Herpes Simplex Varicella and Zoster

Herpes Simplex Varicella and Zoster

Clinical Manifestations and Treatment

1st Edition - January 1, 1972

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  • Authors: B. E. Juel-Jensen, F. O. Maccallum
  • eBook ISBN: 9781483163154

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Herpes Simplex Varicella and Zoster: Clinical Manifestations and Treatment provides an authoritative and updated clinical observation on two viruses—herpes simplex varicella and zoster. This book focuses on the similarities in tissue tropisms and character of the lesions of the two viruses. This text not only outlines the various disease patterns but gives guidance to rational treatment with antiviral agents. The topics covered include the historical background of the two viruses; description and clinical manifestations of infection in man of herpes simplex (HSV) and varicella-zoster (V-Z); definition of B virus (herpesvirus simiae); recurrent infection zoster; and treatment. This publication is intended for clinicians, but can also be a good reference for medical students and individuals conducting research in the field of virology, specifically on venereal diseases.

Table of Contents

  • Preface


    1. Historical Background

    2. Herpes Simplex

    The Virus


    Morphology and Replication

    Herpes Antigenic Types

    Pathology and Pathogenesis

    HSV and Carcinoma

    Laboratory Diagnosis


    Immunity and Recovery

    3 Clinical Manifestations of HSV Infection

    The Primary Infection


    Primary Infection of the Mouth and Lips

    Ocular Infection with HSV

    Primary Lesions of the Skin

    Herpetic Whitlows

    Traumatic Herpes

    Eczema Herpeticum. Juliusberg's Pustulosis Acuta Varioliformis. Kaposi's Varicelliform Eruption

    Generalized Primary Infections

    Hepatitis due to HSV

    HSV Meningitis

    HSV Encephalitis

    The Recurrent Infection

    Complications in Recurrent HSV Infections

    Herpesvirus Infection in Burned Patients

    Recurrent Herpes Simplex and Erythema Multiforme

    Genital Herpes Simplex Infections

    Differential Diagnosis

    4. B Virus Infection


    The Virus


    Laboratory Diagnosis

    Antigenic Relationship with HSV

    5. Varicella-Zoster

    The Virus


    Morphology and Replication

    Pathology and Pathogenesis

    Laboratory Diagnosis


    Immunity and Recovery

    6. Clinical Manifestations of V-Z Virus Infection

    Chickenpox. Varicella

    Epidemiology and Infectivity

    Clinical Manifestations

    Differential Diagnosis from Smallpox


    Varicella pneumonias


    Purpura Fulminans. Haemorrhagic Chickenpox

    Congenital and Neonatal Varicella

    7. The Recurrent Infection

    Zoster. Shingles


    Provocation of Zoster

    The Usual Clinical Picture in Zoster

    Pain in Zoster

    Dissemination of Virus in Zoster

    The Segmental Distribution of Zoster and some Complications

    Recurrent Zoster

    Ophthalmic Zoster

    Motor Zoster

    Zoster Encephalomyelitis

    8 Treatment

    Some Problems in Antiviral Chemotherapy

    Halogenated Deoxyuridines Idoxuridine; 5-iodo-2'-deoxyuridine; IUdR; IDU

    D-Arabinofuranosyl Nucleotides

    1-β-D arabinofuranosylcytosine (cytarabine; cytosine arabinoside; CA; Ara-C)

    9-β-D arabinofuranosyladenine (vidarabine; adenosine arabinoside; adenine arabinoside; Ara-A)

    Treatment of HSV Infection

    Cold Sores

    HSV Gingivostomatitis

    Severe HSV Stomatitis

    Ocular HSV Lesions

    Herpetic Whitlows

    Erythema Multiforme provoked by Recurrent HSV Lesions

    Eczema Herpeticum

    Generalized HSV Infection

    HSV Encephalitis

    Genital Herpes

    Treatment of B Virus Infection

    Treatment of V-Z Infection


    Uncomplicated Segmental Zoster

    Ophthalmic Zoster

    Motor Zoster

    Generalized Zoster

    Zoster Encephalitis

    Chickenpox, Zoster and HSV Infections during Pregnancy



Product details

  • No. of pages: 206
  • Language: English
  • Copyright: © Butterworth-Heinemann 1972
  • Published: January 1, 1972
  • Imprint: Butterworth-Heinemann
  • eBook ISBN: 9781483163154

About the Authors

B. E. Juel-Jensen

F. O. Maccallum

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