Immunology of Infection

Immunology of Infection

3rd Edition - September 23, 2010

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  • Editors: Stefan Kaufmann, Dieter Kabelitz
  • eBook ISBN: 9780080951232
  • Hardcover ISBN: 9780123748423

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Description

Immunology of Infection, 3e, edited by two leading experts in the field, presents the most appropriate up-to-date experimental approaches in the detail required for modern microbiological research. Focusing on the methods most useful for the microbiologist interested in analyzing host-pathogen relationships, this volume will be essential reading for all researchers working in microbiology, immunology, virology, mycology and parasitology. This new edition of Immunology of Infection provides ready-to-use "recipes" and the latest emerging techniques as well as novel approaches to the tried and tested, established methods included in the successful first edition. Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Established for over 30 years, Methods in Microbiology will continue to provide you with tried and tested, cutting-edge protocols to directly benefit your research.

Readership

Microbiologists, immunologists, virologists, mycologists, and parasitologists

Table of Contents

  • I. General Methods
    Radbruch A - Phenotyping and isolation of functionally distinct leukocyte populations; Schütze S - Magnetic isolation of subcellular compartments; Berzofsky J - Prediction of MHC ligands and T-cell epitopes; McMichael A - Quantitative analysis of T-cell responses; Schurr E - Genetics of susceptibility and resistance to infection; Wiker H - Proteomic approaches to study immunity in infection; Sioud M - siRNA as a tool to study immune responses in infection; Schröder JM - Isolation and characterization of antimicrobial peptides; Karin M - Toll - and NOD-like receptors in anti-infective immunity; von Andrian UH - Visualization of immune responses in vivo

    II. Murine Models
    A. In vitro analysis
    Czuprynski CJ - Isolation of lymphocytes from infected animals; Busch DH - Killer cell assays; Kiyono H - Quantification of murine T-cell cytokine responses; Gordon S - Isolation and functional charactzerization of macrophages

    B. In vivo analysis
    Ehlers S - Measuring immune responses in vivo; Belkaid Y - Control of infection by regulatory T-cells; Stockinger B - Th17 cells in inflammation

    C. Specific Models
    Orme IM - Murine models of tuberculosis; Muller I - The leishmaniasis model; Autenrieth IB - Murine models of infection with extracellular bacteria; Flynn JL - Local immune responses in the lung; Romani L - Murine models of fungal infections; Powrie F - Immunity in the gut; Reddehase MJ - Murine cytomegalovirus infection; Lingnau K/von Gabain A - Boosting of immune responses by adjuvants

    III. Human System
    Banchereau J - Subpopulations of human dendritic cells; Yssel H - Measuring human cytokine responses; Seitzer U - Measuring immune responses in situ; Garcia JV - Humanized mice for the analysis of human immune responses

    IV. Appendix
    Benoist C - The NIH knock-out mouse project; Beutler B - Forward genetic analysis to understand innate immunity

Product details

  • No. of pages: 544
  • Language: English
  • Copyright: © Academic Press 2010
  • Published: September 23, 2010
  • Imprint: Academic Press
  • eBook ISBN: 9780080951232
  • Hardcover ISBN: 9780123748423

About the Series Volume Editors

Stefan Kaufmann

Affiliations and Expertise

Max Planck Institute for Infection Biology, Berlin, Germany

Dieter Kabelitz

Dieter Kabelitz is full professor at the University of Kiel, Germany, and Director of the Institute of Immunology. Dieter Kabelitz studied medicine in Freiburg and Munich, Germany. He was a post-doc in Uppsala/Sweden and at Rockefeller University, New York. In 1988, he was appointed Associate Professor for Cellular Immunology at the University of Heidelberg. From 1992 to 1999 he was Head of the Department of Immunology at the Paul-Ehrlich Institute in Langen, Germany. Since 1999 he is a full professor at the University of Kiel and Director of the Institute of Immunology. His scientific expertise is in the field of the functional characterization of human T cells with a special focus on  T cells. Current projects aim to explore the potential of human  T cells for the immunotherapy of cancer. He has published more than 360 papers listed in PubMed/Medline. Dieter Kabelitz was chairman of the Collaborative Research Center (SFB) 415 „Specificity and Pathophysiology of Signal Transduction Pathways“ funded at Kiel University by the German Research Foundation (DFG). He is a founding member and member of the Steering Committee of the DFG-funded Cluster of Excellence „Inflammation-at-Interfaces“. He was President of the German Society for Immunology (DGfI) in 2011 and 2012, and he is a Council member of the International Union of Immunological Societies (IUIS) and chair of the Education Committee (EDU) of IUIS.

Affiliations and Expertise

Institute of Immunology, Christian-Albrechts-University, Kiel, Germany

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