Handbook of Arsenic Toxicology

Handbook of Arsenic Toxicology

2nd Edition - November 1, 2022

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  • Editor: Swaran Flora
  • Hardcover ISBN: 9780323898478

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Handbook of Arsenic Toxicology, Second Edition presents the latest findings on arsenic, including its chemistry, sources and effects on the environment and human health. The book discusses both acute and chronic effects, discussing many aspects of arsenic, from physical and chemical properties, exposure, epidemiology, organ toxicity, diagnosis, prevention and treatment. Fully updated and revised, this new edition includes new topics on risk assessment, molecular mechanisms of arsenic, advances in the integrated approach to testing, assessment and development, evaluation and application of high content predictive models, and new alternative methods (NAMS) in the context of Adverse Outcome Pathways (AOPs) to assess toxicology. This comprehensive resource allows readers to effectively assess the risks related to arsenic, providing them with all they need  to know on arsenic exposure, toxicity and toxicity prevention.

Key Features

  • Brings together current findings on the effects of arsenic on the environment and human health
  • Includes state-of-the-art techniques in arsenic toxicokinetics, speciation and molecular mechanisms
  • Provides all the information needed for effective risk assessment, prevention and countermeasures


Researchers in the fields of toxicology, pharmacology, biochemistry and environmental science. Medical practitioners

Table of Contents

  • All chapters will be revised. New chapters will include topics on:
    o Advances in the Integrated Approach to Testing and Assessment and development
    o Evaluation and application of high content predictive models
    o New alternative methods (NAMS) in the context of Adverse Outcome Pathways (AOPs) to assess toxicology
    o Molecular mechanisms of arsenic
    o Risk Assessment

    Current edition TOC:

    1. Chemistry, Occurrence and Exposure: A General Overview of Arsenic Exposure
    2. Groundwater Contamination and Its Health Effects in Bangladesh
    3. Arsenic and Fluorescence Humic Substance in Groundwater of Bangladesh: A Public Health Risk
    4. Arsenic Risk Assessment
    5. Evaluation of Novel Modified Activated Alumina as Adsorbent for Arsenic Removal
    6. Health Effects of Chronic Arsenic Toxicity
    7. Fate of Arsenic Metabolites towards Toxicity on Development of Speciation Techniques
    8. Molecular Mechanism of Arsenic Toxicity
    9. Arsenic Toxicity Mechanism: Mutagenesis and Carcinogenesis
    10. Arsenic Through the Gastrointestinal Tract
    11. Cutaneous Toxicology of Arsenic
    12. Arsenic and the Liver
    13. Arsenic and Respiratory Disorders
    14. Arsenic and the Kidney
    15. Arsenic Neurotoxicity in Humans and Experiments
    16. Developmental Arsenic Exposure Impacts Fetal Programming of the Nervous System
    17. Health Effects of Prenatal and Early Life Exposure to Inorganic Arsenic
    18. Arsenic, Kidney and Urinary Bladder Disorders
    19. Arsenic and Central Nervous System
    20. Arsenic and Cardiovascular Diseases Including the Role of Stem Cells
    21. Immunotoxic Effects of Arsenic Exposure
    22. Arsenic and Reproductive Disorders
    23. Arsenic and Cancer
    24. The Association Between Chronic Arsenic Exposure and Type 2 Diabetes: A Meta-Analysis
    25. Arsenic Biosensors: Challenges and Opportunities for High Throughput Detection
    26. Medical Countermeasures
    27. Biochemical and Molecular Basis of Arsenic Toxicity Tolerance in Plants and Microbes
    28. Arsenic Contamination and Bioremediation Potential of Marine Bacteria

Product details

  • No. of pages: 800
  • Language: English
  • Copyright: © Academic Press 2022
  • Published: November 1, 2022
  • Imprint: Academic Press
  • Hardcover ISBN: 9780323898478

About the Editor

Swaran Flora

Swaran Flora
Dr. Swaran J.S. Flora MSc, PhD, FNASc, FAEB, FABP, FSSE, Associate Director & Head of Pharmacology and Regulatory Toxicology Department at Defence Research and Development Establishment, Gwalior, India, is engaged in research related to studying the mechanism and mode of action of heavy metals with particular interest in the development of a new molecule engineered for therapy of chronic arsenic poisoning.. He has delivered lectures in USA, Germany, Australia, Italy, Czech Republic, UK etc. He has published over 260 research papers in highly rated peer reviewed journals, including more than 60 Review article/ book chapters, which have been widely cited in international literature. He is Associate Editor and Member Editorial Board of more than 25 prestigious international journals including Food & Chemical Toxicology (Elsevier), Environmental Research (Elsevier), Journal of Trace Elements in Biology & Medicine (Elsevier), Ecotoxicology and Environmental Safety (Elsevier), Human & Experimental Toxicology, Oxidative Medicine & Cell Longevity, Environmental Health & Preventive Medicine (Springer, USA), Journal of Occupational Health, BMC Journal of Integrative and Alternative Medicine and Cellular and Molecular Biology etc and Guest reviewer for more than 80 international journals. He served as Executive Board Member, International Society of Dietary Supplements and Phytotherapy (ISDSP), Italy, Member, Neurobiology Task Group, Department of Science and Technology, Govt of India, Member, Scientific Advisory Board (Drug Development), CCCRAS (Department of AAYUSH, Ministry of Health and Family Welfare, Govt of India) Member, Board of Expert Panel, Bhabha Atomic Research Center, Mumbai Member, Doctoral Committee, Indira Gandhi National Open University, New Delhi, He is a Fellow of National Academy of Sciences (India) (FNASc), Association of Biotechnologists and Pharmacy (FABP), Academy of Environment Biology (FAEB) and Society of Science and Environment (FSSE) and has delivered more than 8 Oration lectures, 200 invited lecture and has been awarded by the Madhya Pradesh State Government, Indian Council of Medical Research, and Society of Toxicology (India). He has also supervised 24 students for their PhD degree.

Affiliations and Expertise

Associate Director and Head, Pharmacology, Toxicology and Regulatory Toxicology Department, Defence Research and Development Establishment, Ministry of Defence, Government of India, Gwalior, India

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