Handbook of Animal Models of Infection

Handbook of Animal Models of Infection

Experimental Models in Antimicrobial Chemotherapy

1st Edition - May 28, 1999

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  • Editor: Oto Zak
  • Hardcover ISBN: 9780127753904
  • eBook ISBN: 9780080533551

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Handbook of Animal Models of Infection is a complete revision of a three-volume text that was published in 1986. It incorporates the major advances in the field during the past decade, in particular those concerning molecular biological procedures and new models that have been developed. It focuses on both methods and techniques, which makes it an essential and comprehensive reference as well as a benchtop manual. The Handbook will help investigators save time and effort in formulating an approach to test a new potential therapeutic agent or combination of agents for in vivo efficacy and to position the therapy for specific infections where it may have therapeutic promise. The book is divided into five sections; the first covering the general methodologies, followed by sections describing experimental bacterial, mycotic, parasitic, and viral infections.

Key Features

  • Discusses ethical and safety aspects in an introductory background section
  • Covers principles of animal care and current techniques appropriate for the use of animal models of infection
  • Details a wide range of animals including rodents, rabbits, cats, and primates
  • Provides hands-on descriptions of how to set up the model
  • Discusses the major advantages and limitations of each model
  • Ensures full coverage of bacterial, fungal, viral, and parasitic infections


Researchers in the fields of infectious disease, microbiology, virology, and parasitology. In addition, all pharmaceutical companies, medical veterinary laboratories, and those working on medical aspects, particularly antimicrobial chemotherapy and drug development, both in academia and industry.

Table of Contents

  • Sections and Section Editors:
    O. Zak, Introductory Background to Animal Models of Infection.
    C. Carbon, B. Fantin, and T. O'Reilly, Bacterial Infection Models.
    C. Carbon, B. Fantin, and T. O'Reilly, Mycotic Infection Models.
    R. Kaminsky, Parasitic Infection Models.
    E.R. Kern, Viral Infection Models.
    Subject Index.

Product details

  • No. of pages: 1136
  • Language: English
  • Copyright: © Academic Press 1999
  • Published: May 28, 1999
  • Imprint: Academic Press
  • Hardcover ISBN: 9780127753904
  • eBook ISBN: 9780080533551

About the Editor

Oto Zak

Affiliations and Expertise

Novartis Pharma Research, Basel, Switzerland

About the Author

Merle Sande

Affiliations and Expertise

Utah School of Medicine, Salt Lake City, U.S.A.

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