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Handbook of Biomaterials Biocompatibility - 1st Edition - ISBN: 9780081029671, 9780081029688

Handbook of Biomaterials Biocompatibility

1st Edition

Editor: Masoud Mozafari
Paperback ISBN: 9780081029671
eBook ISBN: 9780081029688
Imprint: Woodhead Publishing
Published Date: 16th June 2020
Page Count: 758
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Table of Contents

Volume I: An introduction to biocompatibility
1. Biocompatibility Definition and Issues
2. Cell-Biomaterials Interactions
3. Protein Responses to Biomaterials
4. Macrophages Responses to Biomaterials
5. Dendritic Cells Responses to Biomaterials
6. Impact of Biomaterials' Physical Properties on Cellular and Molecular Responses
7. Impact of Biomaterials' Mechanics on Cellular and Molecular Responses
8. Impact of Biomaterials' Chemistry on Cellular and Molecular Responses
9. Cell-Biomaterials Interactions: The Role of Growth Factors
10. Cell-Biomaterials Interactions: The Role of Ligand Functionalization
11. Methods of Testing Cell-Biomaterials Interactions
12. In vivo Models for Biomaterials
13. Clinical impacts of biocompatibility: What surgeons ought to know
14. Standardization and Regulation of Biomaterials

Volume II: Cellular Response to Biomaterials
15. Cellular Response to Natural Polymers
16. Cellular Response to Synthetic Polymers
17. Cellular Response to Composite Polymers
18. Cellular Response to Zirconia
19. Cellular Response to Alumina
20. Cellular Response to Carbon-family materials
21. Cellular Response to Calcium phosphate cements
22. Cellular Response to Bioactive glasses and Glass-Ceramics
23. Cellular Response to Titanium Alloys
24. Cellular Response to Co-Based Alloys
25. Cellular Response to Stainless Steels
26. Cellular Response to Nano-Biomaterials

Volume III: Tissue Response to Biomaterials
27. Central Nervous System Responses to Biomaterials
28. Peripheral Nervous System Responses to Biomaterials
29. Cardiac Responses to Biomaterials
30. Vascular Responses to Biomaterials
31. Bone Responses to Biomaterials
32. Tendon and Muscle Responses to Biomaterials
33. Cartilage Responses to Biomaterials
34. Pulmonary system Responses to Biomaterials
35. Gastrointestinal Organs' Responses to Biomaterials
36. Ocular Responses to Biomaterials
37. Skin Responses to Biomaterials



Handbook of Biomaterials Biocompatibility is a systematic reference on host response to different biomaterials, taking into account their physical, mechanical and chemical properties. The book reviews recent progress in the design and study of biomaterials biocompatibility, along with current understanding on how to control immune system response. Sections provide the fundamental theories and challenges of biomaterials biocompatibility, the role of different biomaterials physicochemical surface properties on cell responses, cell responses to different physicochemical properties of polymers, ceramics, metals, carbons and nanomaterials, and biomaterials in different tissues, such as the cardiac, nervous system, cartilage and bone.

This resource will be suitable for those working in the fields of materials science, regenerative engineering, medicine, medical devices and nanotechnology.

Key Features

  • Reviews the fundamental theories and challenges of biomaterials biocompatibility, including an overview of the standards and regulations
  • Provides an overview on the cellular and molecular mechanisms involved in host responses to biomaterials
  • Systematically looks at cellular response and tissue response to a wide range of biomaterials, including polymers, metals, ceramics, alloys and nanomaterials


Materials science, regenerative engineering, medicine, medical devices, and nanotechnology, those working in academia, R&D and the clinic


No. of pages:
© Woodhead Publishing 2020
16th June 2020
Woodhead Publishing
Paperback ISBN:
eBook ISBN:

Ratings and Reviews

About the Editor

Masoud Mozafari

Dr Masoud Mozafari has recently joined Lunenfeld-Tanenbaum Research Institute - Mount Sinai Hospital - University of Toronto as a research fellow. He is known for the development of strategies for the treatment of damaged tissues/organs. He is one of the recipients of the "WIPO Medal for Inventors" from The World Intellectual Property Organization (WIPO) for his inventions that significantly contribute to the economic and technological development in the field of biomaterials. He is an Associate Editor for Frontiers in Bioengineering and Biotechnology.

Affiliations and Expertise

Research Fellow, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Canada