Handbook of Tissue Engineering Scaffolds - 1st Edition - ISBN: 9780081025635

Handbook of Tissue Engineering Scaffolds

1st Edition

Volume 1

Editors: Masoud Mozafari Farshid Sefat Anthony Atala
Paperback ISBN: 9780081025635
Imprint: Woodhead Publishing
Published Date: 1st June 2019
Page Count: 900
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Table of Contents

Part 1: An Introduction to Tissue Engineering Scaffolds
1. The role of scaffolds in tissue engineering
2. Scaffolds mimicking the native structure of tissues
3. Computational design of tissue engineering scaffolds
4. Research progress of scaffold materials
5. Fabrication techniques of tissue engineering scaffolds
6. Moving from clinical trials to clinical practice
7. Tissue engineering scaffolds:  Future perspectives

Part 2: Musculoskeletal Tissue Engineering Scaffolds
8. Scaffolds for bone tissue engineering
9. Scaffolds for cartilage tissue engineering
10. Scaffolds for skeletal muscle tissue engineering
11. Scaffolds for tendon tissue engineering
12. Scaffolds for ligament tissue engineering
13. Scaffolds for regeneration of meniscus lesions

Part 3: Craniomaxillofacial Tissue Engineering Scaffolds
14. Scaffolds for mandibular reconstruction
15. Scaffolds suitable for maxillary sinus augmentation
16. Scaffolds for nasal reconstruction
17. Scaffolds for repair of orbital wall defects
18. Scaffolds for cleft lip and cleft palate reconstruction
19. Scaffolds for temporomandibular joint disc engineering

Part 4: Dental Tissue Engineering Scaffolds
20. Scaffolds for dentin–pulp complex regeneration
21. Scaffolds for periodontal tissue engineering
22. Scaffolds for alveolar bone tissue engineering
23. Scaffolds for gingival tissues
24. Scaffolds that promote enamel remineralization
25. Scaffolds for dental cementum
26. Scaffolds for engineering tooth-ligament interfaces

Part 5: Cardiaovascular Tissue Engineering Scaffolds
27. Whole heart scaffolds - How to build a heart
28. Scaffolds for engineering heart valve leaflets
29. Scaffolds for blood vessels tissue engineering
30. Scaffolds for tissue engineering of functional cardiac muscle
31. Bioengineered cardiac patch scaffolds

Part 6: Neural Tissue Engineering Scaffolds
32. Scaffolds for brain tissue reconstruction
33. Scaffolds to promote spinal cord regeneration
34. Scaffolds for bridging sciatic nerve gaps
35. Scaffold for Facial Nerve Reconstruction
36. Scaffolds for Regeneration of the Auditory Nerve


Handbook of Tissue Engineering, Volume One: Scaffolds provides a comprehensive and authoritative review on recent advancements in the application and use of composite scaffolds in tissue engineering. Chapters focus on specific tissue/organ (mostly on the structure and anatomy), the materials used for treatment, natural composite scaffolds, synthetic composite scaffolds, fabrication techniques, innovative materials and approaches for scaffolds preparation, host response to the scaffolds, challenges and future perspectives, and more. Bringing all the information together in one major reference, the authors systematically review and summarize recent research findings, thus providing an in-depth understanding of scaffold use in different body systems.

Key Features

  • Dedicated to the specialist topic of composite scaffolds, featuring all human body systems
  • Covers basic fundamentals and advanced clinical applications
  • Includes up-to-date information on preparation methodology and characterization techniques
  • Highlights clinical data and case studies


Graduates, students and researchers in the fields of tissue engineering, biomaterials and regenerative medicine, biomedical science and engineering, materials science and engineering, nanoscience and engineering, biomedical nanotechnology, biotechnology


No. of pages:
© Woodhead Publishing 2019
Woodhead Publishing
Paperback ISBN:

Ratings and Reviews

About the Editors

Masoud Mozafari Editor

Dr. Masoud Mozafari received his PhD degree in Biomedical Engineering-Biomaterials from Amirkabir University of Technology (Tehran Polytechnic), in 2013. He then joined Oklahoma State University and Pennsylvania State University as a senior research associate and research visiting scholar, respectively. His research interests include the role of composite scaffolds for tissue engineering applications with respect to biological interactions. He is known for the development of strategies for the treatment of damaged tissues/organs and controlling biological substances for targeted delivery into the human body. He is currently an assistant professor and director of the “Bioengineering Research Group” in Nanotechnology and Advanced Materials Department, Materials and Energy Research Center (MERC). He is also an adjunct assistant professor in the Department of Tissue Engineering & Regenerative Medicine, Faculty of Advanced Technologies in Medicine, and Cellular and Molecular Research Center in Iran University of Medical Sciences.

