
Histopathology of Preclinical Toxicity Studies
Interpretation and Relevance in Drug Safety Evaluation
Description
Key Features
- This edition is in full color and features nearly 200 high-quality images
- Provides extended commentary on the relevance of pathological findings and features a fully updated bibliography containing sources for further reading
- Includes new content coverage on the commonly used transgenic animal models that are used in safety assessment, specific tumor types induced by drugs in rodents, and new drug-induced pathologies and lesions
Readership
Clinical toxicologists, pathologists, and pharmacologists involved professionally in drug safety evaluation and especially those researchers working in pharmaceutical companies, contract laboratories and in government agencies
Table of Contents
Chapter 1. Introduction
References
Chapter 2. Integumentary System
Skin and subcutaneous tissue
References
Chapter 3. Mammary Gland
References
Chapter 4. Hemopoietic and Lymphatic Systems
Blood and bone marrow
Lymphoid system
Lymph nodes
Spleen
Thymus
Lymphoreticular neoplasms
References
Chapter 5. Musculoskeletal System
Bone
Joints
Skeletal muscle
References
Chapter 6. Respiratory Tract
Nose, nasal sinuses, nasopharynx and pharynx
Larynx and trachea
Bronchi and lungs
References
Chapter 7. Cardiovascular System
Heart and pericardium
Systemic blood vessels
Pulmonary blood vessels
References
Chapter 8. Digestive System
Mouth and oropharynx
Salivary glands
Esophagus
Forestomach
Stomach (glandular)
Small intestine
Large intestine
References
Chapter 9. Liver and Pancreas
Liver
Bile ducts, biliary system
Gallbladder
Exocrine pancreas
Endocrine Pancreas
References
Chapter 10. Urinary Tract
Kidney
Urinary bladder
Neoplasia
References
Chapter 11. Male Genital Tract
Prostate gland
Preputial (and clitoral) glands
Epididymis
Testis
References
Chapter 12. Female Genital Tract
Clitoral glands
Vagina
Cervix
Uterus
Ovary
References
Chapter 13. Endocrine Glands
Pituitary gland
Adrenal gland
Thyroid gland
Parathyroid gland
References
Chapter 14. Nervous System and Special Sense Organs
Brain
Spinal cord, spinal nerve roots and peripheral nerves
Eye
Ear
References
Index
Product details
- No. of pages: 892
- Language: English
- Copyright: © Academic Press 2011
- Published: October 7, 2011
- Imprint: Academic Press
- eBook ISBN: 9780444538611
- Hardcover ISBN: 9780444538567
About the Author
Peter Greaves

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