Imaging in Movement Disorders

Imaging in Movement Disorders

Imaging Methodology and Applications in Parkinson's Disease

1st Edition - October 9, 2018

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  • Editor: Marios Politis
  • Hardcover ISBN: 9780128154182
  • eBook ISBN: 9780128154199

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Imaging Methodology and Applications in Parkinson's Disease, Volume 141, provides an up-to-date and comprehensive textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. Over the last decades, advances in neuroimaging tools has played a pivotal role in expanding our understanding of disease etiology and pathophysiology, identifying biomarkers to monitor disease progression, aiding differential diagnosis, and in the identification of novel targets for therapeutic intervention. This book brings together lessons learned from neuroimaging tools in movement disorders, including chapters on Advances in PET Methodology, Advances in MRI Methodology, Advances in SPECT Methodology, Hybrid PET/MRI Methodology, and more.

Key Features

  • Provides an up-to-date and comprehensive textbook addressing all aspects of neuroimaging in movement disorders
  • Offers a complete review of advances in core imaging methodology and the application of neuroimaging tools
  • Represents an indispensable educational and research reference of value to all movement disorder specialists, physicians, researchers and students


Specialists in Movement Disorder, Trainees in Movement Disorder, Neurologists, Researchers, Neuroimaging and Neuroscience Scientists, Medical Students, Universities

Table of Contents

  • Section 1: Imaging Methodology
    1. Advances in PET Methodology
    Vesna Sossi
    2. Advances in MRI Methodology
    Tayyabah Yousaf, George Dervenoulas and Marios Politis
    3. Advances in SPECT Methodology
    Alberto Cuocolo, Sabina Pappatà, Emilia Zampella and Roberta Assante
    4. Hybrid PET/MRI Methodology
    Marco Aiello, Carlo Cavaliere, Rocco Marchitelli, Antonio d'Albore, Enrico De Vita and Marco Salvatore

    Section 2: Imaging Applications in Parkinson's Disease
    5. Molecular Imaging of the Dopaminergic System in Idiopathic Parkinson’s Disease
    Edoardo R. de Natale, Flavia Niccolini, Heather Wilson and Marios Politis
    6. Molecular Imaging of the Serotonergic System in Parkinson’s Disease
    Gennaro Pagano and Marios Politis
    7. Molecular Imaging of the Cholinergic System in Parkinson’s Disease
    Nicolaas I. Bohnen, Prabesh Kanel and Martijn L.T.M. Müller
    8. Molecular Imaging of the Noradrenergic System in Idiopathic Parkinson's Disease
    Adjmal Nahimi, Martin B. Kinnerup, Michael Sommerauer, Albert Gjedde and Per Borghammer
    9. Molecular Imaging of Opioid System in Idiopathic Parkinson’s Disease
    S. Thobois, C. Brefel-Courbon, D. Le Bars and V. Sgambato
    10. Molecular Imaging of the Cannabinoid System in Idiopathic Parkinson’s Disease
    Roberto Cilia
    11. Molecular Imaging of Neuroinflammation in Idiopathic Parkinson’s Disease
    Andreas-Antonios Roussakis and Paola Piccini
    12. Molecular Imaging of Addictive Behavior in Idiopathic Parkinson's Disease
    Christine Ghadery, Mikaeel Valli, Alexander Mihaescu, Rebecca Strafella, Irene Navalpotro, Jinhee Kim and Antonio P. Strafella
    13. Structural MRI in Idiopathic Parkinson’s Disease
    Rosa De Micco, Antonio Russo and Alessandro Tessitore
    14. Functional MRI in Idiopathic Parkinson's Disease
    Massimo Filippi, Sarasso Elisabetta, Noemi Piramide and Federica Agosta

Product details

  • No. of pages: 485
  • Language: English
  • Copyright: © Academic Press 2018
  • Published: October 9, 2018
  • Imprint: Academic Press
  • Hardcover ISBN: 9780128154182
  • eBook ISBN: 9780128154199

About the Serial Volume Editor

Marios Politis

Professor Marios Politis (MD MSc DIC PhD FRCP FEAN) is a Professor of Neurology, Consultant Neurologist, the Director of Neurodegeneration Imaging Group and the Director of Mireille Gillings Neuroimaging Centre at the University of Exeter. His research involves the use of Positron Emission Tomography (PET) and Single Photon Emission Tomography (SPECT) molecular imaging, structural and functional Magnetic Resonance Imaging (MRI), CSF and blood molecular markers, digital markers and clinical observation as methods of investigating aetiology, pathophysiology, and effects and complications of novel therapies in Neurodegenerative disorders. Professor Marios Politis has receive a high number of awards for clinical, research, and clinical research excellence including a research achievement award by the MRC (2010), the Movement Disorder Society Award for Outstanding and Innovative Clinical Research (2012), the IMPETus award for innovative and outstanding PET molecular imaging research (2013, 2014, 2015, 2016) and the PET Investigator Award from the Society of Nuclear Medicine and Molecular Imaging (2015). In 2016, he was elected Fellow of the European Academy of Neurology for outstanding contribution in neurodegenerative research. In 2017, he received the Jon Stolk Award in Movement Disorders from the American Academy of Neurology and was elected Fellow of Royal College of Physicians. Professor Marios Politis has significant industry experience by serving as a clinical investigator, consultant and principal investigator in several collaborations with industrial partners and pharma including a number of clinical trials. He has trained over 120 clinical and non-clinical fellows, research associates and research assistants, and undergraduate and postgraduate students at NIG. He has raised a record amount of over £60 million for cutting-edge research in neurodegenerative conditions such as Parkinson’s disease, Alzheimer’s disease and other neurodegenerative disorders; and is actively collaborating with a high number of philanthropic, government, non-commercial and commercial industrial partners. Professor Marios Politis has published over 150 high impact papers and has been running a specialist Neurology and Movement Disorder clinical service for over 15 years with previous appointments at UCLH, Hammersmith and Charring Cross Hospitals, and King’s College Hospital.

Affiliations and Expertise

Professor of Neurology, Consultant Neurologist, the Director of Neurodegeneration Imaging Group and the Director of Mireille Gillings Neuroimaging Centre at the University of Exeter, London, United Kingdom.

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