High-LET Radiations in Clinical Radiotherapy

High-LET Radiations in Clinical Radiotherapy

Proceedings of the 3rd Meeting on Fundamental and Practical Aspects of the Application of Fast Neutrons and Other High-LET Particles in Clinical Radiotherapy, The Hague, Netherlands, 13—15 September 1978

1st Edition - January 1, 1979

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  • Editors: G. W. Barendsen, J. J. Broerse, K. Breur
  • eBook ISBN: 9781483189086

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Description

High-LET Radiations in Clinical Radiotherapy covers the proceedings of the 3rd Meeting on Fundamental and Practical Aspects of the Application of Fast Neutrons and other High-LET Particles in Clinical Radiotherapy. The title presents papers that report the experiences in utilizing High-LET radiations in clinical radiotherapy. The coverage of the text includes observations on the reactions of normal and malignant tissues to a standard dose; and clinical observations of early and late normal tissue injury and tumor control in patients receiving fast neutron irradiation. The selection also covers results of fast neutron radiotherapy at Amsterdam; and results of clinical applications with fast neutrons in Edinburgh. The book will be of great use to students and practitioners of medical technology.

Table of Contents


  • Introduction to the Proceedings

    Sessions I and II. Reports on Clinical Experience

    Second Preliminary Report of the M. D. Anderson Study of Neutron Therapy for Locally Advanced Gynecological Tumors

    Observations on the Reactions of Normal and Malignant Tissues to a Standard Dose of Neutrons

    Results of Fast Neutron Radiotherapy at Amsterdam

    Results of Fast Neutron Beam Radiotherapy Pilot Studies at the University of Washington

    Results of Clinical Applications with Fast Neutrons in Edinburgh

    Fast Neutron Project at Fermilab

    Clinical Observations of Early and Late Normal Tissue Injury and Tumor Control in Patients Receiving Fast Neutron Irradiation

    Results of Clinical Applications of Fast Neutrons at Hamburg-Eppendorf

    Results of Clinical Applications of Negative Pions at Los Alamos

    Results of Tumor Treatments with Alpha Particles and Heavy Ions at Lawrence Berkeley Laboratory

    Results of Clinical Applications of Fast Neutrons in Japan

    Five Years of Clinical Experience with a Combination of Neutrons and Photons

    Hyperbaric Oxygen and Hypoxic Cell Sensitizers in Clinical Radiotherapy: Present State and Prospects

    Treatment at Low Dose Rate, by Low-LET Radiation: Present Status and Prospects

    Combined Chemo/Radiotherapy of Cancer: Present State and Prospects for Use with High-LET Radiotherapy

    Sessions III and IV. Physical Aspects and Radiobiology

    Review of Performance of High-LET Radiation Sources Used in Clinical Applications

    Dose Distributions of Clinical Fast Neutron Beams

    Dosimetry Intercomparisons and Protocols for Therapeutic Applications of Fast Neutron Beams

    Characteristics of Fast Neutron Sources

    Contributions on Characteristics of Fast Neutron Sources

    Neutron Dosimetry, Radiation Quality and Biological Dosimetry

    Contributions on Neutron Dosimetry, Radiation Quality and Biological Dosimetry

    Review of RBE Data for Cells in Culture

    RBE Values of Fast Neutrons for Responses of Experimental Tumors

    Neutron RBE for Normal Tissues

    Fast Neutron Radiobiology

    Contributions on fast Neutron Radiobiology

    Dosimetry and Radiobiology of Negative Pions and Heavy Ions

    Contributions on Dosimetry and Radiobiology of Negative Pions and Deavy Ions

    The Committee on Radiation Oncology Studies Plan for a Program in Particle Therapy in the United States

    Sessions V and VI. Evaluation of Present Results and Future of High LET Radiotherapy

    Evaluation of Clinical Experience Concerning Evaluation of Tumor Response to High-LET Radiation

    Evaluation of Normal Tissue Responses to High-LET Radiations

    The Application of RBE Values to Clinical Trials of High-LET Radiations

    Doses and Fractionation Schemes to Be Employed in Clinical Trials of High-LET Radiations

    Review of Protocols for High-LET Radiotherapy in the United States

    Clinical Trials with Fast Neutrons in Europe

    Summary of Discussion on Multi-Center Collaboration in Clinical Trials with High-LET Radiations

    Concluding Remarks on the Future of High-LET Radiotherapy

    List of Participants of the 3rd Meeting on Fundamental and Practical Aspects of the Application of Fast Neutrons and Other High-LET Particles in Clinical Radiotherapy


Product details

  • No. of pages: 298
  • Language: English
  • Copyright: © Pergamon 1979
  • Published: January 1, 1979
  • Imprint: Pergamon
  • eBook ISBN: 9781483189086

About the Editors

G. W. Barendsen

J. J. Broerse

K. Breur

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