Description

This is the first comprehensive reference work on toxicologic pathology, an emerging field that integrates the mechanisms of toxic injury with the resulting pathology. Chapters deal systematically with organ-specific toxic injury, describing the mechanisms of injury, morphological expression of the injury, and evaluation of the pathology. Additional chapters introduce the field to the uninitiated and address such topics as techniques used for morphological evaluation, risk assessment, and regulatory aspects. The Handbook of Toxicologic Pathology will quickly establish itself as the classic reference work in this field for years to come.

Key Features

@introbul:Key Features @bul:* Comprehensive, "user friendly" reference text on toxicologic pathology * Large, easy-to-use 8 1/2" x 11", double-column format * Systematic approach to each organ or system * More than 500 illustrations and 90 tables complement the text * Over 2,000 references for easy access to the primary literature * Unique chapters written by leading authorities

Readership

Toxicologic pathologists, veterinary pathologists, toxicologists, researchers in laboratory animal medicine, and public health professionals.

Table of Contents

Toxicologic Pathology: An Introduction. The Pathologist in Toxicologic Testing and Evaluation. Evaluation of Altered Morphology. Quantitative Techniques for Morphological Evaluation. Biochemical Basis of Toxicity. Biochemical Mechanisms of Toxic Cell Injury. Chemical Carcinogenesis. Limitations of Toxicologic Pathology. Regulatory Aspects and Potential Pitfalls of Toxicologic Pathology. Risk Assessment. Skin and Oral Mucosa. Gastrointestinal Tract. Pancreas. Hepatobiliary System. Urinary System. Blood and Bone Marrow. Immune System. Skeletal System. Cardiovascular and Skeletal Muscular Systems. Nervous System. Endocrine System. Respiratory System. Male Reproductive System. Female Reproductive System. The Fetus. Radiation and Heat. Chapter References. Index.

Details

No. of pages:
1127
Language:
English
Copyright:
© 1991
Published:
Imprint:
Academic Press
eBook ISBN:
9781483288611
Print ISBN:
9780123302205

About the editors

Wanda Haschek

Affiliations and Expertise

University of Illinois at Urbana-Champaign

Colin Rousseaux

Affiliations and Expertise

University of Ottawa