Handbook of Toxicologic Pathology

Handbook of Toxicologic Pathology

1st Edition - August 28, 1991

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  • Editors: Wanda Haschek, Colin Rousseaux
  • eBook ISBN: 9781483288611

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Description

This is the first comprehensive reference work on toxicologic pathology, an emerging field that integrates the mechanisms of toxic injury with the resulting pathology. Chapters deal systematically with organ-specific toxic injury, describing the mechanisms of injury, morphological expression of the injury, and evaluation of the pathology. Additional chapters introduce the field to the uninitiated and address such topics as techniques used for morphological evaluation, risk assessment, and regulatory aspects. The Handbook of Toxicologic Pathology will quickly establish itself as the classic reference work in this field for years to come.

Key Features

@introbul:Key Features
@bul:* Comprehensive, "user friendly" reference text on toxicologic pathology
* Large, easy-to-use 8 1/2" x 11", double-column format
* Systematic approach to each organ or system
* More than 500 illustrations and 90 tables complement the text
* Over 2,000 references for easy access to the primary literature
* Unique chapters written by leading authorities

Readership

Toxicologic pathologists, veterinary pathologists, toxicologists, researchers in laboratory animal medicine, and public health professionals.

Table of Contents

  • Toxicologic Pathology: An Introduction. The Pathologist in Toxicologic Testing and Evaluation. Evaluation of Altered Morphology. Quantitative Techniques for Morphological Evaluation. Biochemical Basis of Toxicity. Biochemical Mechanisms of Toxic Cell Injury. Chemical Carcinogenesis. Limitations of Toxicologic Pathology. Regulatory Aspects and Potential Pitfalls of Toxicologic Pathology. Risk Assessment. Skin and Oral Mucosa. Gastrointestinal Tract. Pancreas. Hepatobiliary System. Urinary System. Blood and Bone Marrow. Immune System. Skeletal System. Cardiovascular and Skeletal Muscular Systems. Nervous System. Endocrine System. Respiratory System. Male Reproductive System. Female Reproductive System. The Fetus. Radiation and Heat. Chapter References. Index.

Product details

  • No. of pages: 1127
  • Language: English
  • Copyright: © Academic Press 1991
  • Published: August 28, 1991
  • Imprint: Academic Press
  • eBook ISBN: 9781483288611

About the Editors

Wanda Haschek

Professor Haschek-Hock has served as president of the Society of Toxicologic Pathology and the Society of Toxicology’s Comparative and Veterinary Specialty Section, as well as Councilor of the American College of Veterinary Pathologists, board member of the American Board of Toxicology; as Associate Editor for Toxicological Sciences and for Toxicologic Pathology; as Editorial Board member for Fundamental and Applied Toxicology, Veterinary Pathology and Toxicologic Pathology. She has served as a member on the USFDA Veterinary Medicine Advisory Committee for the Center for Veterinary Medicine, the EPA’s FIFRA Science Advisory Panel, and National Academy of Sciences Committee. She currently serves on the Board of Directors of the C.L. Davis Foundation for the Advancement of Veterinary and Comparative Pathology. She was awarded the Society of Toxicologic Pathology’s Achievement Award in 2007 and the Midwest Regional Chapter – Society of Toxicology’s Kenneth DuBois Award in 2011. -Diplomate of the American College of Veterinary Pathologists (ACVP) -Diplomate of the American Board of Toxicology (ABT) -Fellow of the International Academy of Toxicologic Pathologists (FIATP)

Affiliations and Expertise

University of Illinois at Urbana-Champaign

Colin Rousseaux

Professor Rousseaux, BVSc [Hons], PhD, DABT, FRCPath, FIATP, FATS is a Fellow of the Royal College of Pathology, Diplomate of the American Board of Toxicology, Fellow of the Academy of Toxicological Sciences, and Fellow of the International Academy of Toxicologic Pathology. He is Professor (Adjunct) in the Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of Ottawa, Canada. He has 35 years of experience in comparative and toxicologic pathology with a research focus on herbal remedies, fetal development and teratology, and environmental pollutants. He has described, investigated, and evaluated numerous toxicologic pathology issues associated with pharmaceutical, pesticides, and agrochemicals. He has served on the editorial board of Toxicologic Pathology. He is a former president of the Society of Toxicologic Pathology.

Affiliations and Expertise

Adjunct Professor, Department of Pathology and Laboratory Medicine, University of Ottawa, Principal, Colin Rousseaux and Associates, Canada

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