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Introduction. The Structure of the Skin.
General. The epidermis. The dermis. The skin appendages.
Radiation Effects on the Skin.
Terminology used to identify the responses of skin to radiation. Late erythema, dermal ischaemia and necrosis. Radiation-induced skin reactions specific to radiological protection. Dose-effect relationships and threshold doses. Experimental studies on the effects of irradiation with 'hot particles'.
Experimental Radiation Carcinogenesis.
Types of radiation-induced tumours in experimental animals. Mechanisms of radiation-induced skin cancer.
Radiation-Induced Skin Cancer in Humans.
Variations in susceptibility to non-melanotic skin cancer. Immunosuppression and skin cancer. Studies of skin cancer in irradiated populations. Interaction of ionising and UV radiation in skin cancer induction.
Dose Limits and the Factors Influencing Risk Estimates.
Stochastic effects. Deterministic effects. General dosimetric considerations related to skin dose limitation.
Glossary. Acknowledgements. References.
- © 1992
- 29th April 1992
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