Immunobiology of Transfer Factor - 1st Edition - ISBN: 9780124098503, 9781483277684

Immunobiology of Transfer Factor

1st Edition

Editors: Charles H. Kirkpatrick Denis R. Burger H. Sherwood Lawrence
eBook ISBN: 9781483277684
Imprint: Academic Press
Published Date: 1st January 1983
Page Count: 462
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Description

Immunobiology of Transfer Factor compiles research papers presented at the Fourth International Transfer Factor Workshop, held at the Given Institute of Pathobiology in Aspen, Colorado, on October 3-6, 1982.

This book focuses on the immunologic effects of transfer factor, which are supported by in vitro and in vivo experiments that indicate immunologically specific interactions between transfer factor and antigens. The topics include the selective removal of transfer factor activity with antigen, antigen-specific suppressor factor in human leukocyte dialysates, and specific suppressor dialysates from mice. The kinetics of immune response and production of transfer factor in bovine, dialyzable leukocyte extracts in pulmonary diseases, and mechanisms of action of human transfer factor are also elaborated.

This compilation is suitable for microbiologists, immunologists, and specialists researching on transfer factor.

Table of Contents


Contributors


Preface


Acknowledgments


The Merrill W. Chase Prize in Cellular Immunology


Section I. The Nature of Transfer Factor


The Immunological Enigma of Transfer Factor


Human Transfer Factor: Specificity and Structural Models


Human Transfer Factor: Exogenous Labeling, Purification, and Role of Ribonucleic Acid Segment


Selective Removal of Transfer Factor Activity with Antigen


Antigen-Specific Inducer Factor in Human Leukocyte Dialysates: A Product of TH Cells which Binds to Anti-V Region and Anti-La Region Antibodies


Antigen-Specific Suppressor Factor in Human Leukocyte Dialysates: A Product of Ts Cells which Binds to Anti-V Region and Anti-La Region Antibodies


Isolation and Purification of Antigen-Specific Inducer and Suppressor Factors from Pooled Leukocyte Dialysates of Unselected Donors by Affinity Adsorption


Section II. Studies of Dialyzable Leukocyte Extracts in Animals


Dialyzable Leukocyte Extract Containing Transfer Factor—Its Future in Veterinary Medicine


Effect of Dialyzable Leucocyte Extract and Other Tissue Dialysates on Listeria Resistance


Osteosarcoma-Specific Dialyzable Extracts: Prophylaxis Post Surgery in an Animal Model of Human Osteosarcoma


Antigen-Specific Transfer Factor Induced in Mice by an Attenuated Virus from the Tick-Borne Encephalitis Complex: Biological, Histological, and Concentration Studies


Antigen-Specific Suppressor Factor in Human Leukocyte Dialysates Suppresses in Vivo Footpad Reactivity in Immunized BALB/c Mice


Specific Suppressor Dialysates from Mice


Kinetics of Immune Response and Production of Transer Factor in Bovine


Transfer of Cell-Mediated Immunity in Vitro to Human Lymphocytes Using Dialyzable Leukocyte Extracts from Immune Burros


Section III. Studies of

Details

No. of pages:
462
Language:
English
Copyright:
© Academic Press 1983
Published:
Imprint:
Academic Press
eBook ISBN:
9781483277684

About the Editor

Charles H. Kirkpatrick

Denis R. Burger

H. Sherwood Lawrence

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