Handbook of Developmental Neurotoxicology

1st Edition

Print ISBN: 9780123911827
eBook ISBN: 9780080533438
Imprint: Academic Press
Published Date: 8th July 1998
Page Count: 748
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One of the most important issues in modern toxicology, due to its special and specific impacts, the influence of chemicals on the development of the nervous system represents a key sub-discipline of neurotoxicology. This book provides a comprehensive look at the fundamental aspects of development, the chemicals and the toxic syndromes induced, and the clinical and risk assessments of such problems.

Table of Contents

Cellular and Molecular Morphogenesis:

K. Jensen, Brain Morphogenesis and Developmental Neurotoxicology.

G.B. Grunwald, Cadherin Cell Adhesion Molecules in Normal and Abnormal Neural Development.

G. Audesirk and T. Audesirk, Neurocytoskeleton and Neuritic Development.

G.J. Harry and A.D. Toews, Myelination, Dysmyelination, and Demyelination.

Developmental Biology/Toxicology:

R.M. Greene, W. Weston, P. Nugent, M. Potchinsky, and M.M. Pisano, Signal Transduction Pathways as Targets for Induced Embryotoxicity.

M.V. Chao, H. Kong, S.O. Yoon, B. Carter, and P. C.-Bonnefil, Trophic Nerve Growth Factors.

J.M. Lauder and J. Liu, Neurotoxic and Neurotrophic Effects of GABAergic Agents on Developing Neurotransmitter Systems.

P.E. Mirkes and M.A. Shield, Apoptosis.

J.F. Grippo, Receptor Mediated.

R.H. Finnell and G.D. Bennett, The Periods of Susceptibility to Induced Malformations of the Developing Mammalian Brain.

T.B. Knudsen and J.A. Wubah, Transgenic Animal Models. Synaptogenesis and Neurotransmission:

A.G. Hendrickx and P.E. Peterson, Neural Crest Cell Migration.

H.W. Broening and W. Slikker, Ontogeny of Neurotransmitters: Monoamines.

D.A. Jett, Central Cholinergic Neurobiology.

L.G. Costa, Ontogeny of Second Messenger Systems.

T.R. Guilarte, The N-Methyl-D-Aspartate Receptor: Physiology and Neurotoxicology in the Developing Brain.

Nutrient and Chemical Disposition:

R.K. Miller, Placental Transfer.

M.R. Juchau and H. Chen, Developmental Enzymology: Xenobiotic Biotransformation. <


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© Academic Press 1998
Academic Press
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