Hyperkinetic Movement Disorders, Volume 100

1st Edition

Editors: William Weiner Eduardo Tolosa
Hardcover ISBN: 9780444520142
eBook ISBN: 9780444534873
Imprint: Elsevier
Published Date: 23rd May 2011
Page Count: 768
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Table of Contents

Foreword Preface Dedication Contributors Section 1 Choreoathetoid diseases and syndromes

1. Huntington’s disease – clinical signs, symptoms, presymptomatic diagnosis, and diagnosis 2. Huntington’s disease 3. Molecular biology of Huntington’s disease 4. Huntington’s disease – neuropathology 5. Huntington’s disease look-alikes 6. Spinocerebellar degenerations 7. Neuroacanthocytosis 8. Dentatorubral pallidoluysian atrophy 9. Neurodegeneration with brain iron accumulation 10. Movement disorders and mitochondrial disease 11. Acquired hepatocerebral degeneration 12. Benign hereditary chorea 13. Senile chorea

Section 2 Immune-related chorea

14. Sydenham’s chorea 15. Chorea gravidarum 16. Antiphospholipid syndrome and other lupus-related movement disorders

Section 3 Vascular-related chorea

17. Hemiballismus 18. Vascular chorea in adults and children 19. Polycythemia and chorea

Section 4 Metabolic disturbances

20. Hyperthyroid chorea 21. Hyperglycemic nonketotic states and other metabolic imbalances

Section 5 Chorea in other medical settings

22. Postoperative encephalopathy with choreoathetosis 23. Movement disorders in patients with multiple sclerosis 24. Paraneoplastic syndromes causing movement disorders 25. Hyperkinetic movement disorders associated with HIV and other viral infections 26. Chorea caused by toxins 27. Drug-induced hyperkinetic movement disorders by nonneuroleptic agents

Section 6 Other syndromes

28. Paroxysmal choreodystonic disorders 29. Painful legs and moving toes

Section 7 Athetosis

30. Birth-related syndromes of athetosis and kernicterus

Section 8 Myoclonus

31. Myoclonus 32. Startle syndromes

Section 9 Essential tremor

33. Essential tremor 34. Management of essential tremor, including medical and surgical approaches 35. Orthos


The Handbook of Clinical Neurology Vol 100: Hyperkinetic Movement Disorders discusses hyperkinetic disorders related mainly to basal ganglia dysfunction and pathology. It contains 13 sections and 51 chapters written by authoritative and experienced investigators and clinicians in this extremely broad and diverse group of diseases and syndromes.

The first section on choreoathetoid diseases and syndromes includes chapters on Huntington’s disease and Huntington’s disease look-alikes; spinocerebellar degenerations; neuroacanthocytosis; entatorubral-pallidoluysian atrophy; neuroferritinopathy; neurodegeneration with brain iron accumulation; mitochondrial disorders; acquired hepatocerebral degeneration; benign hereditary chorea; and “senile chorea.” The remaining chapters focus on the abnormal involuntary movements associated with each disease or syndrome. These include immune-related chorea, vascular chorea, metabolic disturbances that can induce chorea, chorea in other medical settings (e.g., postpump chorea in children, cancer-related paraneoplastic syndromes), myoclonus, essential tremor, and dystonia, including dystonia plus syndromes. There are also chapters on tardive dyskinesia, unusual clinical syndromes, and tics and stereotyped movements in children.

The text is a valuable resource for neurology and psychiatry residents, practicing neurologists and psychiatrists, and specialists in movement disorders.

Key Features

  • An authoritative, comprehensive guide to movement disorders
  • An invaluable reference for the diagnosis and treatment of hyperkinetic diseases and syndromes
  • High-level discussions that are ideal for specialists in movement disorders, practitioners and residents alike


Neurologists, Neuroscience research workers


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© Elsevier 2011
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Hardcover ISBN:

About the Editors

William Weiner Editor

Affiliations and Expertise

Professor and Chairman, Department of Neurology, University of Maryland School of Medicine; Director, Maryland Parkinson's Diseases and Movement Disorders Centre, Baltimore, MD, USA

Eduardo Tolosa Editor

Affiliations and Expertise

Chief of Neurology Service, Hospital Clinic, University of Barcelona, Spain