books and Seminar Proceedings through various notable publishers like, Elsevier, Springer, Taylor & Francis (CRC &Apple Publications), Studium Press LLC USA, IK International, Narosa publishers, Biotech Books, APH Publication, etc. He has also authored two text books on “Microbiology and Immunology”, published by India Tech Publication, New Delhi, and “Practical Biotechnology: Principles and Protocols” by IK International Publications, New Delhi for Graduation and Post-Graduation students in the field of Life Sciences and Biotechnology.

Affiliations and expertise

Professor, Department of Biotechnology, Maharaja Sriram Chandra BhanjaDeo University, Baripada, Odisha, India

Sonali Mohapatra

Sonali Mohapatra is an Assistant Professor in the Department of Biotechnology at Odisha University of Technology and Research (formerly College of Engineering and Technology) Bhubaneswar, Odisha, India. She has completed her B.Tech and M.Tech in the field of Industrial Biotechnology with distinction from Dr. MGR University, Chennai, India and Ph.D from Biju Patnaik University and Technology, Odisha (Sponsored by TEQIP-II, MHRD, Govt. of India). She has around eight years of research and teaching experience. She is a Fellow recipient of Eurasian Academy of Environmental Sciences (FEAES) and Society of Innovative Educationalist & Scientific Research Professional (FSIESRP).Her area of research focuses on fermentation technologies and waste management strategies. Her specific area of research includes conversion of lignocellulosic biomasses into bioenergy using various fermentation techniques. She has guided 07 M.Tech student and 20 B. Tech students for their dissertation work in the field of Microbial Fermentation and Environmental Technology. She has received various national and international awards for excellence in research and teaching. She has published 19 research articles in reputed international journals along with 10 book chapters. She has also filled an Indian patent and a Philippine patent in the field of industrial waste utilisation for value added products. She has also co-authored 3books that have been published by Springer Nature, CRC Press and Apple Publications.

Affiliations and expertise

Assistant Professor in the Department of Biotechnology at Odisha University of Technology and Research

Swagat Kumar Das

Swagat Kumar Das, is currently working as an Assistant Professor in the Department of Biotechnology at Odisha University of Technology and Research, (Formerly College of Engineering and Technology) Bhubaneswar, Odisha, India. He obtained his B.Pharm degree from BPUT, Rourkela; M.Tech Biotechnology degree from Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal and Ph.D. degree from Ravenshaw University, Cuttack, India. He is a Fellow recipient of Eurasian Academy of Environmental Sciences (FEAES) and Society of Innovative Educationalist & Scientific Research Professional (FSIESRP). He has more than 11 years of research and teaching experience. His research interests include: phytochemical screening and bioactivity studies leading to possible drug development from mangrove plants for treatment of diabetes and oxidative stress associated complications. His post PhD research area also focused on green synthesis of nanoparticles and evaluation of their pharmacological potentials. He has guided 8 M.Tech and 25 B.Tech students for their dissertation work. He has published more than 26 publications in various National and International journals and 9 book chapters. He has co-authored three books on Practical Biotechnology (I.K. International Publications), Practical Pharmacological Biotechnology (Springer) and Practical Environmental Biotechnology (Springer) and two edited books in Springer and Apple Academic Press

Affiliations and expertise

Assistant Professor in the Department of Biotechnology at Odisha University of Technology and Research, Odisha, India