Hormone/Behavior Relations of Clinical Importance

Hormone/Behavior Relations of Clinical Importance

Endocrine Systems Interacting with Brain and Behavior

1st Edition - July 20, 2009

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  • Editors: Robert Rubin, Donald Pfaff
  • eBook ISBN: 9780080958002
  • Hardcover ISBN: 9780123749260

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A single volume of 41 articles, Hormone/Behavior Relations of Clinical Importance is an authoritative selection of relevant chapters from the Hormones Brain and Behavior 2e MRW, the most comprehensive source of neuroendocrinological information assembled to date (AP July 2009). The study of hormones as they impact the brain and, subsequently, behavior is a central topic in neuroscience, endocrinology and psychiatry. This volume offers an overview of neuroendocrinological topics, approaching the subject from the perspective of hormone-brain function, hormone-behavior relations, sex differences, and the impact on various diseases/pathologies. Many basic human behavioral functions are subject to the influence of hormones - sexual orientation, the experience of pain, fertility, immunity - as are clinical conditions such as diabetes, substance abuse disorder, eating disorders, PTSD, TBI, pain, Alzheimer's, stress/anxiety, affective disorders, and more. There is considerable commercial clinical potential in the study of hormones - drug companies are currently developing a Cholecystokinin (hormonal peptide) booster to reduce appetite in those who suffer from sever obesity, and catamenial epilepsy (features seizure exacerbation in relation to the menstrual cycle) is resistant to treatment by standard antiepileptic medications, but may be hormonally controlled. These issues and more are covered, and there is simply no other current single-volume reference with such comprehensive coverage and depth.Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 150 figures (50 in color). A collection of articles reviewing our fundamental knowledge of neuroendocrinology, the book provides an essential, affordable reference for researchers, clinicians and graduate students in the area.

Key Features

  • Offering outstanding scholarship, each chapter is written by an expert in the topic area and approximately 25% of chapters are written by international contributors (7 countries represented)
  • Provides more fully vetted expert knowledge than any existing work with broad appeal for the US, UK and Europe, accurately crediting the contributions to research in those regions
  • Heavily illustrated with 150 figures, approximately 50 in color, presenting the material in the most visually useful form for the reader
  • Fully explores various clinical conditions associated with the hormones and the brain (PTSD, TBI, Stress & Anxiety, eating disorders, diabetes, addictive disorders, Alzheimer's, affective disorders)
  • Broad coverage of disorders makes the volume relevant to clinicians as well as researchers and basic scientists


Basic science researchers, academic clinicians and graduate students in neuroendocrinology, neuroscience and endocrinology

Table of Contents

    1. Genetic Transmission of Behavior and Its Neuroendocrine Correlates, Boris Hambsch
    2. Hypothalamic-Pituitary-Adrenal Cortical axis, Michael E. Rhodes
    3. Hypothalamic-Pituitary-Thyroid axis, Russell Joffe
    4. Hypothalamic-Pituitary-Gonadal Axis in Women, David R. Rubinow
    5. Hypothalamic-Pituitary-Gonadal Axis in Men, Ronald S. Swerdloff
    6. Sex Differences in Human Brain Structure and Function, Larry Cahill
    7. Sex Differences in CNS Neurotransmitter Influences on Behavior, Michael E. Rhodes
    8. Gonadal Hormones and Sexual Differentiation of Human Brain and Behavior, Melissa Hines
    9. Human Puberty: Physiology and Genetic Regulation, Beth A. Kaminski
    10. The Biology of Sexual Orientation and Gender Identity, Francisco Sanchez
    11. Sexual Orientation in Men and Women, Louis JG Gooren
    12. Sex Differences in Competitive Confrontation and Risk-taking, Margo Wilson
    13. Prolactin Actions in the Brain, David Grattan
    14. Growth Hormone and Insulin-Like Growth Factor-1: Effects on the Brain, Zvi Laron
    15. Neurosteroids: From Basic Research to Clinical Perspectives, Cheryl Frye
    16. Brain peptides: From Laboratory to Clinic, Thomas D. Geracioti, Jr.
    17. Melatonin Actions in the Brain, Alfred J. Lewy
    18. Neuroendocrine-Immune Interactions: Implications for Health and Behavior, Thaddeus Pace

    19. Diseases of Hypothalamic Origin, John Carmichael
    20. Stress and Anxiety Disorders, Elizabeth A. Young
    21. Mood Disorders, Bernard J. Carroll
    22. Premenstrual Dysphoric Disorder, Barbara L. Parry
    23. Post-Traumatic Stress Disorder, Rachel Yehuda
    24. Anorexia Nervosa and Bulimia Nervosa, Gilberto J. Paz-Filho
    25. Aging and Alzheimer’s Disease, Sonia Lupien
    26. Genetic Defects of Female Sexual Differentiation, Arianne B. Dessens
    27. Genetic Defects of Male Sexual Differentiation, Yuan-Shan Zhu
    28. Assisted Reproduction in Infertile Women, Liora Baor
    29. Transsexualism, Rebecca Allison
    30. Disorders of Salt and Fluid Balance, Thorsten Lenhard
    31. Diabetes Mellitus and Neurocognitive Dysfunction, Chistopher Ryan
    32. Alcohol Abuse: Endocrine Concomitants, Elizabeth S. Ginsburg
    33. Effect of Smoking on Hormones, Brain and Behavior, Tanuj Sidhartha
    34. Cocaine, Hormones and Behavior, Nancy K. Mello
    35. Short-Acting Opiates vs. Long-Acting Opioids, Mary Jeanne Kreek
    36. Pain: Sex/Gender Differences, Anne Z. Murphy
    37. Traumatic Brain Injury, Brent E. Masel
    38. Human Immunodeficiency Virus and AIDS, Yoko Miyasaki

Product details

  • No. of pages: 1182
  • Language: English
  • Copyright: © Academic Press 2009
  • Published: July 20, 2009
  • Imprint: Academic Press
  • eBook ISBN: 9780080958002
  • Hardcover ISBN: 9780123749260

About the Editors

Robert Rubin

Donald Pfaff

Donald W. Pfaff heads the Laboratory of Neurobiology and Behavior at The Rockefeller University. He received his scientific training at Harvard College and MIT. He is a Member of the U.S. National Academy of Sciences and a Fellow of the American Academy of Arts and Sciences. Pfaff's laboratory focuses on steroid hormones and brain function, genes influencing neuronal functions, and generalized CNS arousal. He is the author or coauthor of over 10 books and more than 900 research publications.

Affiliations and Expertise

Laboratory of Neurobiology and Behavior, Rockefeller University, New York, USA

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