Immunological Implications and Molecular Diagnostics of Genitourinary Cancer

Immunological Implications and Molecular Diagnostics of Genitourinary Cancer

1st Edition - September 1, 2022

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  • Editor: Moulay Ennaji
  • Paperback ISBN: 9780323854962

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Description

Immunological Implications and Molecular Diagnostics of Genitourinary Cancer updates on recent accomplishments, unifying concepts, and future challenges in the study of tumor-associated immune cells, emphasizing genitourinary cancers. The presence of inflammatory immune cells in human tumors raise a fundamental question: How do cancer cells avoid destruction by immune attack? In principle, tumor development can be controlled by cytotoxic innate and adaptive immune cells, however, as tumors develop from neoplastic tissue to clinically detectable tumors, cancer cells evolve different mechanisms. This book covers research on the immunological implications of genitourinary cancer with a comprehensive view, especially surrounding diagnosis and cellular mechanisms.

Key Features

  • Discusses the impact of the immune system on the initiation, progression and treatment of cancer
  • Provides insights on the important role of the suppressor genes and oncogenes in genitourinary cancers
  • Shows the advantages of combining clinical issues of urologic cancers with immunological techniques, like immunohistochemistry and immunofluorescence
  • Demonstrates the implications genitourinary cancer has on the human innate immune system

Readership

Researchers in immunological and molecular characterization and implications of genitourinary cancer, immunologists, molecular biologists, oncologist, applied microbiologists. Students in immunology, molecular biology and cancers, oncology, virology and metabolism research

Table of Contents

  • 1. Gene suppressor and oncogenes
    2. Implication of growth factor's genes in genitourinary cancers
    3. Cytokines genes alterations
    4. Proteomic analysis
    5. Genetic diagnostics and prognostic biomarkers
    6. Exosomes as diagnostic and prognostic tool
    7. Metabolism defects
    8. Clinical genomic relevance
    9. Recent advances of immunotherapy
    10. Modern therapeutic targets

Product details

  • No. of pages: 516
  • Language: English
  • Copyright: © Academic Press 2022
  • Published: September 1, 2022
  • Imprint: Academic Press
  • Paperback ISBN: 9780323854962

About the Editor

Moulay Ennaji

Dr. Moulay Mustapha Ennaji, Professor in Virology and Oncology at the University of Casablanca and Director of the Quality and Medical Biotechnologies Team at Laboratory of Virology Microbiology, Quality, Biotechnologies/Eco-Toxicology and Biodiversity, Faculty of Sciences and Techniques, Hassan II University Mohammedia of Casablanca, Morocco Prof. Dr. Moulay Mustapha Ennaji is a Moroccan and Canadian citizen and native of Marrakesh (Morocco). He is a scientist specializing in the fields of virology, hygiene, and microbiology and currently a Professor in Virology and Oncology at the University of Casablanca, and Since 2010, he has been the Director of the Quality and Medical Biotechnologies Team at the Laboratory of Virology Microbiology, Quality, Biotechnologies. He leads the Virology Oncology and Medical Biotechnology Team is and Deputy Director of the Research Centre of Natural Resources and Food (rensa) of UH2C. He has also been responsible for the master programs in biotechnology and biomedical technologies (2003), DESA of Microbiology and Bioengineering (2005-2010), Masters of Science and Technology in Microbiology, Applied Virology and Bio-industry Engineering, and MST of Livings in Immuno-Virology and Applied Microbiology (2010 to 2015). He received a MSc in 1986 and a PhD in virology in 1993 from Armand Frappier Institute, University of Quebec (Canada). Between 1991 and 1993 he completed a post doctorate at the Canadian Red Cross. From 1993 to 1995, he was a research associate (RA) and from 1995 to 1996 and a research officer (RO) at the National Council of Research of Canada (CNRC). He was also a visiting researcher at the University of California, Irvine in the United States and a lecturer at the Histochemistry Institutes of Paris (France). He was a guest researcher of the Franklin AU:1 Foundation in USA NIH Bethesda. He has published 61 journals articles and is an editorial board member of the journal, Infectious Agents and Cancer. As a scientist concerned with research development, he had been given numerous lectures in virology, cancerology, hygiene, and microbiology since 1986 at many Moroccan, Canadian, and American universities. Throughout his career, Dr. Ennaji has been rewarded 24 awards. He has organized numerous national and international meetings in the fields of virology, microbiology, and hygiene. At present, he is the vice president of the three Moroccan societies of Biosafety, Cancer, and Microbiology.

Affiliations and Expertise

Professor, Virology and Oncology, University of Casablanca, Morocco; Director, Quality and Medical Biotechnologies Team, Laboratory of Virology Microbiology, Quality, Biotechnologies/Eco-Toxicology and Biodiversity; Faculty, Sciences and Techniques, Hassan II University Mohammedia of Casablanca, Morocco

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