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Immunopharmacology of Macrophages and Other Antigen-Presenting Cells - 1st Edition - ISBN: 9780121378004, 9780080917122

Immunopharmacology of Macrophages and Other Antigen-Presenting Cells

1st Edition

Series Editors: Elisabeth Hoefsmit Clive Page
Series Volume Editor: Carla Bruijnzeel-Koomen
Hardcover ISBN: 9780121378004
Imprint: Academic Press
Published Date: 14th April 1994
Page Count: 208
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Table of Contents

R.H.J. Beelen and E.W.A. Kamperdijk, Macrophages: General Aspects.
A.A. te Velde, Interaction Between Cytokines and Monotcytes/Macrophages.
T. Thepen and C.E.G. Havenith, Functions of Alveolar Macrophages.
E.W.A. Kamperdijk, E. van Vugt, C.D. Richters, and R.H.J. Beelen, Morphology of Dendritic Cells.
D.N.J. Hart and V.L. Calder, Human Dendritic Cells: Function and Cytokine Production.
G.C. Mudde, W. Fokkens, C.A.F.M. Bruijnzeel-Koomen, Dendritic Cells in Atopic Disease.
P.G. Holt, The Role of Dendritic Cells in Immune Defence of the Airways.
W. Allaerts and H.A. Drexhage, Dendritic Cells in Autoimmune Disease.
J.A. Roake and J.M. Austyn, The Role of Dendritic Cells in Transplantation.
M.S. Roberts, and S.C. Knight, Cyclosporin and Antigen-Presenting Cell Function.


The consequences for diseases involving the immune system such as AIDS, and chronic inflammatory diseases such as bronchial asthma, rheumatoid arthritis, and atherosclerosis, now account for a considerable economic burden to governments worldwide. In response there has been an enormous research effort investigating the basic mechanisms underlying such diseases, and a tremendous drive to identify novel therapeutic applications for their prevention and treatment. Though a plethora of immunological studies have been published in recent years, little has been written about the implications of such research for drug development. As a consequence, this area has not gained the prominence of other new fields such as molecular pharmacology or neuropharmacology, and a focal information source for the many pharmacologists interested in diseases of the immune system remains unpublished.
The Handbook of Immunopharmacology Series provides such a source through the commissioning of a comprehensive collection of volumes on all aspects of immunopharmacology. Editors have been sought after for each volume who are not only active in their respective areas of expertise, but who also have a distinctly pharmacological bias to their research.
The Series follows three main themes, each represented by volumes on individual component topics. The first covers each of the major cell types and classes of inflammatory mediators ("cells and mediators"). The second covers each of the major organ systems and the diseases involving the immune and inflammatory responses that can affect them ("systems"). The third covers different classes of drugs currently used to treat these diseases as well as those under development ("drugs").


Research-level pharmacologists and as a reference work in this area for those involved in degree-level teaching.
A Publication of Academic Press U.K.


No. of pages:
© Academic Press 1994
14th April 1994
Academic Press
Hardcover ISBN:


@qu:"This volume highlights the important role of macrophages and other antigen-presenting cells in the initiation and modulation of immune responses. Special emphasis has been given to the role of these cells in human diseases and to the cytokine network which affects their influence on immune response."

Ratings and Reviews

About the Series Editors

Elisabeth Hoefsmit

Affiliations and Expertise

Vrje Universiteit, Amsterdam, The Netherlands

Clive Page

Professor Clive P. Page, BSc PhD OBE HonFBPhS is a Professor of Pharmacology, King’s College London and Director of the Sackler Institute of Pulmonary Pharmacology, King’s College London. Clive’s main research interests are in the pharmacology of inflammation and respiratory disease and he has published over 250 scientific papers. Clive was the co-founder and previous Chairman of the Board of Verona Pharma plc, an AIM listed Company developing new drugs for the treatment of Respiratory Diseases. He is a Non Executive Director of and on boards of several companies. He was awarded the Society of Biology President’s Medal in 2012 for an outstanding contribution to the life sciences over the previous year. He is a Fellow of the Royal Society of Biology and an Honorary Fellow and President Elect of the British Pharmacological Society. In 2017, Clive was awarded an OBE for Services to Pharmacology.

Affiliations and Expertise

BSc PhD OBE HonFBPhS, Professor of Pharmacology, King’s College London Director, Sackler Institute of Pulmonary Pharmacology, King’s College London

About the Series Volume Editor

Carla Bruijnzeel-Koomen

Affiliations and Expertise

University Hospital, Utrecht, The Netherlands