Immunomodulation in Domestic Food Animals

Immunomodulation in Domestic Food Animals

Advances in Veterinary Science and Comparative Medicine

1st Edition - November 28, 1990

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  • Editor: Bernald Charley
  • eBook ISBN: 9780323154888

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Description

Immunomodulation in Domestic Food Animals covers the developments in the immunology and regulation of the immune response in domestic food animals. This book is organized into four parts encompassing 12 chapters that describe numerous factors affecting an immune response of animals and the management of these factors for food animal production. Part I provides an overview of the basic concepts of immunomodulation and the rationale for manipulating the immune response in food animals. Part II contains information on immunopotentiation using chemicals and a thorough discussion of adjuvant use. The molecular biology and in vivo use of cytokines in food animals is presented in Part III. Lastly, Part IV discusses physiologically regulated immunomodulation, including nutritional modulation of the immune response and neuroendocrine-immune interactions. This book is of great value to immunologists, microbiologists, and feed scientists and researchers.

Table of Contents


  • Contributors

    Foreword

    Preface

    Part I: Introduction

    Rationale for Using Immunopotentiators in Domestic Food Animals

    I. Introduction

    II. Why Are Immunomodulators Needed?

    ΙII. Specific versus Nonspecific Immunomodulation

    IV. Summary

    References

    Model Systems to Study Immunomodulation in Domestic Food Animals

    I. Introduction

    II. Stress Models

    III. Glucocorticoid Immunosuppression Models

    IV. Infectious Disease Model Systems

    V. Summary

    References

    Mechanisms of Action of Some Immunomodulators Used in Veterinary Medicine

    I. Introduction

    II. Structure and Function of the Immune System

    III. Immunomodulation

    IV. Physiologically Important Immunomodulators

    V. Synthetic Compounds with Immunomodulatory Activity

    VI. Microbial Products as Immunomodulators

    VII. Liposomes

    VIII. Concluding Comments

    References

    Part II: Chemical Immunomodulation

    Chemically Induced Immunomodulation in Domestic Food Animals

    I. Introduction

    II. Chemin Immunomodulation in Domestic Food Animal Species

    ΙII. Chemical Immunomodulators Which Have Apparently Not Been Evaluated in Domestic Food Animals

    IV. Summary

    References

    Classical and New Approaches to Adjuvant Use in Domestic Food Animals

    I. Introduction

    II. Aluminum Salts

    ΙII. Oil Emulsions

    IV. Surface Active Agents

    V. ISCOMS

    VI. Muramyldipeptides

    VII. Polymeric Adjuvants

    VIII. General Conclusions

    References

    A Thymosin-Tuftsin Conjugate as a New Potential Immunomodulator in Cattle

    I. Introduction

    II. Tuftsin: A Macrophage Activator

    ΙII. Thymosin-α: A Τ Cell Activator

    IV. Thymosin-Tuftsin Conjugate (IMP-1)

    V. Conclusion

    References

    Part III: Cytokine Immunomodulation

    The Molecular Biology of Large Animal Cytokines

    I. Cytokine Biology

    II. Recombinant Bovine and Porcine Cytokines

    ΙII. Conclusions

    References

    Interferon Immunomodulation in Domestic Food Animals

    I. Introduction

    II. Modulation of Nonspecific Antimicrobial Defense Mechanisms

    ΙII. Modulation of the Specific Cellular Immune Response

    IV. Enhancement of Antimicrobial Mechanisms in the Gut

    V. Immunoenhancement in Noninfectious Diseases

    VI. Concluding Remarks

    References

    In Vivo Use of Interleukins in Domestic Food Animals

    I. Introduction

    II. Rationale for Using Interleukins in Domestic Food Animals

    ΙII. In Vivo Studies with Interleukins in Domestic Food Animals

    IV. Conclusions and Prospects

    References

    Part IV: Physiologically Regulated Immunomodulation

    Nutritional Modulation of Immunity in Domestic Food Animals

    I. Introduction

    II. Protein and Energy

    ΙII. Fat-Soluble Vitamins

    IV. Water-Soluble Vitamins

    V. Minerals

    VI. Conclusion

    References

    Neuroendocrine-Immune Interactions

    I. Introduction

    II. Characteristics of the Neuroendocrine-Immune System

    ΙII. Conclusions

    References

    Potential for Improving Animal Health by Modulation of Behavior and Immune Function

    I. Introduction

    II. Behavior of Farm Animals

    ΙII. Social Behavior and Immune Function

    IV. Nonsocial Behaviors and Immune Function

    V. Brain-Immune Interactions

    VI. Concluding Remarks

    References

    Index




Product details

  • No. of pages: 348
  • Language: English
  • Copyright: © Academic Press 1990
  • Published: November 28, 1990
  • Imprint: Academic Press
  • eBook ISBN: 9780323154888

About the Editor

Bernald Charley

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