Handbook of Immunoassay Technologies

Handbook of Immunoassay Technologies

Approaches, Performances, and Applications

1st Edition - January 2, 2018

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  • Editors: Sandeep Vashist, John Luong
  • eBook ISBN: 9780128117941
  • Paperback ISBN: 9780128117620

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Handbook of Immunoassay Technologies: Approaches, Performances, and Applications unravels the role of immunoassays in the biochemical sciences. During the last four decades, a wide range of immunoassays has been developed, ranging from the conventional enzyme-linked immunosorbent assays, to the smartphone-based point-of-care formats. The advances in rapid biochemical procedures, novel biosensing schemes, fully integrated lab-on-a-chip platforms, prolonged biomolecular storage strategies, device miniaturization and interfacing, and emerging smart system technologies equipped with personalized mobile healthcare tools are paving the way to next-generation immunoassays, and are all discussed in this comprehensive text. Immunoassays play a prominent role in clinical diagnostics as they are the eyes of healthcare professionals, helping them make informed clinical decisions via confirmed disease diagnosis, and thus enabling favorable health outcomes. The faster and reliable diagnosis of infections will further control their spread to uninfected persons. Similarly, immunoassays play a prominent role in veterinary diagnostics, food analysis, environmental monitoring, defense and security, and other bioanalytical settings. Therefore, they enable the detection of a plethora of analytes, which includes disease biomarkers, pathogens, drug impurities, environmental contaminants, allergens, food adulterants, drugs of abuse and various biomolecules.

Key Features

  • Provides a valuable increase of understanding of cellular and biomedical functions
  • Gives the most updated resource in the field of immunoassays, providing the comprehensive details of various types of immunoassays that need to be performed in healthcare, and in industrial, environmental and other biochemical settings
  • Discusses all multifarious aspects of immunoassays
  • Describes the immunoassay formats, along with their principle of operation, characteristics, pros and cons, and potential biochemical and bioanalytical applications
  • Provides extensive knowledge and guided insights as detailed by experienced, renowned experts and key opinion makers in the field of immunoassays


Researchers in biochemistry, molecular immunology, biomedical engineering, healthcare professionals and other multidisciplinary scientific disciplines. Laboratory researchers and academics who use immunoassay as a tool including pathologists, biochemists, clinical and veterinary chemists, students and researchers in immunology, biochemistry and medicine

Table of Contents

  • Immunoassays: An Overview
    Antibody Immobilization and Surface Functionalization Chemistries for Immunodiagnostics
    Monoclonal Antibody Generation by Phage Display: History, State-of-the-art, and Future
    Bioanalytical Requirements and Regulatory Guidelines for Immunoassays
    Enzyme-linked Immunoassays
    Surface Plasmon Resonance-based Immunoassays: Approaches, Performance and Applications
    Lateral Flow Immunoassays
    Paper-based Immunoassays
    Acoustic Wave based Immunoassays
    Interferometry based Immunoassays
    Nano- and Micro-Materials based Immunoassays
    Microcantilever-based sensors
    Quartz crystal microbalance based sensors
    Electrochemical Immunosensors: Fundamentals and Applications in Clinical Diagnostics
    Lab-on-a-Chip Immunoassays
    Smartphone-based Immunoassays
    Immunoassays: Future Prospects and Possibilities

Product details

  • No. of pages: 496
  • Language: English
  • Copyright: © Academic Press 2018
  • Published: January 2, 2018
  • Imprint: Academic Press
  • eBook ISBN: 9780128117941
  • Paperback ISBN: 9780128117620

About the Editors

Sandeep Vashist

Dr. Sandeep K. Vashist is the Senior Discovery and R&D Processes Manager at Immunodiagnostic Systems GmbH, Germany. He worked as the Bioanalytical Scientist at Bristol-Myers Squibb Ireland; Team Leader for point-of-care (POC) diabetic monitoring at National University of Singapore; Head of Immunodiagnostics at Hahn-Schickard, Germany; Senior Scientist in immunoassays and POC testing at Klinikum rechts der Isar der Technischen Universität München, Germany; Chief Scientific Officer at Vallomed Health Care GmbH, Germany; and, Founder and Director of Vallomed Smart Health Solutions. His research outputs include many successful technology transfers; several immunoassays, IVD and POC technologies; over 250 high impact factor journal publications, conference publications, patents, books, and book chapters. He has been constantly rewarded for scientific research excellence and innovation. Further, he is the invited Editor for many reputed journals; an expert/reviewer/advisor for several international funding agencies; and, a Technology consultant to several companies in the fields of immunoassays, in vitro diagnostics, POC technologies, mobile healthcare, bioanalytical sciences, and diabetic monitoring and management.

Affiliations and Expertise

Senior Discovery and R&D Processes Manager at Immunodiagnostic Systems GmbH, Germany

John Luong

Prof John H.T. Luong is the Walton Fellow and Professor associated with the School of Chemistry of University College Cork, Ireland. He was the Professor and Division Head of Biomedical Engineering of Nanyang Technological University, Singapore. He was also a distinguished Visiting Professor at University of Zhengzhou (China), a Visiting Professor at Nanocore, National University of Singapore, Bar-Ilan University (Ramat Gan-Israel), and Institut d'Electronique, de Microélectronique et de Nanotechnologie, Université de Lille. He has received several awards for his excellent contribution in research, innovation and technology transfer. He is on the Editorial Board of several Journals and the Chief Editor of Frontiers in Biotechnology and Bioengineering- Nanobiotechnology. He has 10 patents and 330 publications with over 17,000 citations with an h-index of 71. He is the expert/reviewer/advisor/consultant for many international funding agencies and enterprises.

Affiliations and Expertise

Walton Fellow and Professor, Department of Chemistry, University College Cork, Ireland

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