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Hayes' Handbook of Pesticide Toxicology - 3rd Edition - ISBN: 9780123743671, 9780080922010

Hayes' Handbook of Pesticide Toxicology

3rd Edition

Principles and Agents

Editor in Chief: Robert Krieger
eBook ISBN: 9780080922010
Hardcover ISBN: 9780123743671
Imprint: Academic Press
Published Date: 6th January 2010
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The Handbook of Pesticide Toxicology is a comprehensive, two-volume reference guide to the properties, effects, and regulation of pesticides that provides the latest and most complete information to researchers investigating the environmental, agricultural, veterinary, and human-health impacts of pesticide use. Written by international experts from academia, government, and the private sector, the Handbook of Pesticide Toxicology is an in-depth examination of critical issues related to the need for, use of, and nature of chemicals used in modern pest management. This updated 3e carries on the book’s tradition of serving as the definitive reference on pesticide toxicology and recognizes the seminal contribution of Wayland J. Hayes, Jr., co-Editor of the first edition.

Key Features

  • Presents a comprehensive look at all aspects of pesticide toxicology in one reference work.
  • Clear exposition of hazard identification and dose response relationships in each chapter featuring pesticide agents and actions
  • All major classes of pesticide considered
  • Different routes of exposure critically evaluated


Libraries and institutions, hospitals, medical wholesalers. Researchers in toxicology, agriculture and public health

Table of Contents

Volume 1:

