Identification of Neural Markers Accompanying Memory

Identification of Neural Markers Accompanying Memory

1st Edition - November 23, 2013

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  • Author: Alfredo Meneses
  • Paperback ISBN: 9780124081390
  • eBook ISBN: 9780124167117

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Identification of Neural Markers Accompanying Memory is a fresh and novel volume of memory study, providing up-to-date and comprehensive information for both students and researchers focused on the identification of neural markers accompanying memory. Contributions by experts in specific areas of memory study provide background on and definitions of memory, memory alterations, and the brain areas involved in memory and its related processes, such as consolidation, retrieval, forgetting, amnesia, and antiamnesiac effects. With coverage of the principal neurotransmitters related to memory, brain disorders presenting memory alterations, and available treatments—and with discussion of neural markers as new targets for the treatment of memory alterations—Identification of Neural Markers Accompanying Memory is a necessary and timely work for researchers in this growing field.

Key Features

  • Discusses the alterations of memory in diverse diseases
  • Includes coverage from a basic introduction of memory investigation
  • Reviews brain areas and neurotransmitters involved in memory
  • Discusses behavioral models of memory
  • Contains novel insights into the complexity of signaling and memory
  • Includes the neuropharmacological and neurobiological bases of memory


Students, academics, and industry researchers working in the area of memory investigation

Table of Contents

  • Dedication

    List of Contributors

    1. Introduction

    Neurotransmitters and Memory: Introduction


    2. Neurotransmitters and Memory: Cholinergic, Glutamatergic, GaBAergic, Dopaminergic, Serotonergic, Signaling, and Memory

    Neurotransmitters and Memory

    5-HT Systems and Neurobiological Markers Related to Memory Systems

    5-HT Neural Markers and Memory

    Brain Areas, Biochemical Pathways, Cognitive-Enhancing Effects of 5-HT Receptor Drugs

    5-HT Pathways, Receptors, and Transporter: Memory Functions and Dysfunctions

    Protocols of Training/Testing, Memory Tasks, and Drugs

    Loci, Mechanisms of Action, and Memory Tasks

    Memory Tasks and Signaling

    Brain Areas, Neurotransmitters Systems, Drugs: Cognitive and Behavioral Demand of Memory Tasks and Protocols of Training: a Final Consideration

    Signaling and Memory



    3. The Role of GABA in Memory Processes


    GABA Receptors

    GABA and Its Correlation with Memory


    4. Involvement of Glutamate in Learning and Memory


    Glutamate Receptors

    Glutamate, Memory, and HF



    5. Dopamine and Memory

    Pharmacology of Dopamine

    Anatomy of the Dopaminergic System

    Basal Ganglia

    Working Memory

    Reinforcement Learning

    Dopamine and Neural Plasticity

    Dopamine and Memory Consolidation



    6. Unpacking Memory Processes: Using the Attribute Model to Design Optimal Memory Tests for Rodent Models


    Attribute Model

    Applying the Attribute Model



    7. Protein Synthesis and Memory: A Word of Caution



    8. Basic Elements of Signal Transduction Pathways Involved in Chemical Neurotransmission


    Some Central Concepts on Cell-to-Cell Communication

    G-Protein-Coupled Receptors

    GPCR Activation


    Receptor Desensitization

    β-Arrestin-Dependent Signaling

    Small GTPases

    The Second Messengers

    Cyclic Adenosine Monophosphate

    Inositol 1,4,5 Triphosphate


    Mitogen-Activated Protein Kinases

    The Transcription Factors

    Epigenetic Modifications


    9. A Role for Learning and Memory in the Expression of an Innate Behavior: The Case of Copulatory Behavior


    Male Rat Sexual Behavior

    Effects of Sexual Experience on Copulatory Behavior Expression

    Effects of Sexual Experience on Brain Functioning

    Brain Regions Involved in Sexual Experience-Induced Behavioral Changes



    10. Memory Disorders: The Diabetes Case


    Glucose Regulation, Diabetes, and AD

    Insulin, IR, and AD

    Apolipoprotein E and AD

    Cholesterol and AD

    Caffeine and AD



Product details

  • No. of pages: 180
  • Language: English
  • Copyright: © Elsevier 2013
  • Published: November 23, 2013
  • Imprint: Elsevier
  • Paperback ISBN: 9780124081390
  • eBook ISBN: 9780124167117

About the Author

Alfredo Meneses

Affiliations and Expertise

Department of Pharmacobiology, CINVESTAV (Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional), Mexico

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