Hormonal Proteins and Peptides - 1st Edition - ISBN: 9780124472013, 9781483257969

Hormonal Proteins and Peptides

1st Edition

Editors: Choh Hao Li
eBook ISBN: 9781483257969
Imprint: Academic Press
Published Date: 28th August 1973
Page Count: 284
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Hormonal Proteins and Peptides, Volume I reviews extensively the knowledge on the biology and chemistry of the protein and peptide hormones. This book presents the structures of the various protein and peptide hormones.

Organized into five chapters, this volume begins with an overview of the chemistry of several hormonal glycoproteins. This text then presents the research on the purification and chemistry of thyroid-stimulating hormone (TSH). Other chapters consider the study of ovine interstitial cell-stimulating hormone, and concentrate to some extent on the very closely related bovine species. This book discusses as well some aspects of the biology of the pituitary interstitial cell-stimulating hormone or luteinizing hormone in mammalian species. The final chapter deals with the correlation of the primary structure with function for a better understanding of the mechanism of action of the hormone at a molecular level.

This book is a valuable resource for biologists, biochemists, and research workers.

Table of Contents

List of Contributors


Contents of Volume II

1. The Chemistry of Glycoproteins



2. The Chemistry of Pituitary Thyrotropin

I. Introduction

II. Preparation of Bovine TSH

III. Purification of Human TSH

IV. The Subunits of Bovine TSH and Their Linear Amino Acid Sequences

V. The Carbohydrate Portion of Bovine TSH

VI. A Comparison of the Molecular Parameters of Bovine TSH Determined Directly and as Deduced from the Sequence

VII. The Chemical and Biological Relationships Between TSH, LH, and HCG (Human Chorionic Gonadotropin)

VIII. Comparative Studies—Human TSH

IX. Problems and Possibilities


3. The Chemistry of the Interstitial Cell-Stimulating Hormone of Ovine Pituitary Origin

I. Introduction

II. Purification of Ovine ICSH

III. Physical Properties of Ovine ICSH

IV. Chemical Properties of Ovine ICSH

V. The Subunit Nature of ICSH

VI. Structural Studies on the ICSH Subunits

VII. Comments on the Heterogeneity of ICSH

VIII. Concluding Remarks


4. The Biology of Pituitary Interstitial Cell-Stimulating Hormone

I. Introduction

II. Gonadotropic Factors of the Pituitary Gland

III. Biological Effects of ICSH in the Female

IV. Role of ICSH in Pregnancy

V. Formation and Maintenance of Corpus Luteum

VI. Biological Effects of ICSH in the Male

VII. Extragonadal Actions of ICSH

VIII. Regulation of ICSH Secretion

IX. Metabolism of ICSH

X. Effects of ICSH on Gonadal Metabolism

XI. Concluding Remarks


5. Chemistry of Huma


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© Academic Press 1973
Academic Press
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About the Editor

Choh Hao Li

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