Hyperkinetic Movement Disorders

Hyperkinetic Movement Disorders

1st Edition - May 23, 2011

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  • Editors: William Weiner, Eduardo Tolosa
  • Hardcover ISBN: 9780444520142
  • eBook ISBN: 9780444534873

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The Handbook of Clinical Neurology Vol 100: Hyperkinetic Movement Disorders discusses hyperkinetic disorders related mainly to basal ganglia dysfunction and pathology. It contains 13 sections and 51 chapters written by authoritative and experienced investigators and clinicians in this extremely broad and diverse group of diseases and syndromes. The first section on choreoathetoid diseases and syndromes includes chapters on Huntington’s disease and Huntington’s disease look-alikes; spinocerebellar degenerations; neuroacanthocytosis; entatorubral-pallidoluysian atrophy; neuroferritinopathy; neurodegeneration with brain iron accumulation; mitochondrial disorders; acquired hepatocerebral degeneration; benign hereditary chorea; and “senile chorea.” The remaining chapters focus on the abnormal involuntary movements associated with each disease or syndrome. These include immune-related chorea, vascular chorea, metabolic disturbances that can induce chorea, chorea in other medical settings (e.g., postpump chorea in children, cancer-related paraneoplastic syndromes), myoclonus, essential tremor, and dystonia, including dystonia plus syndromes. There are also chapters on tardive dyskinesia, unusual clinical syndromes, and tics and stereotyped movements in children. The text is a valuable resource for neurology and psychiatry residents, practicing neurologists and psychiatrists, and specialists in movement disorders.

Key Features

  • An authoritative, comprehensive guide to movement disorders
  • An invaluable reference for the diagnosis and treatment of hyperkinetic diseases and syndromes
  • High-level discussions that are ideal for specialists in movement disorders, practitioners and residents alike


Neurologists, Neuroscience research workers

Table of Contents

  • Foreword




    Section 1 Choreoathetoid diseases and syndromes

    1. Huntington’s disease – clinical signs, symptoms, presymptomatic diagnosis, and diagnosis

    2. Huntington’s disease

    3. Molecular biology of Huntington’s disease

    4. Huntington’s disease – neuropathology

    5. Huntington’s disease look-alikes

    6. Spinocerebellar degenerations

    7. Neuroacanthocytosis

    8. Dentatorubral pallidoluysian atrophy

    9. Neurodegeneration with brain iron accumulation

    10. Movement disorders and mitochondrial disease

    11. Acquired hepatocerebral degeneration

    12. Benign hereditary chorea

    13. Senile chorea

    Section 2 Immune-related chorea

    14. Sydenham’s chorea

    15. Chorea gravidarum

    16. Antiphospholipid syndrome and other lupus-related movement disorders

    Section 3 Vascular-related chorea

    17. Hemiballismus

    18. Vascular chorea in adults and children

    19. Polycythemia and chorea

    Section 4 Metabolic disturbances

    20. Hyperthyroid chorea

    21. Hyperglycemic nonketotic states and other metabolic imbalances

    Section 5 Chorea in other medical settings

    22. Postoperative encephalopathy with choreoathetosis

    23. Movement disorders in patients with multiple sclerosis

    24. Paraneoplastic syndromes causing movement disorders

    25. Hyperkinetic movement disorders associated with HIV and other viral infections

    26. Chorea caused by toxins

    27. Drug-induced hyperkinetic movement disorders by nonneuroleptic agents

    Section 6 Other syndromes

    28. Paroxysmal choreodystonic disorders

    29. Painful legs and moving toes

    Section 7 Athetosis

    30. Birth-related syndromes of athetosis and kernicterus

    Section 8 Myoclonus

    31. Myoclonus

    32. Startle syndromes

    Section 9 Essential tremor

    33. Essential tremor

    34. Management of essential tremor, including medical and surgical approaches

    35. Orthostatic tremor – a review

    Section 10 Dystonia

    36. Early-onset primary dystonia

    37. Adult-onset dystonia

    38. Nonprimary dystonias

    39. Dopa-responsive dystonia

    40. Rapid-onset dystonia-parkinsonism

    41. Myoclonus-dystonia syndrome

    Section 11 Tardive dyskinesia

    42. Typical and atypical neuroleptics

    43. Epidemiology of tardive dyskinesia before and during the era of modern antipsychotic drugs

    44. Unusual focal dyskinesias

    Section 12 Tics

    45. Stereotypic movement disorders

    46. Tourette syndrome and other tic disorders

    Section 13 Other syndromes

    47. Restless legs syndrome

    48. Hemifacial spasm

    49. Wilson’s disease

    50. Task-specific tremor

    51. Hyperkinetic psychogenic movement disorders


Product details

  • No. of pages: 768
  • Language: English
  • Copyright: © Elsevier 2011
  • Published: May 23, 2011
  • Imprint: Elsevier
  • Hardcover ISBN: 9780444520142
  • eBook ISBN: 9780444534873

About the Editors

William Weiner

Affiliations and Expertise

Professor and Chairman, Department of Neurology, University of Maryland School of Medicine; Director, Maryland Parkinson's Diseases and Movement Disorders Centre, Baltimore, MD, USA

Eduardo Tolosa

Affiliations and Expertise

Chief of Neurology Service, Hospital Clinic, University of Barcelona, Spain

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