COVID-19 Update: We are currently shipping orders daily. However, due to transit disruptions in some geographies, deliveries may be delayed. To provide all customers with timely access to content, we are offering 50% off Science and Technology Print & eBook bundle options. Terms & conditions.
In Vivo Models to Study Angiogenesis - 1st Edition - ISBN: 9780128140208, 9780128140215

In Vivo Models to Study Angiogenesis

1st Edition

Author: Domenico Ribatti
Paperback ISBN: 9780128140208
eBook ISBN: 9780128140215
Imprint: Academic Press
Published Date: 18th August 2017
Page Count: 112
Sales tax will be calculated at check-out Price includes VAT/GST
111.77
73.95
62.95
79.95
63.96
Unavailable
Price includes VAT/GST

Institutional Subscription

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.

Description

In Vivo Models to Study Angiogenesis provides the latest information and an overview of the most common assays for studying angiogenesis in vivo. Under physiological conditions, angiogenesis is tightly controlled, whereas increased production of angiogenic stimuli and/or reduced production of angiogenic inhibitors leads to abnormal neovascularization, such as occurs in cancer, chronic inflammatory disease, diabetic retinopathy, macular degeneration and cardiovascular disorders. Several genetic and epigenetic mechanisms are involved in the early development of the vascular system. This book presents the latest information from the extensive literature and research available.

Evidence is now emerging that blood vessels themselves have the ability to provide instructive regulatory signals to surrounding non-vascular target cells during organ development. Thus, endothelial cell signaling is currently believed to promote fundamental cues for cell fate specification, embryo patterning, organ differentiation and postnatal tissue remodeling.

Key Features

  • Provides information on the most common assays to study angiogenesis in vivo
  • Presents an ideal reference for those interested in angiogenesis as a normal and vital process in growth and development
  • Covers wound healing, the formation of granulation tissue, and the transition of tumors from benign to malignant

Readership

Researchers and postgraduates working on angiogenesis, tissue engineering, oncology-- particularly early-career and PhD-level researchers

Table of Contents

The chorioallantoic membrane
The corneal micropocket assay
The zebrafish embryo
The sponge implant method
The Matrigen implant assay
In vivo gene transfer with AAV vectors
In vivo tumor models

Details

No. of pages:
112
Language:
English
Copyright:
© Academic Press 2017
Published:
18th August 2017
Imprint:
Academic Press
Paperback ISBN:
9780128140208
eBook ISBN:
9780128140215

About the Author

Domenico Ribatti

Domenico Ribatti is Professor of Human Anatomy, in the Department of Basic Biomedical Sciences, Neurosciences and Sensory Organs, Section of Human Anatomy and Histology, University of Bari Medical School, Italy. He was awarded his M.D. degree in 1981, with full marks. In 1983, he joined the Medical School as Assistant at the Institute of Human Anatomy, University of Bari. In 1984, he took the specialization in Allergology. In 1989, he spent one year in Geneva, working at the Department of Morphology. In 2008, he received the honoris causa degree in Medicine and Pharmacy form the University of Timisoara, Romania. He is the author of over 800 publications and 50 chapters, as well as a number of books for Elsevier/Academic Press including: Milestones in Immunology (2017) In Vivo Models to Study Angiogenesis (2017) Immunology in the Twentieth Century (2018) Tumor Vascularization (2020) Tumor Microenvironment Regulation of Tumor Expansion (2021) .

Affiliations and Expertise

Professor of Human Anatomy, Department of Basic Biomedical Sciences, Neurosciences and Sensory Organs, Section of Human Anatomy and Histology, University of Bari Medical School, Bari, Italy

Ratings and Reviews