Modern Trends in Physiological Sciences, Volume 32: Human Afflictions and Chromosomal Aberrations presents the study of the links between chromosome aberrations and physical and mental congenital anomalies. This book discusses the possibilities of human cytogenetic research as well as its difficulties. Organized into 15 chapters, this volume begins with an overview of the development of human chromosome investigations. This text then explains the methods for studying human chromosomes, which can be applied without controlling the atmosphere of the incubator. Other chapters describe the structural features of the normal human karyotype. This book discusses as well the early appearance of a chromosome aberration that produces a change in the hereditary patrimony manifest in a constitutional disorder of the individual. The final chapter deals with the biochemical effects that correspond to numerical or structural anomalies in chromosome 21. This book is a valuable resource for genetecists, cytogeneticists, physicians, and clinical researchers.
Preface To English Edition Preface Acknowledgments Introduction Chapter 1. History Chapter 2. Techniques of Studying Human Chromosomes Chapter 3. Normal Human Karyotype Chapter 4. Trisomy 21 Chapter 5. Numerical Autosomal Aberrations. Trisomies 13 and 18 Chapter 6. Other Autosomal Anomalies due to Excess or Deficiencies Chapter 7. Structural Rearrangements Chapter 8. Leukemias and Cancers Chapter 9. Numerical Gonosomal Aberrations. Ovarian Dysgenesis Chapter 10. Numerical Gonosomal Aberrations. Testicular Dysgenesis Chapter 11. Modifications of Gonosomal Structure Chapter 12. Hermaphroditism and Pseudo-hermaphroditism Chapter 13. Monozygotic Twinning and Chromosome Aberrations (Heterokaryotic Monozygotism) Chapter 14. Mechanism and Effects of Numerical Gonosomal Aberrations Chapter 15. Chromosome-linked Biochemical Effects References Index
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- © Pergamon 1969
- 1st January 1969
- eBook ISBN: