Immunochemical Techniques, Part M: Chemotaxis and Inflammation, Volume 163

1st Edition

Serial Volume Editors: Giovanni Di Sabato
Editor-in-Chiefs: John Abelson Melvin Simon
Hardcover ISBN: 9780121820640
eBook ISBN: 9780080882802
Imprint: Academic Press
Published Date: 28th November 1988
Page Count: 819


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Table of Contents

Methods for the Study of the Biochemistry of Inflammation. A.P. Kaplan and M. Silverberg, Mediators of Inflammation: An Overview. M. Di Rosa, L. Sautebin, and R. Carnuccio, Phospholipase A2, Lipocortins, and Antiphospholipase Proteins. P.F. Weller, Human Eosinophil Lysophospholipase. R.L. Wykle, J.T. O'Flaherty, and M.J. Thomas, Platelet-Activating Factor. K. Fujikawa, Bovine Hageman Factor and Its Fragments. M. Silverberg and A.P. Kaplan, Human Hageman Factor and Its Fragments. G. Dooijewaard, C. Kluft, and J.J.L. van Iersel, Measurement of Contact-Activation Patterns of Human Plasma Samples with Synthetic Substrates. M. Silverberg and A.P. Kaplan, Prekallikrein. J. Spragg, Latent Kallikrein from Human Urine. R. Geiger and W. Miska, Human Tissue Kallikrein. G.S. Bailey, Rat Pancreas Kallikrein. J. Chao and L. Chao, Rat Urinary Kallikrein. T. Berg, Immunochemical Viewing of Kallikrein in Tissues. J.W. Ryan, Use of 125I- Labeled Aprotinin in the Assay of Glandular Kallikreins. C. Kluft, Synthetic Substrates for the Assay of Prekallikrein and Factor XII. M. Schapira, A. de Agostini, and R.W. Colman, Cae1 Inhibitor: The Predominant Inhibitor of Plasma Kallikrein. J.W. Ryan, Arginine Carboxypeptidase and Its Inhibitors. J.W. Ryan, Angiotensin-Converting Enzyme, Dipeptidyl Carboxypeptidase I, and Its Inhibitors. D. Regoli and J. Barabaae, Kinin Receptors. N. Kitamura, H. Nawa, Y. Takagaki, S. Furuto-Kato, and S. Nakanishi, Cloning of cDNAs and Genomic DNAs for High-Molecular-Weight and Low-Molecular-Weight Kininogens. W. M ller-Esterl, D.A. Johnson, G. Salvesen, and A.J. Barrett, Human Kininogens. F. Fiedler and R. Geiger, Separation of Kinins by High-Performance Liquid Chromatography. G. Drapeau and D. Regoli, Synthesis of Bradykinin Analogs. L.M. Greenbaum and H. Okamoto, T-Kinin and T-Kininogen. J. Barabe and D. Regoli, Kinin Antagonists. D.J. Loskutoff and R.R. Schleef, Plasminogen Activators and Their Inhibitors. J.H. Verheijen, Tissue-Type Plasminogen Activator a


FROM THE PREFACE: Chemotaxis and inflammation, like as other biological processes, can be divided into humoral and cellular components. In this simplest sense soluble activators or mediators of host or external origin interact with cells that respond to signals received and transmitted via specific membrane receptors. The biological consequences are dramatic, and the biochemical mechanisms are complex and interrelated through a series of cascades that may involve several chemical messengers of different chemical classes. Volumes 162 and 163 of Methods in Enzymology cover in Vitro and in Vivo methodology that has been developed for the purpose of studying the biochemistry of these active humoral factors and the biology of the cells and their receptors that respond to the various signals....The literature dealing with chemotaxis and inflammation is extensive and new techniques are constantly being developed. Therefore, some selection has been necessary to include the most commonly used and generally applicable techniques. Newer methods often involve significant modifications of established procedures, and these innovations have been included.


Biochemists, immunologists, microbiologists, pharmacologists, toxicologists, physiologists, clinical chemists, cell and molecular biologists, and biomedical scientists.


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© Academic Press 1988
Academic Press
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About the Serial Volume Editors

Giovanni Di Sabato Serial Volume Editor

Affiliations and Expertise

Vanderbilt University, Nashville, Tennessee, U.S.A.

About the Editor-in-Chiefs

John Abelson Editor-in-Chief

Affiliations and Expertise

California Institute of Technology, Division of Biology, Pasadena, U.S.A.

Melvin Simon Editor-in-Chief

Affiliations and Expertise

The Salk Institute, La Jolla, CA, USA