Handbook of Toxicologic Pathology - 1st Edition - ISBN: 9780123302205, 9781483288611

Handbook of Toxicologic Pathology

1st Edition

Editors: Wanda Haschek Colin Rousseaux
Hardcover ISBN: 9780123302205
eBook ISBN: 9781483288611
Imprint: Academic Press
Published Date: 28th August 1991
Page Count: 1127
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This is the first comprehensive reference work on toxicologic pathology, an emerging field that integrates the mechanisms of toxic injury with the resulting pathology. Chapters deal systematically with organ-specific toxic injury, describing the mechanisms of injury, morphological expression of the injury, and evaluation of the pathology. Additional chapters introduce the field to the uninitiated and address such topics as techniques used for morphological evaluation, risk assessment, and regulatory aspects. The Handbook of Toxicologic Pathology will quickly establish itself as the classic reference work in this field for years to come.

Key Features

@introbul:Key Features @bul:* Comprehensive, "user friendly" reference text on toxicologic pathology

  • Large, easy-to-use 8 1/2" x 11", double-column format
  • Systematic approach to each organ or system
  • More than 500 illustrations and 90 tables complement the text
  • Over 2,000 references for easy access to the primary literature
  • Unique chapters written by leading authorities


Toxicologic pathologists, veterinary pathologists, toxicologists, researchers in laboratory animal medicine, and public health professionals.

Table of Contents

Toxicologic Pathology: An Introduction. The Pathologist in Toxicologic Testing and Evaluation. Evaluation of Altered Morphology. Quantitative Techniques for Morphological Evaluation. Biochemical Basis of Toxicity. Biochemical Mechanisms of Toxic Cell Injury. Chemical Carcinogenesis. Limitations of Toxicologic Pathology. Regulatory Aspects and Potential Pitfalls of Toxicologic Pathology. Risk Assessment. Skin and Oral Mucosa. Gastrointestinal Tract. Pancreas. Hepatobiliary System. Urinary System. Blood and Bone Marrow. Immune System. Skeletal System. Cardiovascular and Skeletal Muscular Systems. Nervous System. Endocrine System. Respiratory System. Male Reproductive System. Female Reproductive System. The Fetus. Radiation and Heat. Chapter References. Index.


No. of pages:
© Academic Press 1991
Academic Press
eBook ISBN:

About the Editor

Wanda Haschek

Affiliations and Expertise

University of Illinois at Urbana-Champaign

Colin Rousseaux

Affiliations and Expertise

University of Ottawa