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History of Modern Clinical Toxicology - 1st Edition - ISBN: 9780128222188

History of Modern Clinical Toxicology

1st Edition

Editor: Alan Woolf
Paperback ISBN: 9780128222188
Imprint: Academic Press
Published Date: 1st October 2021
Page Count: 300
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Table of Contents

SECTION 1. U.S. POISON CONTROL MOVEMENT
1.1 Poison Control Centers Get Organized
1.2 Poison Control Centers: Consolidation and Change
1.3 New Age: Information Technology 1990’s
1.4 Progress in Poison Prevention

SECTION 2. ORGANIZING U.S. PROFESSIONAL SOCIETIES
2.1. Promoting Clinical Toxicology Professionalism
A. Growing Interest in Toxicology – 20th Century
B. Formalizing the Profession
2.2 Growth of American Societies

SECTION 3. MEDICAL THERAPIES AND MODERN ANTIDOTES
3.1 Progress in Medical Therapies
3.1.1 Preventing Poison Absorption
3.1.2 Enhancing Poison Elimination
3.2 History of Discovery: Selected Antidotes
3.2.1 British Anti-Lewisite (BAL)
3.2.2 Fomepizole
3.2.3 N-Acetyl Cysteine
3.2.4 Cupramine
3.2.5 Cyanide Antidotes
3.2.6 Digoxin Fab Antibodies
3.2.7 Deferoxamine
3.2.8 Pyridoxine
3.2.9 CROFab

SECTION 4. DISASTERS: TOXIC CALAMITIES FROM AROUND THE WORLD
4.1 Tri-Ortho Cresyl Phosphate (TOCP) ‘Ginger Jake’ Disaster – United States - 1930
4.2 Methyl-mercury Poisoning – Minamata Bay, Japan - 1956
4.3 Community Dioxin Disaster - Seveso Italy - 1976
4.4 Arsenic Tube Well Water Poisonings – Bangladesh 1970’s-1990’s
4.5 Methyl-Mercury Grain Fungicide Poisoning – Iraq - 1971
4.6.1 Toxic Oil Syndrome – Spain – 1970s
4.6.2 Eosinophilia-Myalgia Syndrome – United States – October 1989
4.7 Union Carbide Methyl-Isocyanate Gas Leak – Bhopal, India - 1984
4.8 Zamfura Gold Mining Lead Poisoning Disaster – Africa 2000

SECTION 5. CANADIAN CLINICAL TOXICOLOGY
5.1 Organization of Canadian Poison Control

SECTION 6. NOTABLE PHARMACEUTICAL POISONING INCIDENTS
6.1 Sulfanilamide (Diethylene Glycol) Disaster – United States, 1937
6.1.1 Haitian acetaminophen poisoning event
6.2 Gasping baby syndrome Neonatal Gasping Syndrome & benzyl alcohol poisoning – 1980’s
6.3 Tylenol tampering cyanide poisoning Chicago IL Sept 29, 30 1982
6.4 Goiãnia, Brazil, South America – 1987

SECTION 7. NOTABLE POISONED PEOPLE
7.1 Notables
7.2 Jonestown People’s Temple
7.3 Modern Political Poisonings

SECTION 8. KEY POLICIES AND AGENCIES
8.1 Key Agencies
8.2 Key Policies in the History of Clinical Toxicology

SECTION 9. INNOVATIONS AND NEW DIRECTIONS
9.1 Professional Education
9.2 Internet-Based Poison Control Resources
9.3 Genetics
9.4 Environmental Toxicology
9.5 Toxicology Treatment Centers
9.6 New Toxins, Antidotes
9.7 Toxicology Testing in the 21st Century


Description

History of Modern Clinical Toxicology describes extraordinary advances in the practice of clinical toxicology within the past 70 years, bringing together stories of those who contributed and those who discovered new therapies and antidotes and made change happen. The book lays out the poison control system and the fascinating story of how they created a new and evolving medical specialty. In addition, the book tells the stories of modern-day toxic disasters that led to improvements in our understanding of the science. Finally, the book covers key policies and agencies, addresses the challenges facing clinical toxicologists, and predicts future advances.

This book is a unique resource with an historical and international perspective that will help practitioners put current issues and methods in perspective while also giving readers an understanding on how infrastructure and processes have evolved.

Key Features

  • Offers descriptions of the key regulatory advances affecting clinical toxicology
  • Provides synopses of modern-day poisoning disasters
  • Outlines the development of modern antidotes and future directions in clinical toxicology

Readership

Researchers, academics, and professional toxicologists; clinicians and other health care providers; poison control center workers, poison control centers; emergency medicine practitioners. Graduate students in clinical and medical toxicology; organizations involved in incident control and management for chemical and large-scale events; regulators


Details

No. of pages:
300
Language:
English
Copyright:
© Academic Press 2021
Published:
1st October 2021
Imprint:
Academic Press
Paperback ISBN:
9780128222188

Ratings and Reviews


About the Editor

Alan Woolf

Alan Woolf

Dr. Alan Woolf has been the Director of the Region 1 Pediatric Environmental Health Specialty Unit, a facility that offers consultation to health professionals and the public about clinical topics in environmental toxicology, for more than 20 years. He was also the Medical Director of the Massachusetts/Rhode Island Poison Control Center for 18 years. He is a former president of the American Academy of Clinical Toxicology and the American Association of Poison Control Centers, the two premier clinical toxicology societies in America. Dr. Woolf is a Professor of Pediatrics, Harvard Medical School (HMS), Director of the Environmental Medicine program, attending physician at Boston Children’s Hospital (BCH), and a member of both the Academy at HMS and the Teaching Academy at BCH. Dr. Woolf and his colleagues research includes topics in clinical toxicology, medical therapies in the management of childhood poisonings, and topics in poisoning epidemiology and prevention.

Affiliations and Expertise

Director, Pediatric Environmental Health Center, BCH; Director, Region 1 New England Pediatric Environment Health Specialty Unit; Associate Chief Medical Education Officer and DIO, BCH, Professor of Pediatrics, Harvard Medical School