Inflammatory Disorders - Part A, Volume 119

1. Using evasins to target the chemokine network in inflammation
Shoumo Bhattacharya and Akane Kawamura
2. Biological functions and clinical implications of interleukin-34 in inflammatory diseases
Yun Ge, Man Huang, Xiao-mei Zhu, and Yong-ming Yao
3. Pattern recognition receptors as potential drug targets in inflammatory disorders
Declan P. McKernan
4. Glycosylation changes in inflammatory diseases
Sophie Groux-Degroote, Sumeyye Cavdarli, Kenji Uchimura, Fabrice Allain, and Philippe Delannoy
5. Inflammatory bowel disease and targeted oral anti-TNFa therapy
Owen R. Griffiths, John Landon, Ruth E. Coxon, Keith Morris, Philip James, and Rachel Adams
6. Interplay between inflammation and cancer
Rekha Khandia and Ashok Munjal
7. Microglial NLRP3 inflammasome activation in multiple sclerosis
Melis Olcum, Bora Tastan, Cagla Kiser, Sermin Genc and Kursad Genc
8. Sleep deprivation, oxidative stress and inflammation
Fatin Atrooz and Samina Salim

Inflammation is a biological response triggered by different stimuli that has in the body a potentially damaging effect. In certain conditions, such as injury or infection, inflammation is a normal, healthy response. However, inflammatory disorders that result in the immune system attacking the body’s own cells or tissues may cause abnormal inflammation, which results in chronic pain, redness, swelling, stiffness, and damage to normal tissues. Mechanisms involved in promoting a number of different inflammatory disorders and their targeting for therapeutic benefit have been one of the hottest topics in last few decades. The two consecutive volumes (119 and 120) dedicated to this subject cover a wide spectrum of inflammatory disorders, mechanisms that are believed to cause them and different strategies for managing the inflammatory diseases.

• The volume integrates methods for studying inflammatory disorders, mechanisms that trigger these disorders and strategies for managing the inflammatory disorders
• It contains timely chapters written by well-renown authorities in their field
• The information provided in the volume is well supported by a number of high-quality illustrations, figures and tables, and targets a very wide audience of specialists, researchers and students

Protein chemists, biochemists, molecular cell biologists, immunologists, medical doctors, pharmacists, pharmacologists, medicinal chemists, structural biologists, computational biochemists, and other researchers working in the field of inflammation and inflammatory disorders/diseases