Hormonal Proteins and Peptides - 1st Edition - ISBN: 9780124472013, 9781483257969

Hormonal Proteins and Peptides

1st Edition

Editors: Choh Hao Li
eBook ISBN: 9781483257969
Imprint: Academic Press
Published Date: 28th August 1973
Page Count: 284
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Description

Hormonal Proteins and Peptides, Volume I reviews extensively the knowledge on the biology and chemistry of the protein and peptide hormones. This book presents the structures of the various protein and peptide hormones.

Organized into five chapters, this volume begins with an overview of the chemistry of several hormonal glycoproteins. This text then presents the research on the purification and chemistry of thyroid-stimulating hormone (TSH). Other chapters consider the study of ovine interstitial cell-stimulating hormone, and concentrate to some extent on the very closely related bovine species. This book discusses as well some aspects of the biology of the pituitary interstitial cell-stimulating hormone or luteinizing hormone in mammalian species. The final chapter deals with the correlation of the primary structure with function for a better understanding of the mechanism of action of the hormone at a molecular level.

This book is a valuable resource for biologists, biochemists, and research workers.

Table of Contents


List of Contributors


Preface


Contents of Volume II


1. The Chemistry of Glycoproteins


Text


References


2. The Chemistry of Pituitary Thyrotropin


I. Introduction


II. Preparation of Bovine TSH


III. Purification of Human TSH


IV. The Subunits of Bovine TSH and Their Linear Amino Acid Sequences


V. The Carbohydrate Portion of Bovine TSH


VI. A Comparison of the Molecular Parameters of Bovine TSH Determined Directly and as Deduced from the Sequence


VII. The Chemical and Biological Relationships Between TSH, LH, and HCG (Human Chorionic Gonadotropin)


VIII. Comparative Studies—Human TSH


IX. Problems and Possibilities


References


3. The Chemistry of the Interstitial Cell-Stimulating Hormone of Ovine Pituitary Origin


I. Introduction


II. Purification of Ovine ICSH


III. Physical Properties of Ovine ICSH


IV. Chemical Properties of Ovine ICSH


V. The Subunit Nature of ICSH


VI. Structural Studies on the ICSH Subunits


VII. Comments on the Heterogeneity of ICSH


VIII. Concluding Remarks


References


4. The Biology of Pituitary Interstitial Cell-Stimulating Hormone


I. Introduction


II. Gonadotropic Factors of the Pituitary Gland


III. Biological Effects of ICSH in the Female


IV. Role of ICSH in Pregnancy


V. Formation and Maintenance of Corpus Luteum


VI. Biological Effects of ICSH in the Male


VII. Extragonadal Actions of ICSH


VIII. Regulation of ICSH Secretion


IX. Metabolism of ICSH


X. Effects of ICSH on Gonadal Metabolism


XI. Concluding Remarks


References


5. Chemistry of Huma

Details

No. of pages:
284
Language:
English
Copyright:
© Academic Press 1973
Published:
Imprint:
Academic Press
eBook ISBN:
9781483257969

About the Editor

Choh Hao Li

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