
Improving the Therapeutic Ratio in Head and Neck Cancer
Description
Key Features
- Provides key scientific background for clinicians when developing novel clinical trials and important examples for basic scientists of the types of work required to move a concept from the lab to the clinic
- Presents consistent pathway diagrams in each chapter, thus making it easier to understand complicated pathways
- Includes chapter summaries of the critical next steps needed to move studies from their current state into practice changing clinical data
Readership
Cancer researchers; oncologists; graduate students
Table of Contents
1. Overview of head and neck cancer management
2. The role of immunotherapy and molecularly targeted therapies in head and neck cancer
3. Targeting the PI3K/mTOR pathway
4. Autophagy inhibition to sensitize HNC to radiation and chemotherapy
5. Overcoming head and neck cancer stem cells
6. TAM Family proteins and therapy resistance
7. Eph/Ephrin family proteins and theapy resistance
8. Metabolic reprogramming to modulate therapeutic sensitivity
9. FGFR and cMET
10. Targeting GPCRs in HNC
11. Improving the response to immunotherapy
12. Chk1/2 inhibition in radiation and cetuximab resistance
Product details
- No. of pages: 376
- Language: English
- Copyright: © Academic Press 2019
- Published: October 4, 2019
- Imprint: Academic Press
- Hardcover ISBN: 9780128178683
- eBook ISBN: 9780128178690
About the Series Editor
Benjamin Bonavida
Affiliations and Expertise
About the Series Volume Editor
Randall Kimple
Affiliations and Expertise
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