Handbook of Tissue Engineering Scaffolds: Volume One

Handbook of Tissue Engineering Scaffolds: Volume One

1st Edition - June 15, 2019

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  • Editors: Masoud Mozafari, Farshid Sefat, Anthony Atala
  • Paperback ISBN: 9780081025635
  • eBook ISBN: 9780081025642

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Handbook of Tissue Engineering Scaffolds: Volume One, provides a comprehensive and authoritative review on recent advancements in the application and use of composite scaffolds in tissue engineering. Chapters focus on specific tissue/organ (mostly on the structure and anatomy), the materials used for treatment, natural composite scaffolds, synthetic composite scaffolds, fabrication techniques, innovative materials and approaches for scaffolds preparation, host response to the scaffolds, challenges and future perspectives, and more. Bringing all the information together in one major reference, the authors systematically review and summarize recent research findings, thus providing an in-depth understanding of scaffold use in different body systems.

Key Features

  • Dedicated to the specialist topic of composite scaffolds, featuring all human body systems
  • Covers basic fundamentals and advanced clinical applications
  • Includes up-to-date information on preparation methodology and characterization techniques
  • Highlights clinical data and case studies


Graduates, students and researchers in the fields of tissue engineering, biomaterials and regenerative medicine, biomedical science and engineering, materials science and engineering, nanoscience and engineering, biomedical nanotechnology, biotechnology

Table of Contents

  • Part 1: An introduction to tissue engineering scaffolds
    1. Introduction to tissue engineering scaffolds
    2. The role of scaffolds in tissue engineering
    3. Scaffolds mimicking the native structure of tissues
    4. Computational design of tissue engineering scaffolds
    5. Research progress of scaffold materials
    6. Fabrication techniques of tissue engineering scaffolds
    7. Scaffolds implanted: what is next?
    8. Moving from clinical trials to clinical practice
    9. Tissue engineering scaffolds: future perspectives

    Part 2: Musculoskeletal tissue engineering scaffolds
    10. Scaffold for bone tissue engineering
    11. Scaffolds for cartilage tissue engineering
    12. Scaffolds for skeletal muscle tissue engineering
    13. Scaffolds for tendon tissue engineering
    14. Scaffolds for ligament tissue engineering
    15. Scaffolds for regeneration of meniscus lesions

    Part 3: Craniomaxillofacial tissue engineering scaffolds
    16. Scaffolds for mandibular reconstruction
    17. Scaffolds suitable for maxillary sinus augmentation
    18. Scaffolds for nasal reconstruction
    19. Scaffolds for repair of orbital wall defects
    20. Scaffolds for cleft lip and cleft palate reconstruction
    21. Scaffolds for temporomandibular joint disc engineering

    Part 4: Dental tissue engineering scaffolds
    22. Scaffolds for regeneration of the pulp–dentine complex
    23. Scaffolds for periodontal tissue engineering
    24. Tissue-engineered alloplastic scaffold for reconstruction of alveolar defects
    25. Scaffolds for gingival tissues
    26. Scaffolds that promote enamel remineralization
    27. Scaffolds for dental cementum
    28. Scaffolds for engineering tooth-ligament interfaces

    Part 5: Cardiaovascular tissue engineering scaffolds
    29. Whole heart scaffolds - how to build a heart
    30. Scaffolds for engineering heart valve
    31. Scaffolds for blood vessel tissue engineering
    32. Scaffolds for tissue engineering of functional cardiac muscle
    33. Bioengineered cardiac patch scaffolds


Product details

  • No. of pages: 790
  • Language: English
  • Copyright: © Woodhead Publishing 2019
  • Published: June 15, 2019
  • Imprint: Woodhead Publishing
  • Paperback ISBN: 9780081025635
  • eBook ISBN: 9780081025642

About the Editors

Masoud Mozafari

Masoud Mozafari
Dr. Masoud Mozafari is a Fellow at Lunenfeld Tanenbaum Research Institute, Mount Sinai Health Hospital, University of Toronto. He was previously Assistant Professor and Director of the Bioengineering Lab, at the Nanotechnology and Advanced Materials Department, Materials and Energy Research Center, Cellular and Molecular Research Center, and Department of Tissue Engineering and Regenerative Medicine of the Iran University of Medical Sciences (IUMS), Tehran, Iran. Dr. Mozafari’s research interests range across biomaterials, nanotechnology, and tissue engineering, and he is known for the development of strategies for the treatment of damaged tissues and organs, and controlling biological substances for targeted delivery into the human body. Dr. Mozafari has received several awards, including the Khwarizmi Award and the Julia Polak European Doctorate Award for outstanding translational research contributions to the field of biomaterials. He has also received the WIPO Medal for Inventors from The World Intellectual Property Organization (WIPO), in recognition of his contributions to economic and technological development. Dr. Mozafari is currently working on the editorial board of several journals.

Affiliations and Expertise

Research Fellow, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Canada

Farshid Sefat

Dr Farshid Sefat is Assistant Professor (Lecturer) in Biomedical and Electronic Engineering Department at the University of Bradford (UK) and previously was head of Biomedical Engineering Department at King Faisal University (Saudi Arabia) and also a Visiting Professor at Stevens Institute of Technology (New Jersey, USA). He completed his post doctorate research assistant at University of Sheffield (UK) in the area of cornea tissue engineering. He received his Ph.D. (2011) and BEng. (2005) degrees from University of Bradford (UK) both in Biomedical Engineering mainly focus on bone cell engineering. He also obtained his MSc. (2006) in Cell and Tissue Engineering from Keele University (UK). His research is based on developing biomaterials to control cellular behaviour with particular emphasis in developing engineered materials for various tissue engineering applications. He is an author on >100 peer-reviewed journal articles, editorials and review papers and >30 book chapters/edited books. He is on the editorial boards and reviewer of >30 numerous journals including Materials Today, Acta Biomaterialia, IEEE, Bone, MDPI, Journal of Orthopaedics & Rheumatology, Materials Science and Engineering C, Journal of Biomechanics and many more.

Affiliations and Expertise

Assistant Professor, Biomedical and Electronic Engineering Department, University of Bradford, UK

Anthony Atala

Anthony Atala, MD, is the G. Link Professor and Director of the Wake Forest Institute for Regenerative Medicine, and the W. Boyce Professor and Chair of Urology. Dr. Atala is a practicing surgeon and a researcher in the area of regenerative medicine. Fifteen applications of technologies developed in Dr. Atala's laboratory have been used clinically. He is Editor of 25 books and 3 journals. Dr. Atala has published over 800 journal articles and has received over 250 national and international patents. Dr. Atala was elected to the Institute of Medicine of the National Academies of Sciences, to the National Academy of Inventors as a Charter Fellow, and to the American Institute for Medical and Biological Engineering. Dr. Atala has led or served several national professional and government committees, including the National Institutes of Health working group on Cells and Developmental Biology, the National Institutes of Health Bioengineering Consortium, and the National Cancer Institute’s Advisory Board. He is a founding member of the Tissue Engineering Society, Regenerative Medicine Foundation, Regenerative Medicine Manufacturing Innovation Consortium, Regenerative Medicine Development Organization, and Regenerative Medicine Manufacturing Society.

Affiliations and Expertise

Department of Urology, Wake Forest Institute for Regenerative Medicine, Wake Forest University, Winston-Salem, NC, USA

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