Hayes' Handbook of Pesticide Toxicology

Hayes' Handbook of Pesticide Toxicology

Principles and Agents

3rd Edition - January 6, 2010

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  • Editor-in-Chief: Robert Krieger
  • eBook ISBN: 9780080922010
  • Hardcover ISBN: 9780123743671

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The Handbook of Pesticide Toxicology is a comprehensive, two-volume reference guide to the properties, effects, and regulation of pesticides that provides the latest and most complete information to researchers investigating the environmental, agricultural, veterinary, and human-health impacts of pesticide use. Written by international experts from academia, government, and the private sector, the Handbook of Pesticide Toxicology is an in-depth examination of critical issues related to the need for, use of, and nature of chemicals used in modern pest management. This updated 3e carries on the book’s tradition of serving as the definitive reference on pesticide toxicology and recognizes the seminal contribution of Wayland J. Hayes, Jr., co-Editor of the first edition.

Key Features

  • Presents a comprehensive look at all aspects of pesticide toxicology in one reference work.
  • Clear exposition of hazard identification and dose response relationships in each chapter featuring pesticide agents and actions
  • All major classes of pesticide considered
  • Different routes of exposure critically evaluated


Libraries and institutions, hospitals, medical wholesalers. Researchers in toxicology, agriculture and public health

Table of Contents

  • Volume 1:

