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Hormonal Proteins and Peptides
1st Edition - August 28, 1973
Editor: Choh Hao Li
Language: English
eBook ISBN:9781483257969
9 7 8 - 1 - 4 8 3 2 - 5 7 9 6 - 9
Hormonal Proteins and Peptides, Volume I reviews extensively the knowledge on the biology and chemistry of the protein and peptide hormones. This book presents the structures of…Read more
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Hormonal Proteins and Peptides, Volume I reviews extensively the knowledge on the biology and chemistry of the protein and peptide hormones. This book presents the structures of the various protein and peptide hormones. Organized into five chapters, this volume begins with an overview of the chemistry of several hormonal glycoproteins. This text then presents the research on the purification and chemistry of thyroid-stimulating hormone (TSH). Other chapters consider the study of ovine interstitial cell-stimulating hormone, and concentrate to some extent on the very closely related bovine species. This book discusses as well some aspects of the biology of the pituitary interstitial cell-stimulating hormone or luteinizing hormone in mammalian species. The final chapter deals with the correlation of the primary structure with function for a better understanding of the mechanism of action of the hormone at a molecular level. This book is a valuable resource for biologists, biochemists, and research workers.
List of ContributorsPrefaceContents of Volume II1. The Chemistry of Glycoproteins Text References2. The Chemistry of Pituitary Thyrotropin I. Introduction II. Preparation of Bovine TSH III. Purification of Human TSH IV. The Subunits of Bovine TSH and Their Linear Amino Acid Sequences V. The Carbohydrate Portion of Bovine TSH VI. A Comparison of the Molecular Parameters of Bovine TSH Determined Directly and as Deduced from the Sequence VII. The Chemical and Biological Relationships Between TSH, LH, and HCG (Human Chorionic Gonadotropin) VIII. Comparative Studies—Human TSH IX. Problems and Possibilities References3. The Chemistry of the Interstitial Cell-Stimulating Hormone of Ovine Pituitary Origin I. Introduction II. Purification of Ovine ICSH III. Physical Properties of Ovine ICSH IV. Chemical Properties of Ovine ICSH V. The Subunit Nature of ICSH VI. Structural Studies on the ICSH Subunits VII. Comments on the Heterogeneity of ICSH VIII. Concluding Remarks References4. The Biology of Pituitary Interstitial Cell-Stimulating Hormone I. Introduction II. Gonadotropic Factors of the Pituitary Gland III. Biological Effects of ICSH in the Female IV. Role of ICSH in Pregnancy V. Formation and Maintenance of Corpus Luteum VI. Biological Effects of ICSH in the Male VII. Extragonadal Actions of ICSH VIII. Regulation of ICSH Secretion IX. Metabolism of ICSH X. Effects of ICSH on Gonadal Metabolism XI. Concluding Remarks References5. Chemistry of Human Chorionic Gonadotropin I. General II. Methods of Purification of HCG III. Physicochemical Properties IV. Chemical Composition V. Amino and Carboxy Terminal Analyses VI. Quaternary Structure of HCG VII. Investigation of the Carbohydrate Units in HCG VIII. Amino Acid Sequence of HCG IX. General Considerations References6. Chemistry and Biosynthesis of Thyroid Iodoproteins I. Introduction: Definitions and Classifications II. Chemistry of Thyroid Iodoproteins III. Biosynthesis of Thyroid Iodoproteins ReferencesAuthor IndexSubject Index
No. of pages: 284
Language: English
Edition: 1
Published: August 28, 1973
Imprint: Academic Press
eBook ISBN: 9781483257969
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