
Handbook of Epigenetics
The New Molecular and Medical Genetics
Description
Key Features
- Timely and comprehensive collection of fully up-to-date reviews on epigenetics that are organized into one volume and written by leading figures in the field
- Covers the latest advances in many different areas of epigenetics, ranging from basic aspects, to technologies, to clinical medicine
- Written at a verbal and technical level that can be understood by scientists and college students
- Updated to include new epigenetic discoveries, newly approved therapeutics, and clinical trials
Readership
Researchers working in genetics, biology, molecular biology, pharmaceutical science, and clinical therapy; advanced undergraduate students, graduate students, university researchers, pharmaceutical company and biotechnology researchers interested in drug development and therapies
Table of Contents
1. An Overview of Epigenetics
SECTION I: Molecular Mechanisms of Epigenetics
2. Mechanisms of DNA Methylation
3. Molecular Mechanisms of Histone Modification
4. The Epigenetics of Non-coding RNASECTION II: Additional Epigenetic Processes
5. Prions in Epigenetic Inheritance
6. Chromosomal Position Effects
7. Polycomb-group Proteins and EpigeneticsSECTION III: Epigenetic Technology
8. Analyses of Gene-specific DNA Methylation
9. Methods for Assessing Genome-wide DNA Methylation
10. Determination of Histone Modifications of Specific Genes
11. Analyses of Genome-wide Histone Modifications
12. Techniques for Genome-wide Expression of Non-coding RNA
13. Computational EpigeneticsSECTION IV: Model Organisms of Epigenetics
14. Epigenetics of Lower Organisms
15. Drosophila Epigenetics
16. Models of Mouse Epigenetic Inheritance
17. Plant EpigeneticsSECTION V: Metabolism and Epigenetics
18. Metabolic Effects on DNA Methylation
19. Metabolism and Chromatin DynamicsSECTION VI: Functions of Epigenetics
20. Epigenetics, Stem Cells and Cellular Differentiation
21. Regeneration Epigenetics
22. Epigenetics of X-chromosome Inactivation
23. Genomic Imprinting
24. Epigenetics of Memory Processes
25. Transgenerational Epigenetics
26. Aging EpigeneticsSECTION VII: Evolutionary Epigenetics
27. Evolution of Epigenetic Mechanisms
28. Adaptive Evolution and EpigeneticsSECTION VIII: Epigenetic Epidemiology
29. The Effects of Diet on Epigenetic Processes
30. Environmental Agents and Epigenetic Effects
31. Impact of Infective Agents on the Epigenome
32. Population PharmacoepigenomicsSECTION IX: Epigenetics and Human Disease
33. Cancer Epigenetics
34. The Role of Epigenetics in Immune Disorders
35. Epigenetics of Brain Disorders
36. The Epigenetics of Metabolic Diseases
37. Imprinting Defects in HumansSECTION X: Epigenetic Therapy
38. DNA Demethylating Agents in Clinical Medicine
39. Clinical Applications of Histone Deacetylase Inhibitors
40. Combination Epigenetic TherapySECTION XI: The Future of Epigenetics
41. New Directions for Epigenetic Research
Product details
- No. of pages: 682
- Language: English
- Copyright: © Academic Press 2017
- Published: July 10, 2017
- Imprint: Academic Press
- Hardcover ISBN: 9780128053881
- eBook ISBN: 9780128054772
About the Editor
Trygve Tollefsbol
