6th Edition

Basic Principles and Practice, Expert Consult Premium Edition - Enhanced Online Features and Print


  • Helen Heslop
  • Ronald Hoffman
  • Leslie Silberstein
  • Edward Benz
  • John Anastasi
  • Jeffrey Weitz
  • Key Features

    • Make confident, effective clinical decisions by consulting the world's most trusted hematology reference.
    • Access the complete contents online at www.expertconsult.com, with a downloadable image collection, regular updates, case studies, patient information sheets, and more.

    Table of Contents

    PART I: Molecular and Cellular Basis of Hematology

    1 Anatomy and Pathophysiology of the Gene

    2 Genomic Approaches to Hematology

    3 Regulation of Gene Expression, Transcription, Splicing, and RNA Metabolism

    4 Protein Synthesis, Processing, and Trafficking

    5 Protein Architecture: Relationship of Form and Function

    6 Signaling Transduction and Regulation of Cell Metabolism

    7 Pharmacogenomics and Hematologic Diseases

    PART II: Cellular Basis of Hematology

    8 Hematopoietic Stem Cell Biology

    9 Hematopoietic Microenvironment

    10 Cell Adhesion

    11 Hematopoietic Cell Trafficking and Chemokines

    12 Dynamic Interactions between Hematopoietic Stem and Progenitor Cells and the Bone Marrow: Current Biology of Stem Cell Homing and Mobilization

    13 Vascular Growth in Health and Disease

    14 Principles of Cytokine Signaling

    15 Control of Cell Division

    16 Cell Death

    PART III: Immunologic Basis of Hematology

    17 Overview and Compartmentalization of the Immune System

    18 B-Cell Development

    19 T-Cell Immunity

    20 Natural Killer Cell Immunity

    21 Dendritic Cell Biology

    22 Complement and Immunoglobulin Biology

    23 Tolerance and Autoimmunity

    PART IV: Disorders of Hematopoietic Cell Development

    24 Biology of Erythropoiesis, Erythroid Differentiation, and Maturation

    25 Granulocytopiesis and Monocytopoiesis

    26 Thrombocytopoiesis

    27 Inherited Forms of Bone Marrow Failure

    28 Aplastic Anemia

    29 Paroxysmal Nocturnal Hemoglobinuria

    30 Acquired Disorders of Red Cell, White Cell, and Platelet Production

    PART V: Red Blood Cells

    31 Pathobiology of the Human Erythrocyte and Its Hemoglobins

    32 Approach to Anemia in the Adult and Child

    33 Pathophysiology of Iron Homeostasis


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    © 2013
    Churchill Livingstone
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