Hot Spot Pollutants

Hot Spot Pollutants

Pharmaceuticals in the Environment

1st Edition - November 30, 2004

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  • Editors: Daniel Dietrich, Simon Webb, Thomas Petry
  • eBook ISBN: 9780080521947

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Hot Spot Pollutants describes how pharmaceuticals and/or endocrine active compounds gain entry into the aquatic ecosystem, effects on specific organisms and the potential risk involved for the whole ecosystem. In addition it presents the latest views and developments regarding legal requirements for assessing the environmental risk of pharmaceuticals. This books includes the views of academic, industry and government scientists, and thus aims for a balanced presentation of all standpoints. The book consists of papers that appeared previously in the journal Toxicology Letters in 2002 and 2003, and have been collected in this single volume to make them accessible to a broader audience. Authors were asked to update their contributions where necessary. See also Toxicology Letters volume 131, issues 1 and 2 (2002), and volume 142 issue 3 (2003).

Key Features

* State-of-the-art information of pharmaceuticals in the environment
* Leading Academic, industry and government contributors
* Provides the views of the experts in the field
* Offers a thorough basis to attain a good overview including all facets of the field


Scientists in academia, pharmaceutical/chemical industries, and government involved in assessing the environmental risk of pharmaceuticals.

Table of Contents

  • Editorial
    Occurance, fate and removal of pharmaceutical residues in the aquatic environment: An extended review of recent research data
    The sorption and transport of a sulfonamide antibiotic in soil systems
    Concentrations of the UV filter ethylhexyl methoxycinnamate in the aquatic compartment: a comparision of modelled concentrations for Swiss surface waters with empirical monitoring data
    Exposure simulation for pharmaceuticals in European surface waters with GREAT-ER
    Indirect human exposure to pharmaceuticals via drinking water
    Morphological sex reversal upon short-term exposure to endocrine modulators in juvenile fathead minnow
    Determination of vitellogenin kinetics in male fathead minnows
    Integrated in vivo and in vitro assessment of reproductive and developmental effects of endocrine disrupters in invertebrates
    How can toxic effects of pollution of the aquatic environment on the immunocompetence of fishes be detected? A discussion on the relevance of biomarkers philosophy
    Aquatic ecotoxicology of fluoxetine: a review of recent research
    Aquatic ecotoxicity of pharmaceuticals: including the assessment of combination effects
    Environmental risk assessment of pharmaceutical drug substances – conceptual considerations
    Pharmacodynamic activity of drugs and ecotoxicology – can the two be connected?
    Proposed development of sediment quality guidelines under the European Water Framework Directive: A critique
    Prioritisation of veterinary medicines in the UK environment
    European medicines and feed additives regulation are not in compliance with environmental legislation and policy
    Environmental risk assessment of veterinary pharmaceuticals in the EU: Reply to Montforts and de Knecht
    Environmental risk assessment for new human pharmaceuticals in the European Union according to the 2003 draft guideline

Product details

  • No. of pages: 352
  • Language: English
  • Copyright: © Academic Press 2004
  • Published: November 30, 2004
  • Imprint: Academic Press
  • eBook ISBN: 9780080521947

About the Serial Volume Editors

Daniel Dietrich

Affiliations and Expertise

Environmental Toxicology, University of Konstanz, Germany

Simon Webb

Affiliations and Expertise

CEFIC, Brussels, Belgium

Thomas Petry

Affiliations and Expertise

The Weinberg Group LLC, Brussels, Belgium

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