Handbook of Glycomics
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Handbook of Glycomics

1st Edition - September 15, 2009

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  • Editors: Richard Cummings, J. Pierce
  • Hardcover ISBN: 9780123736000
  • eBook ISBN: 9780080920054

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Description

The Handbook of Glycomics provides the first comprehensive overview of the emerging field of glycomics, defined as the study of all complex carbohydrates in an organism or cell ("the glycome"). Beginning with analytic approaches and bioinformatics, this work provides a detailed discussion of relevant databases, data integration, and analysis. It then moves on to a discussion of specific model organism and pathogen glycomes followed by therapeutic approaches to human disorders of glycosylization. Structure and function of glycomes are included along with state-of-the-art technologies and systems approaches to the analysis of glycans.

Key Features

  • Synthesizes contributions from experts in biology, chemistry, bioinformatics, biotechnology, and medicine
  • Highlights chapters devoted to chemical synthesis, cancer glycomics and immune cell glycomics
  • Includes discussions of proteomics, mass spectrometry, NMR, array technology, and transcriptomics analytic approaches

Readership

biology researchers working in genomics, proteomics, systems biology, bioinformatics and novel therapeutics; glycobiology investigators; students in related areas

Table of Contents

  • Introduction to Glycomics

    SECTION 1: Glycoconjugate Structural Analysis 1. Glycoproteomics: N-glycan Analysis 2. Glycoproteomics: O-glycan Analysis 3. Glycosaminoglycans 4. Isotopic Labeling of Glycans for Quantitative Glycomics SECTION II: Glycotranscriptomics 5. Glycotranscriptomics SECTION III: Protein-Glycan Interactions 6. Glycan Arrays 7. Chromatographic and Mass Spectrometric Techniques

    SECTION IV: Glycobioinformatics

    8. Integration of Glycomics Knowledge and Data

    9. KEGG GLYCAN for integrated analysis of pathways, genes, and glycan structures

    10. European Glycomics Portal SECTION V: Glycomes

    11. Glycomics of the Immune System

    12. Mouse and Human

    13. Drosophila

    14. Malaria

    15. Parasitic Worms

    SECTION VI: Disease Glycomes

    16. Cancer Glycomics

    17. An Introduction to Human Disorders of Glycosylation

    18. Summary

Product details

  • No. of pages: 512
  • Language: English
  • Copyright: © Academic Press 2009
  • Published: September 15, 2009
  • Imprint: Academic Press
  • Hardcover ISBN: 9780123736000
  • eBook ISBN: 9780080920054

About the Editors

Richard Cummings

Affiliations and Expertise

Emory University School of Medicine, Atlanta, GA, USA

J. Pierce

Affiliations and Expertise

University of Georgia, Athens, USA

Ratings and Reviews

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  • Adeola O. Thu Jul 25 2019

    GLYCOMICS

    ITS SO EDUCATIVE