Secure CheckoutPersonal information is secured with SSL technology.
Free ShippingFree global shipping
No minimum order.
During the last few years, immunoassay has gained tremendous popularity in clinical and research laboratories and has been applied to determine hormone, enzyme, protein, drug, and infectious agents. The aim of this book is to provide clinical laboratory personnel and students with an understanding of the principle of immunoassay and the production of reagents for immunoassay.
1. General Principle of Immunoassay
II. Theoretical Basis of Immunoassay
III. Optimization of Immunoassay
IV. Heterogeneous Immunoassay Systems
V. Homogeneous Immunoassay Systems
2. Production of Immunoassay Reagents
II. Receptors or Binders
III. Unlabeled Ligands—Calibrators
IV. Labeled Ligands and Receptors
V. Separation Techniques
3. Practical Guide to Immunoassay Method Evaluation
II. Protocol Outline
III. Establishing Objectives and Preparation
IV. Evaluation of Precision
V. Standard Curves
VIII. Evaluation of Accuracy
IX. Antibody Characteristics
X. Monitoring Reaction Conditions
XI. Clinical Validation
XII. Protocol Development: Summary
4. Clinical Validation of Immunoassays: A Well-Designed Approach to a Clinical Study
II. Elements of a Well-Designed Study
III. Choosing Decision Levels to Minimize Costs
IV. Relation of New Tests to Existing Tests
V. A Word about Normal Ranges
VII. Illustrative Example: Apolipoprotein A-I
Appendix: Preparation of ROC Curves
5. Data Reduction Techniques for Immunoassay
I. Purpose of Chapter
III. Interpolation Techniques of Data Reduction
IV. Models and Statistical Approaches to Data Reduction
V. Nonlinear Models in Immunoassay
Appendix A: BASIC Program to Fit Four Parameter Model to Data by Nonlinear Least Squares
Appendix B: BASIC Program for Point-to-Point Linear Interpolation
6. Immunoassays: Quality Control and Troubleshooting
Part A: Quality Control: A Simple, Cost-Effective Approach
II. Implementing a QC Program
III. Selection of Appropriate Curve Fits for Immunoassay Data
VI. Assay Conditions
VIII. Patient Samples
Part B: Troubleshooting Immunoassays: Where the Practical and Theoretical Meet
III. Reciprocal Plot
IV. Scatchard Analysis
- © Academic Press 1987
- 16th September 1987
- Academic Press
- eBook ISBN:
@qu:The emphasis has been placed on 'practical'...the chapter on clinical validation of immunoassays is excellent.
@qu:A valuable guide for clinical laboratory personnel and students.
@source:--EXPERIMENTAL AND CLINICAL PHARMACLOGY
Elsevier.com visitor survey
We are always looking for ways to improve customer experience on Elsevier.com.
We would like to ask you for a moment of your time to fill in a short questionnaire, at the end of your visit.
If you decide to participate, a new browser tab will open so you can complete the survey after you have completed your visit to this website.
Thanks in advance for your time.