1. Dose, Time and Other Factors Influencing Toxicity

2. Pest Toxicology: The Mechanisms of Pesticide Action

3. Pest Control Agents from Natural Products

4. Public Health Pesticides

5. The Changing Role of insecticides in Structural Pest Control

6. Vertebrate Pest Control Chemicals and Their Use in Urban and Rural Environments

7. Pesticide Use and Associated Morbidity and Mortality in Veterinary Medicine

8. Pesticide Use Practices in Integrated Pest Management

9. Properties of Soil Fumigants and Their Fate in the Environment

10. Risk Assessment for Acute Exposure to Pesticides

11. Genotoxicity of Pesticides

12. Developmental and Reproductive Toxicology of Pesticides

13. Microbial Pest Control Agents: Use Patterns, Registration Requirements and Mammalian Toxicity

14. The Assessment of the Chronic Toxicity and Carcinogenicity of Pesticides

15. Immunotoxicity of Pesticides

16. Risk Assessment for Acute, Subchronic and Chronic Exposure to Pesticides: Endosulfan

17. Genetic Polymorphism and Susceptibility to Pesticides

18. Pesticides as Endocrine-Disrupting Chemicals

19. Volatile Organic Compounds from Pesticide Application and Contribution to Tropospheric Ozone

20. Environmental Transport and Fate

21. Proteomics in Pesticide Toxicology

22. Metabolomics in Pesticide Toxicology

23. Irritant Dermatitis Syndrome

24. Photoirritation

25. Allergic Contact Dermatitis

26. Contact Urticaria Syndrome

27. Percutaneous Penetration

28. Regulatory Evaluation of the Skin Effects of Pesticides

29. Neurotoxicology of Pesticides

30. A Systems Biology Approach to Assess the Impact of Pesticides on the Nervous System

31. Neurophysiological Effects of Insecticides

32. Age and Pesticide Toxicity: The Influence of Age on Pesticide Toxicity

33. Lasting Behavioral Consequences of Organophosphate Pesticide Exposure During Development

34. The Nonhuman Primate as a Translational Model for Pesticide Research

35. Pesticide Disposition

36. Introduction to Biotransformation

37. Absorption

38. Metabolism of Pesticides

39. Distribution and Pharmacokinetics

40. Metabolic Interactions of Pesticides

41. Pesticide Excretion

42. Exposure Framework

43. Sampling and Analysis for Non-Occupational Pesticide Exposure Assessments

44. Modelling and Predicting Pesticide Exposures

45. Biomonitoring: Current Tools and Approaches for Assessing Human Exposures to Pesticides

46. Pesticide Exposure from Residential and Recreational Turf

47. Lawn and Turf: Management and Environmental Issues of Turfgrass Pesticides

48. Pet Care Products Used for Insect Pest Control

49. Residential Exposure Assessment

50. Modeling Dietary Exposure with Special Sections on Modeling Aggregate and Cumulative Exposure

51. Modeling Dietary Exposure with Special Sections on Modeling Aggregate and Cumulative Exposure

52. Worker Exposure: Methods and Techniques

53. Operator and Field Worker Occupational Exposure Databases and Modeling

54. Mitigation Measures for Exposure to Pesticides

55. Regional and Global Environmental Exposure Assessments - Section Introduction

56. Ecotoxicological Risk Assessment of Pesticides the Environment

57. Environmental Transport and Fate

58. Hydrophobicity as a Key Physicochemical Parameter of Environmental Toxicology of Pesticides (Fujita et al.)

59. Pesticide Studies in Humans

60. Diagnosis and Treatment of Poisoning Due to Pesticides

61. Surveillance of Pesticide-Related Illness and Injury in Humans

62. Risk Assessment and Risk Management: The Regulatory Process

63. Perceptions of Pesticides as Risks to Human Health

Volume 2:

64. Chemistry of Organophosphorus Insecticides

65. The Metabolism of Organophosphorus Insecticides

66. Organophosphorus Insecticide Pharmacokinetics

67. Neuropathy Target Esterase

68. Cholinesterases

69. Organophosphorus-Induced Delayed Neuropathy

70. Chlorpyrifos

71. Malathion – A Review of Toxicology

72. Clinical Toxicology of Anticholinesterase Agents in Humans

73. Application of Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling in Cumulative Risk Assessment for N-Methyl Carbamate Insecticides

74. Toxicological Profile of Carbaryl

75. Aldicarb: Toxicity, Exposure and Risks to Humans

76. Toxicology and Mode of Action of Pyrethroid Insecticides

77. Dialkyldithiocarbamates

78. Symmetrical and Asymmetrical Triazine Herbicides

79. Phenylurea Herbicides

80. Protoporphyrinogen Oxidase-Inhibiting Herbicides

81. Chloracetanilides

82. Paraquat

83. Phenoxy Herbicides

84. Dicamba

85. Imidazolinones

86. Toxicology of Triazolopyrimidine Herbicides

87. A Toxicological Assessment of Sulfur as a Pesticide

88. Cyprodinil: A Fungicide of the Anilinopyrimidine Class

89. Captan and Folpet

90. Mammalian Toxicokinetics and Toxicity of Chlorothalonil

91. Inhibitors of Aromatic Acid Biosynthesis

92. Toxicology of DDT and Some Analogs

93. Boric Acid and Inorganic Borate Pesticides

94. Imidacloprid: A Neonicotinoid Insecticide

95. Interactions with the gamma-Aminobutyric Acid A-Receptor: Polychlorocycloalkanes and Recent Congeners

96. The Role of P-glycoprotein in Preventing Developmental and Neurotoxicity: Avermectins –A Case Study

97. DEET

98. The Safety Assessment of Piperonyl Butoxide

99. Rodenticides

100. Toxicology and Safety Evaluation of the New Insect Repellent Picaridin (Saltidinâ)

101. Ryanodine Receptor Activators

102. Sulfuryl Fluoride

103. Phosphine

104. Methyl Bromide

105. 1,3-Dichloropropene

106. Metam-Sodium

107. Methyl iodide


© Academic Press 2010
6th January 2010
Academic Press
eBook ISBN:
Hardcover ISBN:

About the Editor in Chief

Robert Krieger

Affiliations and Expertise

University of California, Riverside, U.S.A.

Ratings and Reviews