Description

HIV and the New Viruses presents cutting-edge reviews of persistent human virus infections as a coherent collection for the first time. These cover recently discovered viruses such as HHV-6, HHV-8 and HCV, as well as the latest research on HIV. This comprehensive and updated reference includes an in-depth study of the major issues in the epidemiology, pathogenicity, molecular virology, host responses and management of conditions associated with those viruses. Information on new pharmaceuticals and vaccine developments is also included. Edited by the leading experts in the field, HIV and the New Viruses will be essential reading for postgraduates, clinicians and researchers in virology, immunology, cancer, molecular biology and the pharmaceutical industry.

Key Features

@introbul:Key Features @bul:* Presents cutting-edge reviews of persistent human virus infections as a coherent collection for the first time * Includes an in-depth study of the major issues in the epidemiology, pathogenicity, molecular virology, host responses, and management of conditions associated with those viruses

Readership

Research virologists, immunologists, research clinicians, cancer biologists and drug companies; those working in the fields of infectious diseases, autoimmunity, and pathogenesis; those in related areas such as cell and molecular biology and medicinal chemistry.

Table of Contents

A. Dalgleish and R. Weiss, Preface. A. Alonso & M. Peterlin, HIV-1: Control of Gene Expression by the Viral Regulatory Proteins Tat and Rev. A. Leigh-Brown, Viral Evolution and Variation in the HIV Pandemic. H. Schuitemaker, Biological Phenotypes of HIV-1 and Their Relevance for AIDS Pathogeneis. A. Philips, HIV Dynamics: Lessons From Use of Antiretrovirals. S. McAdam and F. Gotch, The Cytotoxic T Lymphocyte Response to the Immunodeficiency Viruses. D. Fenoglio, G. Li Pira and F. Manca, T Helper Cells Specific For Retroviral Epitopes. M.L. Gougeon and K.-M. Debatin, Molecular Control of Programmed Cell Death in Human Immunodeficiency Virus Infection. Contribution to the Dysregulation of T Cell Homeostasis and to CD4 T Cell Depletion. M Clerici, A. Clivio and G.M. Shearer, The Relationships Between Cytokines, Complement and HIV Disease. M.A. Norcross, Chemokine Receptors and HIV-1 Pathogenesis: A Viral Fatal Attraction. D.L. Mann, HLA and HIV-1 Infection. A.G. Dalgleish, E. Hounsell and H. Baum, The Potential Role of HLA Mimicry in the Pathogenesis of AIDS. I. Weller, The Impact of Antiviral Therapy on HIV Disease. N. Berry and R. Tedder, HIV I & HIV II Molecular Diagnosis. M.A. Wainberg, HIV Resistance to Antagonists of Viral Reverse Transcriptase, L. Rosenblum and M. McClure, Non-Lontiviral Primate Retroviruses. A. Gessain and R. Mahieux, Genetic Diversity and Molecular Epidemiology of Human T Cell Leukemia/Lymphoma Viruses Type 1 and Type 2 and Related Simian Retroviruses (STLV-1, STLV-2 pan-p and PTLV L). M.K. Williams and P. Lusso, Human Herpesvirus 6 (HHV-6). S. Talbot and D. Whitb

Details

No. of pages:
554
Language:
English
Copyright:
© 1999
Published:
Imprint:
Academic Press
Print ISBN:
9780122007415
Electronic ISBN:
9780080534084

About the authors

Angus Dalgleish

Angus Dalgleish is a professor of Oncology at the Institute of Cancer Research in London, UK

Affiliations and Expertise

St. George's Hospital Medical School, Cranmer Terrace, London, U.K.

Robin Weiss

Robin Weiss is a professor of Viral Oncology at University College London Medical School. Previously he was at the Institute of Cancer Research in London, UK He is an authority on retroviruses infecting humans and animals, and has a special interest in cell surface receptors for viruses.

Affiliations and Expertise

University College London, U.K.

Reviews

"...provides up-to-date reviews on these important issues on HIV research that have emerged during the last 10 years." @source:--Phalguni Gupta, University of Pittsburgh, in ASM NEWS (2000) @qu:"This is a comprehensive and up-to-date volume that reviews our current knowledge of HIV and other recently identified viruses of humans. ...I found the chapters to be detailed and well written with a healthy supply of illustrations to aid understanding." @source:--MICROBIOLOGY TODAY (November 1999) @qu:"I highly recommend this volume to clinicians and virologists... It will be rewarding." @source:--INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY @from:PRAISE FOR THE FIRST EDITION @qu:"...Each chapter presents a clear, authoritative and up-to-date account of the subject..." @source:--IMMUNOLOGY @qu:"... Well written and illustrated... An excellent series of reviews... Should be of interest to virologists, immunologists and clinicians at all levels." @source:--AIDS CARE, Clive Loveday, University College and Middelsex School of Medicine, London