    1. Dose, Time and Other Factors Influencing Toxicity

    2. Pest Toxicology: The Mechanisms of Pesticide Action

    3. Pest Control Agents from Natural Products

    4. Public Health Pesticides

    5. The Changing Role of insecticides in Structural Pest Control

    6. Vertebrate Pest Control Chemicals and Their Use in Urban and Rural Environments

    7. Pesticide Use and Associated Morbidity and Mortality in Veterinary Medicine

    8. Pesticide Use Practices in Integrated Pest Management

    9. Properties of Soil Fumigants and Their Fate in the Environment

    10. Risk Assessment for Acute Exposure to Pesticides

    11. Genotoxicity of Pesticides

    12. Developmental and Reproductive Toxicology of Pesticides

    13. Microbial Pest Control Agents: Use Patterns, Registration Requirements and Mammalian Toxicity

    14. The Assessment of the Chronic Toxicity and Carcinogenicity of Pesticides

    15. Immunotoxicity of Pesticides

    16. Risk Assessment for Acute, Subchronic and Chronic Exposure to Pesticides: Endosulfan

    17. Genetic Polymorphism and Susceptibility to Pesticides

    18. Pesticides as Endocrine-Disrupting Chemicals

    19. Volatile Organic Compounds from Pesticide Application and Contribution to Tropospheric Ozone

    20. Environmental Transport and Fate

    21. Proteomics in Pesticide Toxicology

    22. Metabolomics in Pesticide Toxicology

    23. Irritant Dermatitis Syndrome

    24. Photoirritation

    25. Allergic Contact Dermatitis

    26. Contact Urticaria Syndrome

    27. Percutaneous Penetration

    28. Regulatory Evaluation of the Skin Effects of Pesticides

    29. Neurotoxicology of Pesticides

    30. A Systems Biology Approach to Assess the Impact of Pesticides on the Nervous System

    31. Neurophysiological Effects of Insecticides

    32. Age and Pesticide Toxicity: The Influence of Age on Pesticide Toxicity

    33. Lasting Behavioral Consequences of Organophosphate Pesticide Exposure During Development

    34. The Nonhuman Primate as a Translational Model for Pesticide Research

    35. Pesticide Disposition

    36. Introduction to Biotransformation

    37. Absorption

    38. Metabolism of Pesticides

    39. Distribution and Pharmacokinetics

    40. Metabolic Interactions of Pesticides

    41. Pesticide Excretion

    42. Exposure Framework

    43. Sampling and Analysis for Non-Occupational Pesticide Exposure Assessments

    44. Modelling and Predicting Pesticide Exposures

    45. Biomonitoring: Current Tools and Approaches for Assessing Human Exposures to Pesticides

    46. Pesticide Exposure from Residential and Recreational Turf

    47. Lawn and Turf: Management and Environmental Issues of Turfgrass Pesticides

    48. Pet Care Products Used for Insect Pest Control

    49. Residential Exposure Assessment

    50. Modeling Dietary Exposure with Special Sections on Modeling Aggregate and Cumulative Exposure

    51. Modeling Dietary Exposure with Special Sections on Modeling Aggregate and Cumulative Exposure

    52. Worker Exposure: Methods and Techniques

    53. Operator and Field Worker Occupational Exposure Databases and Modeling

    54. Mitigation Measures for Exposure to Pesticides

    55. Regional and Global Environmental Exposure Assessments - Section Introduction

    56. Ecotoxicological Risk Assessment of Pesticides the Environment

    57. Environmental Transport and Fate

    58. Hydrophobicity as a Key Physicochemical Parameter of Environmental Toxicology of Pesticides (Fujita et al.)

    59. Pesticide Studies in Humans

    60. Diagnosis and Treatment of Poisoning Due to Pesticides

    61. Surveillance of Pesticide-Related Illness and Injury in Humans

    62. Risk Assessment and Risk Management: The Regulatory Process

    63. Perceptions of Pesticides as Risks to Human Health

    Volume 2:

    64. Chemistry of Organophosphorus Insecticides

    65. The Metabolism of Organophosphorus Insecticides

    66. Organophosphorus Insecticide Pharmacokinetics

    67. Neuropathy Target Esterase

    68. Cholinesterases

    69. Organophosphorus-Induced Delayed Neuropathy

    70. Chlorpyrifos

    71. Malathion – A Review of Toxicology

    72. Clinical Toxicology of Anticholinesterase Agents in Humans

    73. Application of Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling in Cumulative Risk Assessment for N-Methyl Carbamate Insecticides

    74. Toxicological Profile of Carbaryl

    75. Aldicarb: Toxicity, Exposure and Risks to Humans

    76. Toxicology and Mode of Action of Pyrethroid Insecticides

    77. Dialkyldithiocarbamates

    78. Symmetrical and Asymmetrical Triazine Herbicides

    79. Phenylurea Herbicides

    80. Protoporphyrinogen Oxidase-Inhibiting Herbicides

    81. Chloracetanilides

    82. Paraquat

    83. Phenoxy Herbicides

    84. Dicamba

    85. Imidazolinones

    86. Toxicology of Triazolopyrimidine Herbicides

    87. A Toxicological Assessment of Sulfur as a Pesticide

    88. Cyprodinil: A Fungicide of the Anilinopyrimidine Class

    89. Captan and Folpet

    90. Mammalian Toxicokinetics and Toxicity of Chlorothalonil

    91. Inhibitors of Aromatic Acid Biosynthesis

    92. Toxicology of DDT and Some Analogs

    93. Boric Acid and Inorganic Borate Pesticides

    94. Imidacloprid: A Neonicotinoid Insecticide

    95. Interactions with the gamma-Aminobutyric Acid A-Receptor: Polychlorocycloalkanes and Recent Congeners

    96. The Role of P-glycoprotein in Preventing Developmental and Neurotoxicity: Avermectins –A Case Study

    97. DEET

    98. The Safety Assessment of Piperonyl Butoxide

    99. Rodenticides

    100. Toxicology and Safety Evaluation of the New Insect Repellent Picaridin (Saltidinâ)

    101. Ryanodine Receptor Activators

    102. Sulfuryl Fluoride

    103. Phosphine

    104. Methyl Bromide

    105. 1,3-Dichloropropene

    106. Metam-Sodium

    107. Methyl iodide


Product details

  • Language: English
  • Copyright: © Academic Press 2010
  • Published: January 6, 2010
  • Imprint: Academic Press
  • eBook ISBN: 9780080922010
  • Hardcover ISBN: 9780123743671

About the Editor in Chief

Robert Krieger

Affiliations and Expertise

University of California, Riverside, U.S.A.

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