Human Pathogenic Microbes

Diseases and Concerns

1st Edition - March 16, 2022
Author: Manzoor Ahmad Mir
Language: English
Paperback ISBN:
9 7 8 - 0 - 3 2 3 - 9 6 1 2 7 - 1
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 5 4 2 6 - 6

Considering the global emerging human pathogenic microbial diseases and trends, Human Pathogenic Microbes is framed to provide deep insights into the epidemic and emerging… Read more

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Considering the global emerging human pathogenic microbial diseases and trends, Human Pathogenic Microbes is framed to provide deep insights into the epidemic and emerging bacterial and fungal infections and diseases in humans. It presents novel, up-to-date, and cutting-edge knowledge regarding various human pathogenic microbes, their associated drug resistance mechanisms, and different diseases caused by them.

Human Pathogenic Microbes reflects the current research and development on the evolution of bacterial and fungal drug resistance: different bacterial and fungal antimicrobial drug resistance mechanisms along with their biological and molecular aspects.

In a nutshell, Human Pathogenic Microbes describes a various bacterial and fungal diseases caused by different human pathogenic microbes employing different drug resistance mechanisms and processes. It also highlights the novel emerging approaches (Immunological and combinatorial) that will aid to fight against such bacterial and fungal pathogens.

Cover image
Title page
Table of Contents
Copyright
List of contributors
Preface
Acknowledgments
Abbreviation list
Glossary
Chapter 1. Human pathogenic microbes (bacterial and fungal) and associated diseases
1.1. Introduction
1.2. Human–pathogen interaction
1.3. Human pathogenic fungal microorganisms
1.4. Human pathogenic fungal diseases
1.5. Human pathogenic bacterial microorganisms
1.6. Human pathogenic bacterial diseases
1.7. Summary and future perspectives
Chapter 2. Evolution of antimicrobial drug resistance in human pathogenic bacteria
2.1. Introduction
2.2. Current status of resistance to antibacterial drugs
2.3. Surveillance of antibacterial resistance/tolerance
2.4. Molecular mechanisms of antimicrobial drug resistance in human pathogenic bacteria
2.5. Resistance to antibacterial drugs in selected bacteria of international concern
2.6. Economic burden of antibacterial resistance and its impacts on human health
2.7. Surveillance of antimicrobial drug resistance in disease-specific programs
2.8. Evolution of drug resistance in mycobacterium tuberclosis
2.9. Future perspectives
Chapter 3. Evolution of antimicrobial drug resistance in human pathogenic fungi
3.1. Introduction
3.2. Molecular mechanisms governing antimicrobial drug resistance phenomenon in the human pathogenic fungi
3.3. Conclusions
Chapter 4. Combating human bacterial infections: need for new antibacterial drugs and therapeutics
4.1. Introduction
4.2. Common human bacterial infections
4.3. Salmonellosis
4.4. Tuberculosis
4.5. Cholera
4.6. Development of new antimicrobial agents
4.7. Future perspectives
Chapter 5. Combating human fungal infections: need for new antifungal drugs and therapies
5.1. Introduction
5.2. Different classes of antifungals
5.3. Need for new antifungal drugs and therapies
5.4. Potential alternative antifungals to combat drug resistance in pathogenic fungi
5.5. Future perspectives
Chapter 6. Significance of immunotherapy for human bacterial diseases and antibacterial drug discovery
6.1. Introduction
6.2. Immunotherapy and its types
6.3. Immunotherapies for bacterial infections
6.4. Emerging technologies against bacterial pathogens
6.5. Adjuvant immunotherapies as novel strategies to bacterial infection
6.6. Development of therapeutic antibodies
6.7. Future perspectives
Chapter 7. Significance of immunotherapy for human fungal diseases and antifungal drug discovery
7.1. Introduction
7.2. Human fungal infections
7.3. Potential immunotherapies for fungal diseases
7.4. Different immunotherapeutic approaches against human fungal infections
7.5. Advantages of immunotherapies for fungal diseases
7.6. Future perspectives
Chapter 8. Combinatorial approach to combat drug resistance in human pathogenic bacteria
8.1. Introduction
8.2. Food-borne bacterial infections
8.3. Antibiotic treatment and their efficiency analysis
8.4. Antibiotic resistance and antimicrobial resistance shown by Salmonella
8.5. Future approach to fight salmonellosis
8.6. Combinatorial approach in tuberculosis
8.7. Therapeutics and their efficiency analysis
8.8. Advanced therapeutics for tuberculosis
8.9. Current therapeutics for treatment of cholera
8.10. Advanced therapies against human pathogenic bacteria
8.11. Future perspectives
Chapter 9. Combinatorial approach to combat drug resistance in human pathogenic fungi
9.1. Introduction
9.2. Major classes of antifungal drugs
9.3. Overview of combination therapy
9.4. Mechanism of drug interactions
9.5. Benefits of using drug combinations/applications of combinatorial approach
9.6. Future perspectives
Chapter 10. Recent trends in the development of bacterial and fungal vaccines
10.1. Introduction
10.2. Understanding host–pathogen interaction
10.3. Immunity and vaccination
10.4. Vaccine development against bacterial pathogens
10.5. Understanding vaccine development against fungal pathogens
10.6. Future perspectives
Index

Manzoor Ahmad Mir

Dr. Manzoor Ahmad Mir holds Master’s Degree in Zoology from HNBG Central University and after qualifying prestigious National level CSIR-JRF-NET examination he worked jointly for his Ph. D at Jawaharlal Nehru University New Delhi and CSIR-Institute of Microbial Technology Chandigarh in the field of Immunology. His basic research interests include Cancer Biology, Combination therapy in Breast Cancer, molecular immunology and Tuberculosis immunology. He has published more than 50 high-impact research papers and book chapters, in recognition of which he has received several awards and Royalties from international publishing houses. Dr. Manzoor has authored more than 15 books with international publishers like Elsevier USA and Nova Science Publisher USA, Bentham Sciences, IGI Global, Springer-Nature. He is on the editorial board and Reviewer of some prestigious journals like DOVE medical press, Springer Plus, Cancer Biomarkers, Frontiers, Plos etc and has been an invited speaker at various scientific meetings/conferences within India and abroad. He is member of many scientific organizations and societies like American Association of Cancer Research, Fellow of Royal British Society, International Immunology Association, Indian Cancer Society, Indian Immunology Society, Indian National Science Association, IMMUNOCON etc. Dr Manzoor was awarded Teachers Associate Research Excellence Fellowship (TARE) by DST Govt of India. He has been awarded Summer Research Fellowship Programme (SRFP-2019) by Indian Academy of Sciences and National Science Academy. He was awarded a research project on combination therapy in breast cancer by J&K Science Technology and Innovation. Dr Manzoor has developed Massive Open Online Course (MOOCs) in Immunology course and Endocrinology course for UG students sanctioned by UGC-Consortium for Educational Communication (CEC) SWAYAM Ministry of HRD Govt of India. He has research and teaching experience of 15 years. He currently teaches Cancer Biology, and Immunology at the Department of Bioresources, School of Biological Sciences, University of Kashmir. He is presently heading the Department of Bioresources, University of Kashmir.

Affiliations and expertise

Department of Bioresources, School of Biological Sciences, University of Kashmir, Srinagar, India