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Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases discusses neurodegenerative diseases and their epidemiology and clinical presentation, describes the structural organization of human caspases, their classification, role with mitochondria, and mechanisms of activation, including extensive discussions of neuronal apoptosis and its pathways and underlying mechanisms. Finally, the book discusses the intricate mechanisms and interplay between human caspases and neuronal apoptosis in neurodegenerative diseases. All of this is undercut with extensive coverage of molecular events in the pathogenesis of neurodegenerative disorders. Biomedical researchers, graduate students and scientists, along with neuroscientist and student trainees will greatly benefit from this comprehensive information.
Neurodegenerative diseases are characterized by progressive structural and/or functional deterioration and eventual death of affected neurons. The progression of these disorders shares similarities at the molecular level. The programmed cell death manifests as blebbing of the plasma membrane, protein degradation, DNA damage and clearance of dead cells by scavengers.
- Describes the various intricate mechanisms and interplay between human caspases and neuronal apoptosis in neurodegenerative diseases
- Provides a detailed description of the structural organization and mechanisms of action of various caspases in regulating the process of apoptosis in neurodegenerative diseases
- Explores the role of various caspases in cell death
Biomedical researchers, graduate students, and scientists, as well as neuroscientist and student trainees
- Neurodegenerative Diseases: Neuropathology, Genetics and Epidemiology
- Role of Caspases, Apoptosis and Additional Factors in Pathology of Alzheimer’s disease
- Role of Caspases and Apoptosis in Parkinson’s disease
- Illustrated Etiopathogenesis of Huntington’s Disease
- No. of pages:
- © Academic Press 2021
- 1st December 2021
- Academic Press
- Paperback ISBN:
Prof. (Dr.) Anil Gupta, (DSc), PhD, MSc., BSc, BDS (Gold medalist), serves as the Vice-Principal, Medical Superintendent, Professor, and Head of the Department of Physiology and Biochemistry at Eklavya Dental College and Hospital, Rajasthan, India. He formerly served as Dean of Research, Professor, and Head of the Department of Physiology and Biochemistry at the Desh Bhagat University, Punjab, India. Additionally, he served as PhD guide in universities, resource person to PhD scholars, and PhD examiner. Prof. (Dr.) Anil Gupta has 25 years of clinical experience, 15 years of teaching experience, is a merit scholarship and merit certificate holder, and has authored 6 books. He has also attended and presented research papers at many conferences.
Department of Physiology and Biochemistry, Eklavya Dental College and Hospital, Rajasthan, India
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