Description

This textbook provides a thorough and comprehensive overview of the human brain and spinal cord for medical and graduate students as well as residents in the clinical neurosciences. Standing on the shoulders of training from outstanding scientist-teacher mentors and based on more than 30 years of experience teaching about the brain and spinal cord to medical and graduate students, this single authored text presents everything the reader would need as they begin their study of the nervous system. At the same time the experienced neuroscientist will find much useful and valuable information in these pages that is based almost exclusively on studies in experimental primates and observations in humans. Every effort has been made to present the complexities of the nervous system as simply and clearly as possible. The careful reader will discover a clarity and depth of coverage that makes the reading both instructional and enjoyable. Topics are presented logically and the text in an easy-to-read style. The accompanying line drawings emphasize important concepts in a clear and uncluttered manner. Topics presented: Neurons, glial cells, degeneration, regeneration, axonal transport Review of the development of the human nervous system Overview of the anatomy of the spinal cord, brain stem and forebrain General sensory paths (pain, temperature, touch, pressure, proprioception) Special sensory systems (auditory, vestibular, visual, olfactory and gustatory) Eye movements and visual reflexes Comprehensive presentation of the regions involved in motor activity including the clinical manifestation of injuries to these motor areas Limbic system, hypothalamus and the autonomic nervous system Lobes of the brain, clinically important cortical areas and the results of lesions in these areas Blood

Key Features

* Presents the complexities of the nervous system as simply and clearly as possible * Written with a clarity and depth of coverage that makes the reading both instructional and enjoyable * Includes numerous illustrations emphasizing important concepts

Readership

Medical and graduate students, neuroscientists, and neurologists.

Table of Contents

Contents Preface Chapter 1: Introduction to the Nervous System 1.1. Neurons 1.1.1. Neuronal Cell Body (Soma) 1.1.2. Axon Hillock 1.1.3. Neuronal Processes – Axons and Dendrites 1.2. Classification of Neurons 1.2.1. Neuronal Classification by Function 1.2.2. Neuronal Classification by Number of Processes 1.3. The Synapse 1.3.1. Components of a Synapse 1.3.2. Neurotransmitters and Neuromodulators 1.3.3. Neuronal Plasticity 1.3.4. The Neuropil 1.4. Neuroglial Cells 1.4.1. Neuroglial Cells differ from Neurons 1.4.2. Identification of Neuroglia 1.4.3. Neuroglial Function 1.4.4. Neuroglial Cells and Aging 1.5. Axonal Transport 1.5.1. Functions of Axonal Transport 1.5.2. Defective Axonal Transport 1.6. Degeneration and Regeneration 1.6.1. Axon or Retrograde Reaction 1.6.2. Anterograde Degeneration 1.6.3. Retrograde Degeneration 1.6.4. Regeneration of Peripheral Nerves 1.6.5. Regeneration and Neurotrophic Factors 1.6.6. Regeneration in the Central Nervous System 1.7. Neural Transplantation Further Reading Chapter 2: Development of the Nervous System 2.1. First Week of Development (Fertilization, Free Blastocyst, Attaching Blastocyst) 2.1.1. Fertilization 2.1.2. From Two Cells to the Free Blastocyst 2.2. Second Week of Development (Implantation, Primitive Streak Appears, Three Layers of Cells) 2.2.1. Implantation and the Appearance of Two Distinct Layers of Cells 2.2.2. Primitive Streak and a Third Layer of Cells Appear 2.3. Third Week of Development (Neural Plate, Groove, and Folds, Three Main Divisions of the Brain) 2.3.1. Primitive Node and Notochordal Process Appear 2.3.2.

Details

No. of pages:
512
Language:
English
Copyright:
© 2008
Published:
Imprint:
Academic Press
Print ISBN:
9780120682515
Electronic ISBN:
9780080554181

About the author

James R. Augustine

Affiliations and Expertise

University of South Carolina, School of Medicine, Columbia, SC, USA

Reviews

"The book is well done, well written and beautifully illustrated. I have looked at every page, and admired the many illustrations. The precision of the neuroanatomical details should be a wake-up call to all the "generalities" fostered by those who tout "Neuroscience." I hope the book does well!" --Isabel Lockard, Ph.D., Professor Emeritus, Cell Biology and Anatomy, the Medical University of South Carolina, Charleston, USA