Gradients and Tissue Patterning

Gradients and Tissue Patterning

1st Edition - March 4, 2020

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  • Editors: Stephen Small, James Briscoe
  • Hardcover ISBN: 9780128127902
  • eBook ISBN: 9780128127919

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Gradients and Tissue Patterning, Volume 137 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics. Each chapter is written by an international board of authors.

Key Features

  • Provides the authority and expertise of leading contributors from an international board of authors
  • Presents the latest release in the Current Topics in Developmental Biology series
  • Includes the latest information on gradients and tissue patterning


Clinicians in the fields of endocrinology, rheumatology, orthopedics, pediatrics and dentistry; basic scientists in anatomy, cell and developmental biology; students and postdoctoral fellows who would like to enter these fields and make further discoveries as well as improve the treatment of major bone-related disorders

Table of Contents

  • 1. Lighting up the central dogma for predictive developmental biology
    Hernan G. Garcia, Augusto Berrocal, Yang Joon Kim, Gabriella Martini and Jiaxi Zhao
    2. Optogenetic approaches to investigate spatiotemporal signaling during development
    Katherine W. Rogers and Patrick Müller
    3. A matter of time: Formation and interpretation of the Bicoid morphogen gradient
    Anqi Huang and Timothy E. Saunders
    4. Constraints and limitations on the transcriptional response downstream of the Bicoid morphogen gradient
    Huy Tran, Aleksandra M. Walczak and Nathalie Dostatni
    5. Formation, interpretation, and regulation of the Drosophila Dorsal/NF-ΚB gradient
    Allison E. Schloop, Prasad U. Bandodkar and Gregory T. Reeves
    6. The design and logic of terminal patterning in Drosophila
    Celia M. Smits and Stanislav Y. Shvartsman
    7. Dynamic positional information: Patterning mechanism versus precision in gradient-driven systems
    Johannes Jaeger and Berta Verd
    8. Intracellular morphogens: Specifying patterns at the subcellular scale
    Lars Hubatsch and Nathan W. Goehring
    9. Insights into mammalian morphogen dynamics from embryonic stem cell systems
    Elena Camacho-Aguilar and Aryeh Warmflash
    10. Control of size, fate and time by the Hh morphogen in the eyes of flies
    David G. Miguez, Diana Garcia-Morales and Fernando Casares
    11. Genetic mechanisms controlling anterior expansion of the central nervous system
    Behzad Yaghmaeian Salmani and Stefan Thor
    12. Temporal dynamics in the formation and interpretation of Nodal and BMP morphogen gradients
    Andrew D. Economou and Caroline S. Hill
    13. Signaling regulation during gastrulation: Insights from mouse embryos and in vitro systems
    Sophie M. Morgani and Anna-Katerina Hadjantonakis
    14. Just passing through: The auxin gradient of the root meristem
    Bruno Guillotin and Kenneth D. Birnbaum
    15. Small RNAs as plant morphogens
    Simon Klesen, Kristine Hill and Marja C.P. Timmermans

Product details

  • No. of pages: 498
  • Language: English
  • Copyright: © Academic Press 2020
  • Published: March 4, 2020
  • Imprint: Academic Press
  • Hardcover ISBN: 9780128127902
  • eBook ISBN: 9780128127919

About the Serial Volume Editors

Stephen Small

Stephen J. Small is at Department of Biology, New York University, NY, USA

Affiliations and Expertise

New York University, NY, USA

James Briscoe

James Briscoe is at The Francis Crick Institute, London, UK

Affiliations and Expertise

The Francis Crick Institute, London, UK

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