Handbook of Neuroendocrinology

Handbook of Neuroendocrinology

1st Edition - August 31, 2011

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  • Editors: George Fink, Donald Pfaff, Jon Levine
  • Hardcover ISBN: 9780123750976
  • eBook ISBN: 9780123785541

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Neuroendocrinology, the discipline concerned with how the nervous system controls hormonal secretion and how hormones control the brain, is pivotal to physiology and medicine. Neuroendocrinology has disclosed and underpins fundamental physiological, molecular biological and genetic principles such as the regulation of gene transcription and translation, the mechanisms of chemical neurotransmission and intracellular and systemic feedback control systems. Reproduction, growth, stress, aggression, metabolism, birth, feeding and drinking and blood pressure are some of the bodily functions that are triggered and/or controlled by neuroendocrine systems. In turn, neuroendocrine dysfunction due to genetic or other deficits can lead, for example, to infertility, impotence, precocious or delayed puberty, defective or excessive growth, obesity and anorexia, Cushing’s Syndrome, hypertension or thyroid disorders. These as well as neuroendocrine tumors are some of the themes covered in the 36 chapters of the Handbook. Drafted by internationally acknowledged experts in the field, the Handbook chapters feature detailed up-to-date bibliographies as well as "how do we know?" call out sections that highlight the experimental or technical foundations for major concepts, principles, or methodological advances in each area. Aimed at senior undergraduate and graduate students, post-doctoral fellows and faculty in neuroscience, medicine, endocrinology, psychiatry, psychology and cognate disciplines, the Handbook of Neuroendocrinology satisfies an unmet need that will prove useful at the laboratory bench as well as in the office.

Key Features

  • The most comprehensive up-to-date source covering basic principles, neural regulation, hormone/brain function and behavior, and neuroendocrine pathology
  • "How do we know?" callout sections highlight core concepts
  • Heavily illustrated with over 350 figures, 4-color throughout


Researchers and clinicians in the fields of neuroendocrinology and behavior; graduate students in neuroscience and related disciplines (psychiatry, neuropharmacology, medicine & veterinary medicine); medical residents

Table of Contents

  • List of “How Do We Know?” Boxes


    About the Editors

    List of Contributors

    Notes on Nomenclature

    Chapter 1. An Introduction to Neuroendocrine Systems

    Chapter 2. Neuroendocrine GPCR Signaling

    Chapter 3. Neuroendocrine Feedback Control Systems

    Chapter 4. Evolution of Reproductive Neurohormones

    Chapter 5. Neural Control of the Anterior Lobe of the Pituitary Gland (Pars Distalis)

    Chapter 6. Neural Control of the Posterior Pituitary Gland (Neurohypophysis)

    Chapter 7. Neural Control of the Intermediate Lobe of the Pituitary Gland (Pars Intermedia) and Proopiomelanocortin

    Chapter 8. The Hypothalamic–Pituitary–Adrenal Axis and Neuroendocrine Responses to Stress

    Chapter 9. Neuroendocrine Control of Reproduction

    Chapter 10. Lifetime Regulation of Growth Hormone (GH) Secretion

    Chapter 11. Neuroendocrine Regulation of Development, Growth and Metabolism – Thyroid

    Chapter 12. Circadian Rhythms in Neuroendocrine Systems

    Chapter 13. Cardiovascular Neuroendocrinology

    Chapter 14. Neuroendocrine Regulation of Food Intake

    Chapter 15. Neuropeptide Regulation of Stress-Induced Behavior

    Chapter 16. Neuroendocrine Regulation of Body Water and Electrolytes

    Chapter 17. Sexual Differentiation of Brain and Behavior

    Chapter 18. Corticosteroid Actions on Neurotransmission

    Chapter 19. Neuroendocrine Mechanism of Puberty

    Chapter 20. Sexual Behaviors

    Chapter 21. Stress and Brain Function

    Chapter 22. Neuroendocrinology of Aggression

    Chapter 23. Chronic Social Stress

    Chapter 24. Estrogen and Cognitive Aging in Women

    Chapter 25. Hormones, Mood and Affect

    Chapter 26. Hormones and the Aging Brain

    Chapter 27. Kallmann Syndrome and Other Causes of Hypothalamic Hypogonadism and Related Development Disorders

    Chapter 28. Parental Behavior and the Perinatal Programming of Infant Development

    Chapter 29. Disorders of the Hypothalamic–Pituitary–Adrenocortical System

    Chapter 30. Disorders of the Hypothalamic–Pituitary–Gonadal Axis

    Chapter 31. Disorders of the Hypothalamic–Pituitary–Thyroid Axis

    Chapter 32. Neuroendocrine Growth Disorders – Dwarfism, Gigantism

    Chapter 33. Neuroendocrine Inherited or Induced Aromatase Enzyme Deficits

    Chapter 34. Pituitary Adenomas

    Chapter 35. Neuroendocrine Tumors

    Chapter 36. Psychoneuroendocrinology

    Subject Index

    Author Index

Product details

  • No. of pages: 894
  • Language: English
  • Copyright: © Academic Press 2011
  • Published: August 31, 2011
  • Imprint: Academic Press
  • Hardcover ISBN: 9780123750976
  • eBook ISBN: 9780123785541

About the Editors

George Fink

George Fink is a Neuroendocrinologist and Neuropharmacologist who has had a major interest in stress since the start of his career. He was recently appointed Vice President and Director of Research of the Pharmos Corporation in Israel and the United States, and is the former Director of the Medical Research Council's Brain Metabolism Unit and honorary professor in the University of Edinburgh in Scotland. Dr. Fink has published over 340 neuroendocrine papers and several authoritative books, and is past president of the European Neuroendocrine Association.

Affiliations and Expertise

Director, Mental Health Research Institute, Parkville, Victoria, Australia

Donald Pfaff

Donald W. Pfaff heads the Laboratory of Neurobiology and Behavior at The Rockefeller University. He received his scientific training at Harvard College and MIT. He is a Member of the U.S. National Academy of Sciences and a Fellow of the American Academy of Arts and Sciences. Pfaff's laboratory focuses on steroid hormones and brain function, genes influencing neuronal functions, and generalized CNS arousal. He is the author or coauthor of over 10 books and more than 900 research publications.

Affiliations and Expertise

Laboratory of Neurobiology and Behavior, Rockefeller University, New York, USA

Jon Levine

Affiliations and Expertise

Professor, Department of Neurobiology and Physiology Northwestern University, Evanston IL, USA

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  • Rodrigo C. Wed Jan 24 2018

    Good reading

    Excellent scientific and bibliographic contents. A reference textbook!