Affiliations and Expertise

Bioengineering Research Group, Nanotechnology and Advanced Materials Department, Materials and Energy Research Center (MERC), Tehran, Iran

Farshid Sefat Editor

Dr Farshid Sefat is Assistant Professor in Biomedical and Electronic Engineering Department at the University of Bradford (UK) and previously was head of Biomedical Engineering Department at King Faisal University (Saudi Arabia) and also a Visiting Professor at Stevens Institute of Technology (New Jersey, USA). He completed his post doctorate research assistant at University of Sheffield (UK) in the area of cornea tissue engineering. He received his Ph.D. (2011) and BEng. (2005) degrees from University of Bradford (UK) both in Biomedical Engineering mainly focus on bone cell engineering. He also obtained his MSc. (2006) in Biomedical Engineering (Cell and Tissue Engineering) from Keele University (UK). His research is based on developing biomaterials to control cellular behaviour with particular emphasis in developing engineered materials for various tissue engineering applications. He has edited multiple books / journal special issues and is an author on >100 peer-reviewed journal articles, editorials and review papers and >30 book chapters/edited books. He is on the editorial boards of numerous journals including Materials Today, Acta Biomaterialia, IEEE, Bone, Journal of Orthopaedics & Rheumatology, Materials Science and Engineering C, J of Mechanical behaviour of Biomedical Materials, Journal of Biomechanics, Journal of Controlled Release, Medical Engineering & Physics, Biomedicine & Pharmacotherapy and many more.

Affiliations and Expertise

Lecturer in Medical Engineering, University of Bradford and Visiting Professor, Stevens Institute of Technology, NJ, USA

Anthony Atala Editor

Anthony Atala is the Director of the Wake Forest Institute for Regenerative Medicine, and the W.H. Boyce Professor and Chair of the Department of Urology at Wake Forest University. Dr. Atala is a practicing surgeon and a researcher in the area of regenerative medicine. His current work focuses on growing new human cells, tissues and organs. Dr. Atala works with several journals and serves in various roles, including Editor-in-Chief of Stem Cells- Translational Medicine, Current Stem Cell Research and Therapy, and Therapeutic Advances in Urology; as Associate Editor of Tissue Engineering and Regenerative Medicine, Rejuvenation Research, and Gene Therapy and Regulation; as Executive Board Member or Section Editor of the International Journal of Artificial Organs, Organogenesis, and Current Urology Reports; and as Editorial Board member of Expert Opinion on Biological Therapy, Biomedical Materials, Journal of Tissue Science and Engineering, 3D Printing and Additive Manufacturing, Technology, the Journal of Urology, Recent Patents on Regenerative Medicine, BioMed Central-Urology, Urology, and Current Transplantation Reports. Dr. Atala is a recipient of many awards, including the US Congress funded Christopher Columbus Foundation Award, bestowed on a living American who is currently working on a discovery that will significantly affect society, the World Technology Award in Health and Medicine, presented to individuals achieving significant and lasting progress, the Samuel D. Gross Prize, awarded every 5 years to a national leading surgical researcher by the Philadelphia Academy of Surgery, the Barringer Medal from the American Association of Genitourinary Surgeons for distinguished accomplishments, the Gold Cystoscope award from the American Urological Association for advances in the field, the Ramon Guiteras Award for pioneering research in regenerative medicine and outstanding contributions as a scholar and teacher, the Innovation Award from the Society of Manufacturing Engineers for the creation of synthetic organs, and the Rocovich Gold Medal, awarded to a distinguished scientist who has made a major impact on science toward the understanding of human disease. In 2011 he was elected to the Institute of Medicine of the National Academy of Sciences.

Affiliations and Expertise

Department of Urology, Wake Forest Institute for Regenerative Medicine, Wake Forest University, Winston-Salem, NC, USA