Image-Guided Neurosurgery provides readers with an update on the revolutionary improvements in imaging and visualization relating to neurosurgery. From the development of the pneumoencephalogram, to the operating microscope, to cross sectional imaging with CT and later MRI, to stereotaxy and neuronavigation, the ability to visualize the pathology and surrounding neural structures has been the driving factor leading surgical innovation and improved outcomes.

The book provides a comprehensive reference on the application of contemporary imaging technologies used in neurosurgery. Specific techniques discussed include brain biopsies, brain tumor resection, deep brain stimulation, and more.

The book is ideal for neurosurgeons, interventional radiologists, neurologists, psychiatrists, and radiologists, as well as technical experts in imaging, image analysis, computer science, and biomedical engineering.

Key Features

  • A comprehensive reference on image-guided neurosurgery
  • Includes coverage of neuronavigation in cranial surgery and advanced imaging, including functional imaging, adoption of intra-operative MRI and emerging technologies
  • Covers all image-guided neurosurgery tools, including robotic surgical devices
  • Ideal reference for topics relating to neurosurgery, imaging, stereotaxis, radiosurgery, radiology, epilepsy, MRI, the use of medical robotics, lasers, and more


Neurosurgeons, neurologists, psychiatrists, and radiologists, as well as technical experts in imaging, image analysis, computer science, and biomedical engineering

Table of Contents

  • Dedication
  • Foreword
  • List of Contributors
  • Chapter 1. Introduction and Historical Perspectives on Image-Guided Surgery
    • Stereotactic Frames
    • Advent of Volumetric Tomography
    • Image Guidance
    • Optical Localization
    • Registration
    • Beyond Points
    • Intraoperative Imaging
    • Deformation Correction
    • Work Underway
    • Dedication
    • References
  • Section I: Methods
    • Chapter 2. Background on Imaging Structural Imaging
      • Introduction
      • Basic Magnetic Resonance Imaging
      • CT/Dynamic CTA/CT Perfusion
      • Safety of CT and MRI
      • Conclusion
      • References
    • Chapter 3. Advanced Functional Imaging: fMRI, PET, and MEG
      • Introduction
      • Positron Emission Tomography
      • Functional Magnetic Resonance Imaging
      • Magnetoencephalography
      • Conclusion
      • References
    • Chapter 4. Imaging White Matter Anatomy for Brain Tumor Surgery
      • Introduction
      • Theoretical Foundations of Diffusion MRI
      • Diffusion MRI in Practice: Image Acquisition Artifacts
      • Diffusion Tensor Imaging
      • High Angular Resolution Diffusion Imaging
      • Diffusion MRI Tractography
      • Conclusion
      • References
    • Chapter 5. Background on Stereotaxis
      • Introduction
      • Laboratory Work
      • First Human Stereotaxis
      • Development of Computational Stereotaxy and Image Guidance
      • References
    • Chapter 6. Role of Computers and Image Processing in Image-Guided Brain Tumor Surgery
      • Introduction
      • Segmentation
      • Tractography
      • Registration
      • Navigation
      • Conclusion
      • References
    • Chapter 7. Intraoperative Imaging
      • Introduction: Intraoperative Imaging Modalities
      • Navigation and Imaging
      • Intraoperat


No. of pages:
© 2015
Academic Press
eBook ISBN:
Print ISBN:

About the editor

Alexandra Golby

Affiliations and Expertise

Associate Professor of Neurosurgery and Radiology, Harvard Medical School; Associate Surgeon, Director of Image-guided Neurosurgery, Clinical Co-Director AMIGO; Co-Director Clinical Functional MRI, Brigham and Women's Hospital, Department of Neurosurgery, Boston, MA, USA