Hematology

6th Edition

Basic Principles and Practice, Expert Consult Premium Edition - Enhanced Online Features and Print

Authors:

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Table of Contents

PART I: Molecular and Cellular Basis of Hematology

1 Anatomy and Pathophysiology of the Gene

2 Genomic Approaches to Hematology

3 Regulation of Gene Expression, Transcription, Splicing, and RNA Metabolism

4 Protein Synthesis, Processing, and Trafficking

5 Protein Architecture: Relationship of Form and Function

6 Signaling Transduction and Regulation of Cell Metabolism

7 Pharmacogenomics and Hematologic Diseases

PART II: Cellular Basis of Hematology

8 Hematopoietic Stem Cell Biology

9 Hematopoietic Microenvironment

10 Cell Adhesion

11 Hematopoietic Cell Trafficking and Chemokines

12 Dynamic Interactions between Hematopoietic Stem and Progenitor Cells and the Bone Marrow: Current Biology of Stem Cell Homing and Mobilization

13 Vascular Growth in Health and Disease

14 Principles of Cytokine Signaling

15 Control of Cell Division

16 Cell Death

PART III: Immunologic Basis of Hematology

17 Overview and Compartmentalization of the Immune System

18 B-Cell Development

19 T-Cell Immunity

20 Natural Killer Cell Immunity

21 Dendritic Cell Biology

22 Complement and Immunoglobulin Biology

23 Tolerance and Autoimmunity

PART IV: Disorders of Hematopoietic Cell Development

24 Biology of Erythropoiesis, Erythroid Differentiation, and Maturation

25 Granulocytopiesis and Monocytopoiesis

26 Thrombocytopoiesis

27 Inherited Forms of Bone Marrow Failure

28 Aplastic Anemia

29 Paroxysmal Nocturnal Hemoglobinuria

30 Acquired Disorders of Red Cell, White Cell, and Platelet Production

PART V: Red Blood Cells

31 Pathobiology of the Human Erythrocyte and Its Hemoglobins

32 Approach to Anemia in the Adult and Child

33 Pathophysiology of Iron Homeostasis

Details

No. of pages:
2384
Language:
English
Copyright:
© 2013
Published:
Imprint:
Churchill Livingstone
eBook ISBN:
9780323246934
eBook ISBN:
9781455740413
Print ISBN:
9781437729283

About the authors

Ronald Hoffman

Affiliations and Expertise

Albert A. and Vera G. List Professor of Medicine, Tisch Cancer Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York

Edward Benz

Affiliations and Expertise

Richard and Susan Smith Professor of Medicine, Professor of Pediatrics and Genetics, Harvard Medical School; President and CEO, Dana-Farber Cancer Institute Director and Principal Investigator Dana Farber/Harvard Cancer Center, Boston, Massachusetts

Leslie Silberstein

Affiliations and Expertise

Professor of Pathology (Pediatrics), Director, Joint Program in Transfusion Medicine, Harvard Medical School, Boston, Massachusetts

Helen Heslop

Affiliations and Expertise

Professor, Departments of Medicine and Pediatrics Section of Hematology-Oncology, Baylor College of Medicine; Dan L. Duncan Chair Director, Adult Stem Cell Transplant Program, The Methodist Hospital; Associate Director Clinical Research, Dan L. Duncan Cancer Center; Houston, Texas

Jeffrey Weitz

Affiliations and Expertise

Professor of Medicine and Biochemistry and Biomedical Sciences, McMaster University, Heart and Stroke Foundation/J.F. Mustard Chair in Cardiovascular Research Canada Research Chair (Tier 1) in Thrombosis, Executive Director, Thrombosis & Atherosclerosis Research Institute (TaARI), Hamilton General Hospital, Hamilton, Ontario, Canada

John Anastasi

Affiliations and Expertise

Associate Professor; Assistant Director, Hematopathology; Medical Director, Flow Cytometry; Department of Pathology, The University of Chicago; Chicago, Illinois