Description

Hormones and Signaling focuses on the mechanism of gene regulation at the cellular level. It also covers the way hormones act to modulate gene regulation and animal development.

Key Features

@introbul:Key Features @bul:* Includes information on: @subul:* Nuclear receptors, coactivators, and corepressors * Membrane receptors, kinases, and phosphorylation on cascades * Hormonal regulation of development * Calcium channels and neurotransmitters * Chromatin, transcription factors, and regulation of gene expression * JAK/STAT pathways * Hormone-regulated development and gene "knock-out"

Readership

Researchers and students in endocrinology, cell and molecular biology, biochemistry, and pharmacology.

Table of Contents

E.B. Thompson, Glucocorticoid and Oxysterol-induces Apoptosis of Lymphoid Cells. A.M. Schmidt, J-L. Wautier, D.M. Stern, and S.D. Yun, RAGE: A Receptor with a Taste for Multiple Ligands and Varied Pathophysiologic States. R.J. Lefkowitz and A.D. Macrae, The Function and Regulation of the G Protein-Coupled Receptor Kinases. G. Kuiper, S. Nilsson, and J-A. Gustafsson, Characteristics and Function of the Novel Estrogen Receptor beta. M.E. Lippman and C.Tang, EGF Family Receptors and Their Ligands in Human Cancer. D.L. Garbers and T.A. Quill, Fertilization: Common Molecular Signaling Pathways Across the Species. A. Minden and M. Karin, The JNK Family of MAP Kinases: Regulation and Function. P. Devchand and W. Wahli, PPAR alpha: Tempting Fate with Fat. S.R. Datta and M.E. Greenberg, Molecular Mechanisms of Neuronal Survival and Apoptosis. D.J. Mangelsdorf and P.J. Willy, Nuclear Orphan Receptors: The Search for Novel Ligands and Signaling Pathways.

Details

No. of pages:
364
Language:
English
Copyright:
© 1998
Published:
Imprint:
Academic Press
Electronic ISBN:
9780080534145
Print ISBN:
9780123124111
Print ISBN:
9780123992260

About the editors

Tony Hunter

Tony Hunter received his Ph.D. in 1969 from the University of Cambridge, England. He joined the Salk Institute in 1975 as an assistant professor and has been a professor since 1982. His current interests are the protein-tyrosine kinases of the Src and growth factor receptor families and the protein-tyrosine phosphatases that remove the phosphates added by protein-tyrosine kinases. He was elected as a Fellow of the Royal Society of London in 1987, a Fellow of the American Academy of Arts and Sciences in 1992, and as an Associate Member of the European Molecular Biology Organization in 1992.

Reviews

@qu:"The editors and contributors are all well-known leaders in their disciplines. I enjoyed reading this book and I am sure that I will use it often as a reference tool. Chapters are generally well-written, interesting, and comprehensive... I look forward to future volumes in the series... I recommend this book as a valuable reference tool for all interested in endocrine signaling pathways." @source:--TRENDS IN ENDOCRINOLOGY AND METABOLISM @qu:"...it fills a particular niche by providing a rapid update on specialized aspects of the challenging field of regulatory biology." @source:--CELL