Contents. List of Contributors. Preface (I.L. Cartwright). A Perspective on In Vivo Footprinting (M. Nenoi and I.L. Cartwright). Genomic Sequencing by Template Purification: Principles and mapping of Protein-Bound and Single-Stranded Sequences in Vivo (J. Mirkowitch). Polymerase Chain Reaction-Aided Genomic Footprinting: Principles and Application (A.D. Riggs and G.P. Pfeifer). In Vivo Footprinting of the Interaction of Proteins with DNA and RNA (T. Grange, G. Rigaud, E. Bertrand, M. Fromont-Racine, M.L. Espinals, J. Roux, and R. Pictet). Characterization of In Vivo DNA-Protein Interactions in the Transcriptional Regulation of the Human Heat Shock Genes (L. Sistonen and R.I. Morimoto). Analysis of the Gata-1 Gene Promoter and Globin Locus Control Region Elements by In Vivo Footprinting 9E.C. Strauss and S.H. Orkin). Anazlyzing Hormone Regulation of Transcription by Genomic Footprinting (A. Reik, G. Schutz and A.F. Stewart). Photofootprinting Studies of SV40 Minichromosomes In Vivo (G.A. Grossman and M.M. Becker). Index.