Head and Neck Cutaneous Cancer, An Issue of Otolaryngologic Clinics of North America

1st Edition, Volume 54-2 - March 23, 2021
Editors: Cecelia E Schmalbach, Kelly M. Malloy
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 8 1 3 1 7 - 4
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 8 1 3 1 8 - 1

This issue of Otolaryngologic Clinics, guest edited by Drs. Cecelia E. Schmalbach and Kelly M. Malloy, is dedicated to Head and Neck Cutaneous Cancer. This issue is one of six… Read more

Head and Neck Cutaneous Cancer, An Issue of Otolaryngologic Clinics of North America

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This issue of Otolaryngologic Clinics, guest edited by Drs. Cecelia E. Schmalbach and Kelly M. Malloy, is dedicated to Head and Neck Cutaneous Cancer. This issue is one of six selected each year by the series Consulting Editor, Dr. Sujana S. Chandrasekhar. Cutaneous cancer rates are growing at epidemic proportions and consequently lead to a significant health care burden. This issue opens with an overview of the related biology, epidemiology, and preventative measures. A contemporary review of cutaneous cancer management will be provided to include the roles of sentinel node biopsy, surgery, radiation therapy, and systemic therapy. Cutaneous cancers impact the geriatric patient population, so ethical considerations and non-surgical management are emphasized.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Foreword
Preface
Epidemiology and Prevention of Cutaneous Cancer
Key points
Incidence
Risk factors
Immune system factors
Prevention
Screening
CLINICS CARE POINTS
Cutaneous Cancer Biology
Key points
Cutaneous squamous cell carcinoma
Basal cell carcinoma
Melanoma
Merkel cell carcinoma
Molecular signaling in skin cancer
Epidermal growth factor receptor
Fibroblast growth factor receptor
Summary
Clinics care points
Management of Advanced Basal Cell Carcinoma of the Head and Neck
Key points
Introduction
Discussion
Surgical therapy
Radiation
Systemic therapy for basal cell carcinoma
Summary
Clinics care points
Sentinel Node Biopsy for Head and Neck Cutaneous Melanoma
Key points
Introduction
Sentinel lymph node biopsy: a brief history
Early technique
Multicenter Selective Lymphadenectomy Trial
Head and neck melanoma: a unique subsite
Current indications for sentinel lymph node biopsy
Management of the neck after a positive sentinel node: the new debate
The German Dermatologic Cooperative Oncology Group Selective Lymphadenectomy Trial
The second Multicenter Selective Lymphadenectomy Trial
To dissect or observe the neck?
Summary
Sentinel Node Biopsy for Nonmelanoma Skin Cancer of the Head and Neck
Key points
Introduction
Considerations for cutaneous squamous cell carcinoma
Considerations for Merkel cell carcinoma
Considerations for other nonmelanoma skin cancers
Summary
Clinics Care Points
Radiation Therapy for Cutaneous Malignancies of the Head and Neck
Key points
Introduction
Basal cell carcinoma
Cutaneous squamous cell carcinoma
Cutaneous melanoma
Merkel cell carcinoma
Summary
The Role of Systemic Therapy in Advanced Cutaneous Melanoma of the Head and Neck
Key points
Introduction
Systemic therapy
Summary
Clinics care points
The Role of Systemic Therapy in Advanced Cutaneous Squamous Cell Carcinoma
Key points
Introduction
Definition of advanced cutaneous squamous cell carcinoma
Systemic agents used to treat advanced cutaneous squamous cell carcinoma
Indications and applications for systemic therapy for advanced cutaneous squamous cell carcinoma
Locally advanced unresectable disease and metastatic disease
Summary
Clinics care points
Surgical Management of Merkel Cell Carcinoma
Key points
Introduction
Etiology and risk factors
Diagnosis, staging, prognosis
Surgical management: early-stage disease (stages I and II)
Surgical management: stage III
Surgical management of unknown primary Merkel cell carcinoma
Role of adjuvant radiotherapy
Role of systemic therapy
Cutaneous Sarcomas
Key points
Dermatofibrosarcoma protuberans
Atypical fibroxanthoma
Pleomorphic dermal sarcoma
Cutaneous leiomyosarcoma
Angiosarcoma
Summary
Reconstruction of Cutaneous Cancer Defects of the Head and Neck
Key points
Introduction
Healing by secondary intention
Skin and composite graft physiology
Skin flap physiology
Forehead and scalp
Ocular adnexa
Nose
Cheek
Perioral reconstruction
Chin
Ear
Skin expansion
Complications
Clinics Care Points
Cutaneous Head and Neck Cancers in the High-Risk Immunosuppressed Population
Key points
Introduction
Pathogenesis
Incidence and prognosis
Risk factors unique to the immunosuppressed population
Staging
Cutaneous cancer treatment of immunosuppressed patients
Prevention
Summary
Ethical Considerations for Elderly Patients with Cutaneous Malignancy
Key points
Introduction
Background
Case studies
Summary
Clinics care points
Injectables in Head and Neck Cutaneous Melanoma Treatment
Key points
Introduction: melanoma in otolaryngology
Summary
Clinics care points
The Role of Mohs Surgery in Cutaneous Head and Neck Cancer
Key points
Introduction
Application of Mohs micrographic surgery in the head and neck
Summary
Clinics care points
Special Article Series: Intentionally Shaping the Future of Otolaryngology
Special Foreword
Special Preface
Mentorship and Sponsorship in a Diverse Population
Key points
Introduction
Mentorship and sponsorship defined
Current state of mentorship in otolaryngology
Strategies for mentors and sponsors
Strategies for mentees
Specific mentorship and sponsorship needs among diverse populations
Summary
Increasing the Number of Black Otolaryngologists
Key points
Introduction
History
Discussion
Summary

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Cecelia E Schmalbach

Kelly M. Malloy