Table of Contents

Cellular and Molecular Morphogenesis: K. Jensen, Brain Morphogenesis and Developmental Neurotoxicology. G.B. Grunwald, Cadherin Cell Adhesion Molecules in Normal and Abnormal Neural Development. G. Audesirk and T. Audesirk, Neurocytoskeleton and Neuritic Development. G.J. Harry and A.D. Toews, Myelination, Dysmyelination, and Demyelination. Developmental Biology/Toxicology: R.M. Greene, W. Weston, P. Nugent, M. Potchinsky, and M.M. Pisano, Signal Transduction Pathways as Targets for Induced Embryotoxicity. M.V. Chao, H. Kong, S.O. Yoon, B. Carter, and P. C.-Bonnefil, Trophic Nerve Growth Factors. J.M. Lauder and J. Liu, Neurotoxic and Neurotrophic Effects of GABAergic Agents on Developing Neurotransmitter Systems. P.E. Mirkes and M.A. Shield, Apoptosis. J.F. Grippo, Receptor Mediated. R.H. Finnell and G.D. Bennett, The Periods of Susceptibility to Induced Malformations of the Developing Mammalian Brain. T.B. Knudsen and J.A. Wubah, Transgenic Animal Models. Synaptogenesis and Neurotransmission: A.G. Hendrickx and P.E. Peterson, Neural Crest Cell Migration. H.W. Broening and W. Slikker, Ontogeny of Neurotransmitters: Monoamines. D.A. Jett, Central Cholinergic Neurobiology. L.G. Costa, Ontogeny of Second Messenger Systems. T.R. Guilarte, The N-Methyl-D-Aspartate Receptor: Physiology and Neurotoxicology in the Developing Brain. Nutrient and Chemical Disposition: R.K. Miller, Placental Transfer. M.R. Juchau and H. Chen, Developmental Enzymology: Xenobiotic Biotransformation. <

Details

No. of pages:
748
Language:
English
Copyright:
© 1998
Published:
Imprint:
Academic Press
Print ISBN:
9780126488609
Electronic ISBN:
9780080533438

About the authors

William Slikker, Jr.

Dr. Slikker is the Director of FDA’s National Center for Toxicological Research (NCTR). He received his Ph.D. in Pharmacology and Toxicology from the University of California at Davis. Dr. Slikker holds Adjunct Professorships in the Departments of Pediatrics, and Pharmacology and Toxicology at the University of Arkansas for Medical Sciences. He has held committee chairmanships or elected offices in several scientific societies, including the Teratology Society (serving as President) and the American Society for Pharmacology and Experimental Therapeutics (Chair, Developmental Pharmacology Section and member of the Program Committee) and co-founder and past President of the MidSouth Computational Biology and Bioinformatics Society. He is currently Associate Editor for NeuroToxicology and Toxicological Sciences and is the past President of The Academy of Toxicological Sciences, the Society of Toxicology (Presidential term ended 2013), recipient of the 2014 George H. Scott Memorial Award from The Toxicology Forum and invited to present the Warkany Lecture at the 2015 annual meeting of the Teratology Society. Dr. Slikker has authored or co-authored over 300 publications in the areas of transplancental pharmacokinetics, developmental neurotoxicology, neuroprotection, systems biology, and risk assessment. He has also served on several national/international advisory panels for the International Life Sciences Institute (ILSI)/Health and Environmental Sciences Institute (HESI), Chemical Industry Institute of Toxicology (CIIT) Centers for Health Research, Environmental Protection Agency (EPA), National Institute of Environmental Health Sciences (NIEHS), National Academy of Sciences (NAS), National Institutes of Health (NIH) and World Health Organization (WHO).

Affiliations and Expertise

National Center for Toxicological Research, Jefferson, AR, USA

Louis Chang

Louis W. Chang is a Professor in the Departments of Pathology, Pharmacology, and Toxicology at the University of Arkansas for Medical Sciences. He also served as the Director of the Toxicology Program and is the current Graduate Director of the Pathology Program in Arkansas. Aside from being the author of over 200 scientific articles, Dr. Chang also served on the editorial boards for a number of publications and scientific journals in his field. He is a well recognized scientist internationally. Dr. Chang has been recently elected as a Fellow of the Academy of Toxicological Sciences and has become a board certified Diplomate of the American Board of Forensic Examiners and a Diplomate of the American Board of Forensic Medicine. He received his B.A. from the University of Massachusetts, Amherst, his M.S. in Anatomy and Histochemistry from the Tufts University School of Medicine, and his Ph.D. in Pathology from the University of Wisconsin, Madison Medical School. Dr. Chang also received education and training from Harvard Medical School and the University of California, Los Angeles School of Medicine.

Affiliations and Expertise

University of Arkansas, Little Rock, U.S.A.