HLA from Benchtop to Bedside

HLA from Benchtop to Bedside provides the reader with a comprehensive, concise and thoroughly up-to-date book on all aspects of the HLA system, including new techniques and methodologies. Each chapter begins with bullet point lists of principle learning points, including comprehensive references and validated links to international resources. Written by a diverse range of international academics for professionals, researchers, undergraduate and graduate students, this book is ideal for organ and stem cell transplant professionals, histocompatibility laboratory professionals and staff, medical residents and fellows on transplant services, medical students, and students in clinical laboratory science.

The book's author, Dr. Arthur Bradley Eisenbrey, is an experienced transplant pathologist who has held significant academic and leadership positions in the field.

• Reviews current knowledge surrounding the HLA system
• Covers current methodologies and utilization of histocompatibility testing
• Authored by a leader in the field of histocompatibility and transfusion medicine

Organ and stem cell transplant professionals, histocompatibility laboratory professionals and staff, medical residents and fellows on transplant services, medical students and students in clinical laboratory science

1. Introduction and some history
   2. The structure of the Major Histocompatibility Complex and major HLA components
   3. Nomenclature and naming conventions for HLA
   4. The Crossmatch
   5. HLA antibody detection (screening) and identification
   6. HLA typing by serologic methods
   7. HLA typing by molecular methods
   8. Massively parallel (Next Generation) sequencing
   9. HLA alleles, disease associations and HLA pharmacogenetics
   10. Engraftment monitoring