Key Features

  • Access the fully searchable contents online at www.expertconsult.com.
  • Stay current on recent developments such as uricosuric therapy and inhibitor therapy; gout flare prophylaxis and colchicines; ultrasound in the diagnosis of crystal deposition diseases; imaging of gout, CPPD, and hydroxyapatitie deposition diseases; and uricase therapy of gout.
  • Manage the full range of crystal arthropathies with 25 clinically-focused chapters on pseudogout, intercritical gout, hyperuricemia, gouty arthritis, and more.
  • Treat your patients effectively using the latest information on drug treatments, from the recently-approved Uloric to Kristexx and Colcryst, which are still under review.

Table of Contents

I

Foreword

II

Introduction

1

Pathology of Crystal Deposition Diseases

2

Synovial Fluid Crystal Analysis

3

Purine Metabolism in the Pathogenesis of Hyperuricemia, and Inborn Errors of Purine Metabolism Associated with Disease

4

Renal Basis of Hyperuricemia

5

Pathogenesis of Tophus Formation and Gouty Inflammation

6

Gout: Epidemiology and Risk Factors

7

Genetics of Gout

8

Diagnosis of Gout

9

Clinical Features of Gout

10

Treatment of Acute Gout

11

Diet, Alcohol, Obesity, and Hyperuricemia

12

Uricosuric Therapy of Hyperuricemia in Gout

13

Xanthine Oxidase Inhibitor Treatment of Hyperuricemia

14

Uricase Therapy of Gout

15

Prophylaxis of Attacks of Acute Gouty Arthritis

16

Overview of Gout Therapy Strategy and Targets and Management of Refractory Disease

17

Quality of Care in Gout

18

Health-Related Quality of Life and Outcome Measures in Gout

19

Asymptomatic Hyperuricemia: Cardiovascular and renal Implications

20

Pathogenesis and Molecular Genetics of Calcium Pyrophosphate Dihydrate Crystal Deposition Disease

21

Clinical Features, Diagnosis, and Treatment of CPPD Crystal Arthropathy

22

Basic Calcium Phosphate Crystal Arthropathy

23

Crystalline Disorders Associated with Renal Disease Including Oxalate Arthropathy

24

Plain Radiography and Advanced Imaging of Gout

25

Plain Radiography and Advanced Imaging of CPPD and Hydroxyapatite

Details

No. of pages:
384
Language:
English
Copyright:
© 2012
Published:
Imprint:
Saunders
Print ISBN:
9781437728644
Electronic ISBN:
9781455703548

About the author

Robert Terkeltaub

Affiliations and Expertise

VA Rheumatology Section Chief, San Diego Professor of Medicine, University of California San Diego