Description

This book provides an in-depth insight and overview of a number of most promising immunopotentiators in modern vaccines. In contrast to existing books on the subject it provides recent data on the critical mechanisms governing the activity of vaccine adjuvants and delivery systems. Knowledge of immunological pathways and scenarios of the cells and molecules involved is described and depicted in comprehensive illustrations.

Key Features

* Contributions from leading international authorities in the field * Well-illustrated, informative figures present the interactions between immunopotentiators and the host immune system * Each chapter lists advantages and potential hurdles for achieving a practical application for the specific immunopentiator

Readership

Immunologists, virologists, microbiologists, oncologists, neuroscientists, and academics working in vaccinology

Table of Contents

Perspective on Immunological mechanisms underlying adjuvant activity Host-derived immunopotentiators Natural and synthetic immunopotentiators Particulate immunopotentiators and delivery systems Mucosal/ non-parenteral adjuvants Th-1/ CTL adjuvants Adjuvants in non-infectious disease vaccines Clinical Practice

Details

No. of pages:
384
Language:
English
Copyright:
© 2006
Published:
Imprint:
Academic Press
Electronic ISBN:
9780080457215
Print ISBN:
9780120884032

About the editors

Virgil Schijns

Dr. Virgil E.J.C. Schijns is special guest Professor in Cell Biology & Immunology group, Wageningen University, 6708 WD Wageningen, The Netherlands. Dr. Schijns received his Ph.D. degree at Utrecht University in 1990. Recent professional appointments are Chief Scientific Officer at ERC in Belgium and The Netherlands, (2011 to present); Chief Technology Officer, Vice-president at a small biotech spin-off from Utrecht University (2008 to 2011); Special professor immune Intervention, Wageningen University and Research center (2008 to present); Special Professor in Immunology and Virology at North Carolina State University (NCSU), Raleigh. Department of Population Health and Pathobiology (2002 to present) and Head of Department for Vaccine Technology and Immunology (VTI), AKZO NOBEL (1999 to 2008).

About the author

Virgil Schijns

Dr. Virgil E.J.C. Schijns is special guest Professor in Cell Biology & Immunology group, Wageningen University, 6708 WD Wageningen, The Netherlands. Dr. Schijns received his Ph.D. degree at Utrecht University in 1990. Recent professional appointments are Chief Scientific Officer at ERC in Belgium and The Netherlands, (2011 to present); Chief Technology Officer, Vice-president at a small biotech spin-off from Utrecht University (2008 to 2011); Special professor immune Intervention, Wageningen University and Research center (2008 to present); Special Professor in Immunology and Virology at North Carolina State University (NCSU), Raleigh. Department of Population Health and Pathobiology (2002 to present) and Head of Department for Vaccine Technology and Immunology (VTI), AKZO NOBEL (1999 to 2008).