Immunopharmacology

Immunopharmacology is the 11th volume of the proceedings of the Third International Pharmacological Meeting held at Sao Paulo, Brazil on July 26, 1966. The volume covers papers that deal with immunoglobulins responsible for hypersensitivity reactions and with the mechanisms of these reactions; pharmacological mediators of immediate and delayed hypersensitivity; Arthus reactions; and soluble factors released by the action of antigen on sensitized lymphocytes. The book concludes with a single paper on the subject of penicillin allergy. Immunologists and pharmacologists will find the volume invaluable.

List of Authors Preface I. Immunoglobulins and Mechanisms Properties of Immunoglobulins which Mediate the Release of Vasoactive Amines in Experimental Animals Discussion The Mechanism of Passive Sensitization in PCA and RPCA in Guinea Pigs Discussion Molecular Bases for Biologic Activities of Antigen-Antibody Complexes and Aggregated γ-Globulin Interaction of Antibody with Guinea Pig Lung In Vitro Mechanism of the Anaphylactic Reaction Discussion II. Mediators The Probable Role of Known Mediators in Hypersensitivity Reactions Discussion Mode of Binding, Release and Uptake of Histamine in Isolated Mast Cell Granules Discussion Role of Anaphylatoxin and of Bradykinin in Passive Cutaneous Anaphylaxis against Heterologous Precipitating Antibody in the Rat A Permeability Factor in the Vascular Arthus Reaction Mediators in Delayed Hypersensitivity Transfert In Vitro de l'Hypersensibilité Retardée par un Facteur Cellulaire Diffusible Discussion Delayed Hypersensitivity In Vitro Discussion The Role of Complement in the Attraction of Polymorphonuclear Leukocytes to Immune Reactants III. Drug Allergy Immunochemical Mechanisms of Drug Allergy Index